4 genomes BUD2146 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - pNG7105 HVO_1281 - - - hla0024 NP1344A -

Pairwise sequence scores
Consensus score	2613	NP1344A	HVO_1281	pNG7105	hla0024
1428	NP1344A	2631	937	1079	1037
1584	HVO_1281	937	2686	1184	1202
2033	pNG7105	1079	1184	2686	1831
2077	hla0024	1037	1202	1831	2688

368 symbols
consensus       MRVGLVLYGSLDEQSGGFRYDRKLVEGLRAAGDDVEVVSLPWRDYRRGLLDNASPDRRLR
#oth            11...211.21122...11..12.111.111.11.11121.213.312.11132232121
NP1344A         :H::::VA:DI:SG::::Y:::R:R:R:S:R:H::T:::V:RGS:G:Q::AAL::-:::D
HVO_1281        V:::::V::P::DR:::Y:::SE::G:::::::::T:::::E:P::KR:R::VTAV::::
pNG7105         :::::T:::::::::::::::::::::::::::T::CIQ::::::H::::::G:RKL:Q:
hla0024         :::::A:::::A:::::::::::::::::R:::T::::E::::T:P:::::::L::FGD:

consensus       LRVDVDVMLQDELAHPSLLAANRALR--YPIVSIVHHLRASEPRRLAPLY--RAVERRYL
#oth            12211..211.1.11.1.132.13.3112.2.11..1.11212212211221.11.111.
NP1344A         ::GRF::VVE:G::Q:A:::V::V::::V:T:AV::M::S-QAAST:::AV::VA::SF:
HVO_1281        -AL::::L:::::C::::VG::AL:DDET:V::V::::NSL:RF:AWRRHAR::::T:::
pNG7105         :D::::::::::::::::VRT::::S::::::::::::::::::::::::::::::::::
hla0024         :::::::::::::::::::L:::D:P::::::::::::::::::::S:::::::::::::

consensus       RSVDAVVCNSAATRRAVAALGVDPDDTVVAPPAGDRFD---PAIDRAEIRARAANGPLRV
#oth            21211212..11.132112112212311.11.11.1.12111321122123..332..31
NP1344A         ::C::AIY:::::KQ:GTR:-AS:PH:A:I::GR::::L:::RPS:SSV:Q::GE:::S:
HVO_1281        ::A::F:F::ET:K:T:::V-T:::PS:::H::::::ASFGAPL:DD:::::::D:::::
pNG7105         GT:Q:::::::T::NV:TN:::::E::::::::::Q::::::D::::T:ER::TTE::Q:
hla0024         AT::G:::::::::D:::::::AR:S:::::::::::::::::::D:::AS::R:R::GA

consensus       VFVGNVEPRKGLDTLLEGLAAADADIRLTVVG-RAVDAAHVASVRALARERGIDDRVTFA
#oth            1111.221..11.1.1211.2122.13.....122..221221223111222111..211
NP1344A         ::L:::VE:::::::::::::L:::W::::::DTT::P:YT::T:K:::RLA::::::Y:
HVO_1281        :T:C:L::::NV:G::R:::R:RD:WK::::::A::::DYAD:LS:::VA::::::::::
pNG7105         ::::::S::::::::VD:V:::AV::D:::::::H::::::T::QERV::HDLA:::Q::
hla0024         I::::I:::::::::V:AV:L:::::E::::::::::EE:::E::R:V::::L:E::R:T

consensus       GRLPDAELAATLRESHVLAVPSRYEGFGIAYLEAMGFGLPAIASRAGGAAEIVTDGETGV
#oth            ...1.111.22..21.21.1..1..1..1111.1.11.11111121..12131212.1.2
NP1344A         :::::::V::H::RG:A::::::::P::M:::::::Y:CVP::TTN::P::FIR:::::C
HVO_1281        :::S::D:::::::::LF:L::H:::::::AV:::::::::LV:S::::S:L::HR:D:F
pNG7105         :::::G:::K:::S:::::::::::::::V:::G:S:::::L:T::::::D::::D::::
hla0024         :::S:::::EA::::::::::::::::::V:::G:S:::::::::::::I:T:A::::::

consensus       LVDPDDPAAVARALAELATDRDRLAAMGRAARRRFEAHPTWEETAARVRDLLADIVQATD
#oth            ..1.2111121121221121121.122231.122113..2.2113221121.31222322
NP1344A         ::P:ES:::ITDR:::::-::ET:::IST::LSA::Q:::::V:LDDAV:F:EAQC:T:-
HVO_1281        ::::T:::ELTD:V:P:CRN:R::QSLAIS::D::L:::::D::::T::SF:L:::GGA:
pNG7105         ::::::S:::::E:ERF::::::::E::W::::NY:T::D::::VG::::::S::::P:E
hla0024         :::::::V::::::D:F:::P:::::::::::::Y:R::S:A:ST::::R::::VAD:P:

consensus       --------
#oth            22211111
NP1344A         ::::::::
HVO_1281        ::::::::
pNG7105         VPA:::::
hla0024         PVEPEVAT