4 genomes BUD2067 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_1068 Hbo0567 - Hut1253 hla0055 - -

Pairwise sequence scores
Consensus score	1165	hla0055	Hut1253	Hbo0567	HVO_1068
675	hla0055	1079	548	518	554
783	Hut1253	548	1330	552	687
881	Hbo0567	518	552	1255	751
970	HVO_1068	554	687	751	1134

185 symbols
consensus       MSGR----------A-----DGRTTVISRTVARIVVPIILVTAIALLLQGHNLPGGGFIG
#oth            12132222222222111111222111121.22.11..11.111.2.111...1......1
hla0055         ----::::::::::-:::::-------MQ:T::VT:::V::VS:S:F:::::::::::::
Hut1253         :::ESTPTTTDAET:VPQVT::D::::A:::V::::::::LV::::::::::Q::::::A
Hbo0567         ::::DIDSRPHDYE:::::::R::::::::IT:::::F::::::G:::::::::::::::
HVO_1068        :N:S::::::::::-:::::S::::::::::::::::::::::::::FR:::::::::::

consensus       AVLTTAAFALIYIIFGLDYVQSEVLARRIDP---------DGSE-QHRIVEAYRWLFGAG
#oth            1..121111.1.1111.2121221.3332311111111112112231131231123233.
hla0055         G:::::::V:::VAYD:::LE:G::G:EVE::::::::::GT:VFE::T:T:::RTLL::
Hut1253         G::::TGI::V:::Y::H::EDNL:SGT:L:RSFPLDVGDT:::SSAS:TKEFGEV:TI:
Hbo0567         ::::V:::V:::V::::::::::::RL:S:N:::::::::::--:-:SP::L::::::G:
HVO_1068        :::AA:::::V::::::EFI:R::::--:K::::::::::::::::::L::T:::MASL:

consensus       LAIAVGSGLAPMAFGAPFLTQGVVFLEHLPIYGEVELASALVFDLGVYFAVVGGLLTIVA
#oth            .2212111212222.31....11212112.1.2.2.2...22..1..121...2....11
hla0055         :VVVL:::F:G:LI:D::::::Y:HV:GI:::H:::::::::::::::LV:::S:::::S
Hut1253         :I::A:G:V:A::L:Y:::::A::::::::::::::I:::::::::::VV::::::::L:
Hbo0567         ::L::L:::V:IF::FD::::::W:FK:V:L:E:F:::::VF::F::::::::A::::::
HVO_1068        :::::::S:::L:::::::::::L::::::L:::L:V:::FA:::::F::::::::::::

consensus       EVGNE
#oth            1.12.
hla0055         V:SG:
Hut1253         V::::
Hbo0567         :::T:
HVO_1068        :::::