4 genomes BUD2078 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_1002 - Hmu2527 Hut0908 hla1643 - -

Pairwise sequence scores
Consensus score	1667	Hut0908	Hmu2527	HVO_1002	hla1643
717	Hut0908	1741	329	438	460
629	Hmu2527	329	1410	397	415
1161	HVO_1002	438	397	1814	927
1202	hla1643	460	415	927	1883

267 symbols
consensus       ------F----MAPLDV-GEPASIAEAIAAIIAFLPRIVGALLILLVGWFIGRRVARAIA
#oth            122222122222322312333323323233321211211111111211222.23213323
Hut0908         MVATGS:DQFVT:::F:DSFV::WES::KSF::E::G:::::V:::::V:L:::IGSIAH
Hmu2527         ::::::-::::------:----------------VDW::AIV:PIVAYATV:PK:GDR::
HVO_1002        ::::::-:::::Y::Q::TLTE::::LTN:VL::V::L:::::::I::::::SIA::L:T
hla1643         :MDIMG:TDPL:LQI::P:::RYLQ:S::D:::::::LI::VV::::::I:::L::G:VR

consensus       RVADRVELDEAVLATPLGAALGGEDRAIAGALGRLAKYFVYAIALLAAADALAVALLSEW
#oth            2212.221.221231.2133.1121312121213232121212.213122313232222.
Hut0908         ELVG:AG:::WFADS:IAPL::-::GSF:::V:LVV::Y:VLF:::V:IRFVGF:I:EQ:
Hmu2527         A::A::D::::::E:::::V:R-::E:::D::AG:TT:LLTL:::VISLSLVNAGQIAS:
HVO_1002        :::::::V:K::::::V:KI:::TEK:VS::F:T:G:W::::::V:::::V:::D:F:::
hla1643         :IV::T:V:RL:MN::::G::::SE:::SRS:::A:G:::::L:I:T:::::D:E:::::

consensus       VQTAASYLPSFLAGVLIIVAGFVVADFVGRAAARTEAVTETSYTPVFAAGARAFLYFVVV
#oth            222212.1122211211123.1.2.212212223222222221122113131321..122
Hut0908         :::LVV:::RA:::AA::MF:V:F:EYA::Q::GS:::QQSE:G:WVT::VK:IV::::A
Hmu2527         A:IG:R::A:L:GS:::LL::::::GY:S::LKDNDVLAGR:V::LV:LV::GVV:::S:
HVO_1002        :S:::::A:::V::L:V::L:::::::I:D:IT::R:A:::P::S:::V:T:M::::TA:
hla1643         IAA:V::::A:I:::::::I:::L::::ADI::H::T:::::::D:::D:L:V::::::T

consensus       VIGLDTMGINVAILNTIAQAVAW----GIAAAIALAVGIAVGLGARDYVAANIGDWL-G-
#oth            111.222.3123.12131112.21111.12111.111.211111221.123222213112
Hut0908         :::::ML:M:LE:VYLVVDG::SAIGL::T::::::::V:::FA:KE:AEGGL::NS:-:
Hmu2527         TLA::AI:Y:TV::::M:::::V:::::LGLG:::::::S::::SQ::::DH:AE:T:-:
HVO_1002        ::::S::::D::::F:::::F:::::::::::L:IG::G::AF::::::S::VER:M::S
hla1643         ::::G:::VD:Q::::F:::A:::::::L::G::::I:::F:::G:::::T::::::P:R

consensus       A-----TP----------P-G-EEADD
#oth            122222112211111112121233231
Hut0908         -:::::--::::::::::-:-:GS:EE
Hmu2527         -:::::--::::::::::-:-:---S:
HVO_1002        :RSVAA::VSPMGGDTDS:E:ASP:::
hla1643         :PDPES::MG:::::::Q:D:G::ST: