4 genomes BUD2091 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC1312 HVO_2330 Hbo1893 - - - NP4420A -

Pairwise sequence scores
Consensus score	2562	rrnAC1312	HVO_2330	NP4420A	Hbo1893
1837	rrnAC1312	2581	1495	1215	1369
1812	HVO_2330	1495	2653	1159	1381
1639	NP4420A	1215	1159	2640	1371
1863	Hbo1893	1369	1381	1371	2640

381 symbols
consensus       --------MGLSAAFRDQRAVSFSWGEFTGAIGDSVTVLPVVVAVAALTDLSLPHLLVGF
#oth            1111111123311322233322122212...1...1....2...213..31..212.21.
rrnAC1312       ::::::::--M:FT::::TT::L::N:L:::::::A::::::::::V::K::::VM::W:
HVO_2330        ::::::::::V:FPYG:EL::D:E:H:::::V::::::::I:::::R::::::AVV::W:
NP4420A         MYRLLALFVPPE::::TG:GF::DA::V::::::::::::L:::LGL::PA::::::A::
Hbo1893         :::::::::S:::GVFGSESPK::V:A:::::::::::::::::I::::E:::S:::L::

consensus       GVFQVVWGLYYGVPLSVEPMKALAALVIAGTLSTGELVVAGLLAGGILLVAGRTRSLRRV
#oth            1....1..11.12.2.......1.1.11.1121211112..121111.122.2.21.321
rrnAC1312       ::::::::::::::I:::::::F::::::::I:::::::::::LA:::::L:T:Q::EV:
HVO_2330        :::::::::::AA::::::::::::::L:E:VTA::ALL::FGL:VV::AI::::::G::
NP4420A         :::::I::::::::::::::::::G:A::::::H:G::A:::V:::V:::::::G::SWI
Hbo1893         A:::::::VR::L:V:::::::::::::::S:T:D::::::::::V::FT::S::T::::

consensus       SQYVGEPVVRGVQLAVALLLLETGIRLGAGDPALATLAVGVAAVVALAGRSNASALAVLA
#oth            2211121......11..11.121123.211123212211121112213222221.11.11
rrnAC1312       N:::DDT:::::::G:::V::::::G::LN::R:V:V:::IV::L::L:H:GQ::F::FV
HVO_2330        :R:I:A:::::::FG:::V::S::LE:::::LP::G:::A::::AL:TR:::V:::::::
NP4420A         Q:F::::::::::F:::C::VVAAVD:V::SVGI:AAGA:L:L::::VS:-::V::V:::
Hbo1893         :H:::::::::::::::::::::::::SL:S::F:::::::::I:SV::YRR::::V:::

consensus       VGAAVAAAATGHPTPAVPAV-AAFLASGGTLSLAAGEAALAQLAMTVGNAALATSLLLAD
#oth            1.22213332.312111.312332232332..3323.132..1.1......1...1..1.
rrnAC1312       L:::I:L:E::V::::::::D:M:MLPTM::::QT:::V:::I:V::::::::::V::::
HVO_2330        ::G:::FSDV::LSL:::P:RD:G:F:F:N::F:VV:::V:::::::::::::::V::::
NP4420A         :::VW::T:G:I:A::A:SL:EL:P:G:P:::VG:I:GL::::::::::::V::::::S:
Hbo1893         ::FG:VIPQ::L:::H::N::TFV:P:LSA::SS:L:GTA:::::::::::V::::::S:

consensus       YFDADVSADELATSMGAMNLLAVPLGAFPMCHGSGGVAGKYAFGARTAGANLVLGAGYAL
#oth            11.111.1.2.12...2...2...1.11........1...1......221.221.32.12
rrnAC1312       :::R:::::Q:SN:::L:::V:::F::::::::::::::::::::::P::::L:::::V:
HVO_2330        :::R::::::::::::::::::::::G::::::::::::::::::::::::VI::V::VV
NP4420A         LY::EI:P:R::D:::::::A::::::V::::::::L:::H::::::GT::::A:GF::G
Hbo1893         :Y:::::P::::::::V::::::::::V::::::::::::::::::::WS:I:::TL:::

consensus       AALFAVGVVAAFPLALLGVILALIAAQLGRTGFT---RTDARAFVAAIGVLGVVVNLGVA
#oth            3.22.21221.1.311...2.121132.21222211131.32321111.211.22.111.
rrnAC1312       T:FL::::IS:Y:T:::::::V:::F:::W::VS:::S::DL:V::::::V::L::::L:
HVO_2330        V::::AD::::Y:V:M::::::I:GL::A::SL:SLS:A:GYPL:V::::V::A::::::
NP4420A         L::V:-:LL::::M:::::L:VVV::S:S:VA:::::K::R:L:::GV:G:A::T:VA::
Hbo1893         ::V::::I::::::SM:::V:::V:VE:::A::D:::-::::W:AVGV:L::::A:V:::

consensus       FVAGV---LVWQRRSRA----
#oth            1.3112221212112231111
rrnAC1312       L:L:::::::Q:L:A:L::::
HVO_2330        ::G::AAW:::E:P::T::::
NP4420A         :::AT::::W::L:G--::::
Hbo1893         ::V::VCYIL:N:::D:TTPV