4 genomes BUD2107 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - pNG6158 - Hbo0316 Hmu3170 - - NP1046A -

Pairwise sequence scores
Consensus score	2195	NP1046A	Hbo0316	pNG6158	Hmu3170
1191	NP1046A	1946	885	908	986
1572	Hbo0316	885	3184	1101	1136
1617	pNG6158	908	1101	2117	1388
1715	Hmu3170	986	1136	1388	2426

407 symbols
consensus       MMHGEAAGLLAGAIALGFVHGIEPGHGWPIAASYALDQGNKWLYGAAASLILGIGHLISS
#oth            12332321123.11...21..11.1....1..2..111311.21.3112121.1...1..
NP1046A         ----MD:P:V::V::::M:::VL:D:::::::V:::::PRQ:VS:TV:A:V::V::::::
Hbo0316         -:VSDLW::IG::V:::::::V::::::::::T::MEK::::::::::GT:::::::V::
pNG6158         :L::::LPV:V::::::::::::::::::V::::::::S::::::L:S::LI::::::::
Hmu3170         ::YF:G::::I::::::AI::::::::::V::::::::T:::A::F:::::::V:::V::

consensus       IAMVGAFFYAKSYFSLTQVNEPI---GG--IGGPWVSQVAGVLLILLGIREYRSGGHHHG
#oth            2.1.21112112212111111112221122111.12132..2..12..11.1321..3.1
NP1046A         V:L:A:YVSFSAFA:FAE-----:::--::--:::MKPL::G::V::::Y::V::::V:-
Hbo0316         ::::VV::A:::::N:::-----:::--::--L::I::I:::::::::LY:L:G::::::
pNG6158         L::::V::::::S:Q::::::::SIL::VS::::-::I:::I:::G::::::TH-::S:-
Hmu3170         :::::::::::E:::::::::::TVV::LQ::::-::L:::::::A::L:::L:-::T::

consensus       ----HDHG---DHDHDTDHGHGGDHDEHTEDDGH------GSHEHHGEHDEHAHS-E---
#oth            22221211222123132.111.12.23222331122111111.21122222.32221222
NP1046A         ::::-E::DGE:AH::H::::::::---------:::::::::::SDV:H::G--:-:::
Hbo0316         GDDS::::EHD:::TH:::HD::R::G:G:H:::SHHGEH:G:S::::::G:S:HG:HDG
pNG6158         ::::----:::--Q:EV:::::Q:::::::EQ--::::::S::HS::TPPT:E:::-:::
Hmu3170         TSTG:::::::-:T:G::D::::H:HTG:D:H::GD::::::::::S:A::::Q:R:RAD

consensus       -S---------V------------------------------------------------
#oth            212222222221222211111111111111111111111111111111111111111111
NP1046A         :-:::::::::-::::::::::::::::::::::::::::::::::::::::::::::::
Hbo0316         H:HHGEHDTTH:HVGKHGRDEHGVFYAHSDDDNHGEHGVHHVHSDHDSHHSHDDHGHHNL
pNG6158         :-:::::::::-::::::::::::::::::::::::::::::::::::::::::::::::
Hmu3170         R:LVDRLILPA:NLSR::::::::::::::::::::::::::::::::::::::::::::

consensus       --------------------------------------G----ADGILGRVKSALPFVGG
#oth            1111111111111111111111111111111112222212222312322322231122..
NP1046A         ::::::::::::::::::::::::::::::::::::::-::::::N:V:T:R:Y::DG::
Hbo0316         VLGHHDSEDHDDERRHSDQHGHGDHSHHDSHDHHNDQH:HDHHE::V:A:LT::::::::
pNG6158         ::::::::::::::::::::::::::::::::::::::-::::P::P:TW::IR:GKI::
Hmu3170         :::::::::::::::::::::::::::::::::ISPPW:GEYLNEVTA:SM:TVV:::::

consensus       HSHAHG---EPDADRGLLGIAWFAFVLGFAHEEEFEIIALCAGSNYCLELMTAYALTVIV
#oth            12.3122222211111.221111.11.......1111121.1.132.....21.111.1.
NP1046A         :A:LD-::::S::E:::RTLGVT:L::::::::PIQVL:I:::TEF:::::LI:SVA:::
Hbo0316         :::S:RLGSD:-:ETS:WS::::::L::::::::::::L::T::::::::::I:::::::
pNG6158         :::E::TDPA::::::::::::::::::::::::::::G:::::T:::::::::::::::
Hmu3170         -G::::::::M:T:::::::::::::::::::::::::::::::DA:::::G::::::V:

consensus       GIVGLTLLLIAGYQRYEERVEQYTPYLPTFSAAVLVVMGLGFITGVF
#oth            1.121.1..1...2221111.211111.221.21.121.1..22.1.
NP1046A         A:LVP:::::::::THR::I:::::::::LT:::::IV:::::::::
Hbo0316         :::S:::::V:::Y:::D:::SVAEHF::I:::I:IS:::::LF:::
pNG6158         ::::::M:::::::E:::T::R::::::L:::I::::::::::A:::
Hmu3170         ::::::M::::::E:C::::::::::::V:::L::::::I::V::I: