[C] (LldP) COG1620 L-lactate permease 4 genomes BUD2055 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG6383 - HVO_2251 - - Hut1021 hla0624 - -

Pairwise sequence scores
Consensus score	4239	VNG6383	hla0624	HVO_2251	Hut1021
3621	VNG6383	4033	3721	2638	2722
3819	hla0624	3721	4251	2799	2872
3183	HVO_2251	2638	2799	4227	3066
3248	Hut1021	2722	2872	3066	4208

571 symbols
consensus       MTSVVILALAASIPIAVAFVLLAGLRWSAARSMGVGWLLAAAIGLTYWGMEPTWLAAAAV
#oth            12212311122231131111111111111112.1...11.2111121.1..1112211.1
VNG6383         --------------------------------:::::::::G::::::S::::::V:S::
hla0624         ::N:IS:::VGV:::G:::::::::::::::A::::::::GG::::::S:::N::L:S::
HVO_2251        ::::::::::::V::V:::::::::::::::::::::V::T:LAFAV::::::AW:G:::
Hut1021         :A:::L::::::L::::::::::::::::::::T:::VI:::L::GV::::G::F::::L

consensus       YGALQAVDIILIVFGAILLMNYLEGSGAIATIRWYFRRIEEDRRIQLLLIGLGFETIIEG
#oth            1.1.1111.1..............11.1.2....1.112.2...1.1.......1.....
VNG6383         ::::::::::::::::::::::::::::::::::::GQ::::::::V:::::::M:::::
hla0624         ::::::::::::::::::::::::::::::::::::GQ::::::::V:::::::M:::::
HVO_2251        ::::EGLN:V::::::::::::::V::S:E::::::::L:R:::::::::::::::::::
Hut1021         K:V:E:::::::::::::::::::VG:::S::::F:::V:N:::V:::::::::::::::

consensus       AAGFGTPGALAAPLFIGLGFPPLAAAVFGLFFNAPNPQFGAAGTPIIGGTGAVIEPALSG
#oth            1.............................1......1.......111.12211212.11
VNG6383         ::::::::::::::::::::::::::::::Y::::::P:::::::V::::::::D:::::
hla0624         :::::::::::::::::::::::::::::::::::::P:::::::V::::::::::::::
HVO_2251        V::::::::::::::::::::::::::::::::::::::::::::::::VSQ-::SI:PA
Hut1021         V:::::::::::::::::::::::::::::::::::::::::::::NA:VET-LSST:::

consensus       SMGVGEFLSMVSAWTGVMTGLTFVFWGLLGVFLLTYWFGD-DGERSVRGAARSTAPIAPF
#oth            222121.2121...1..2..2.11........1.2....12.21.1212.1.121.11..
VNG6383         :VS:S::::::::::::V::V:Y:::::::::F::::::NG:::::IGT:V:::L:::::
hla0624         ::::::::::I:::S::I::I:Y:::::::::F:::::::A::G::LGN:V:::L:::::
HVO_2251        A:AG:P:RQL:::::::::::::A::::::::::V:::::::D:::::::::TA::::::
Hut1021         TI::A::K:I::::::::::::::::::::::::I:::::::E::T:::::::S::MV::

consensus       ALLLGVITGGTQLAIAWFIGPALPDIAAGFVVLAVGLVLANNDILIPERRWDFPDRSTWS
#oth            ..1..22..21.111..11.11........1.112.211.3211.1.233.1..2122.2
VNG6383         ::::::V::::::V::::V::::::::::::::GI::L::K::::::DDQ::::EE::::
hla0624         :::::A:::::::V:::S:::::::::::::::::::::::::::::::E::::AE:::T
HVO_2251        ::V::GL::AV:::V:::::::::::::::A:::::V:M:DRGV:V:SE::T::::RG:L
Hut1021         ::V::::::LV:W:V:::::YS::::::::::IGL:I:M:QY:V:V::KT:T::::GR::

consensus       DTWLGGLDLDEVSRDQPKKEMPVLLAWTPYLLVALALLVTRWPDLAVAGV-VL-WIQSFS
#oth            .1.....111121211.2.1.1.11..1..11..12.......2.32212211211.211
VNG6383         :::::::::::::::::::::S:::::::::::::::::::::::T::::A::D::::::
hla0624         :::::::::::::::::::::S:::::::::::::::::::::::::::TD::G::::::
HVO_2251        :E::::::PSSLDTEE:R:R:::WM::A::VA:::V:::::::T:DLVS::--:-L:G:T
Hut1021         :::::::S::SI:D:E:T:::::W::::::::::GF:::::::G:GIE:Q:--:-L:AVT

consensus       VGIDSILGTE-LGWTLQYLYLPGTMPFIPIAILTGLLHRMDTEEMGEAWRRSIRQVAPAA
#oth            1222211.1.1111212..........2.1.11..11111.232122..11.22.1.1..
VNG6383         ::L::::::::::Y:::::::::::::::::::::F::K:::TQ:::::::::Q:I::::
hla0624         :S:::::::::::Y::::::::::::::::::::::::K:::S:::T::::::E::::::
HVO_2251        ::PYW:F:Y:TME:S:A::::::::::L:V:V::::FY:::AG::AD::VE:G::::T::
Hut1021         FE:GNL::::::::DIE::::::::::M::::G::::Y:L:V:GTV::::E:V:::::::

consensus       LTLIIAVSLTQVMIQSQTNPADLLGMMEALSRALAMGAGGALPMVSPWIGAIGSFMTGSN
#oth            1..111..1..1.11.21.12222...21..21..21..11..212..1..1.1.1....
VNG6383         ::::::::M::I:::::::T::::::::::::::::::::L::LI:::::::::::::::
hla0624         ::::::::M::::::::::T:G::::::::::::::::::L:::::::V:::::::::::
HVO_2251        V::VV:::::::::::SI::T:TI:::NV::LV::E:::A:::V:A:::::L:T:V::::
Hut1021         :::VVV:::::::QE:A:::ENIA:::QV::EV::SA::::::::V:::::L:T:V::::

consensus       TSSNILFNVLQYNAAETVGLSRAIVVAIQNVGGGLGNMISVLNIAAICGVVGIAGREGDI
#oth            .2.1...12......12.12..322.11......1...1..1.1...1..1..1.....1
VNG6383         :::::::S:::::::::::V::V:A:SL::::::::::V::::V:::::::::T:::::L
hla0624         :::::::S::::::::::E:::T:::SL::::::::::V::::V:::::::::T:::::L
HVO_2251        :T:D::::A::::::AD::I:::L::::::::::V::::::::::::S::I:::::::::
Hut1021         :V:D::::S:::::::N:::::GMI:::::::::V::::::Q::::::::::::::::::

consensus       LRKAIVPMALFALFAGVFGMLLTYVLAPGLF
#oth            ...121.112..1.1.21.2..1..11..1.
VNG6383         :::::I::::::V:::L:::::::::V::::
hla0624         ::::::::::::::::::::::::::V::::
HVO_2251        :::VV::TVV::::V::V:S::V::V:::V:
Hut1021         :::VA::TVI::::V:TV:T::V::V:::V: