4 genomes BUD2157 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_1311 Hbo0231 - - hla0923 NP4278A -

Pairwise sequence scores
Consensus score	2150	HVO_1311	Hbo0231	hla0923	NP4278A
1568	HVO_1311	2163	1558	1199	1202
1525	Hbo0231	1558	2145	1163	1145
1697	hla0923	1199	1163	2139	1646
1693	NP4278A	1202	1145	1646	2181

290 symbols
consensus       MALDDPDLSGRTAFITGTSRGIGKAIALALADAGCNIVSTGKTVDADD-----DLEGTIE
#oth            123222112.21......1.....11..2..13.211......21321111121.1.1.1
HVO_1311        ::F::V:FE:::::::::::::::::::D:::R:A:V::::::::GRE:::::::P:::V
Hbo0231         --MVENK:D::V:::::::::::::L::E:::::VKV:::::::EEK::::::E:P:::V
hla0923         :::A::::::S:::::::T:::::RL::::::H::::::::::T:D::::::S::::S::
NP4278A         :SV:A:::::Q:::::::T::::::::::::EQ::::::::::SE:::YGEDK:::::::

consensus       QTAREIRERGGEAIWRQLDVRDEARVEAAIEEAIDHFGEIDIVINNAGAIQLANFEDLPA
#oth            1.11.2121.2111231111..121.2111111112..1111.1...1..12.22111.1
HVO_1311        E:TE:::::::SS::C::::::D:S:QT::D:TV:A::G::F:V::::::HM:G:::T:P
Hbo0231         E:TE:::S::::S::::I:::::ES:A::::DTVEE::G::F::::::::HI:P::ET:P
hla0923         :::::V:D::S::LALE::L::::::::VV:::::::::V:::::::S::::::IA::::
NP4278A         :::::CE:K:V::LPI::N::::D:::::V:::::::::VN::::::S::::::V:::::

consensus       NRFDLLTDVNVRGTYLTTHAALDHLRESDE-AHVLTNSPPVTADRAPGKAAYAWSKYGMS
#oth            2.1...11..1..112122.121..222.11.121211..123222..211..2..2..1
HVO_1311        K:::::M:::A::A:A::::::P::::::H::::V:F:::MP:RP::::V:::L:::::T
Hbo0231         R:Y::::E:::::::V::Q:::P::::::H:::::AF:::::NPAR::M::::V:::::T
hla0923         :::::::E::::::H:VA::FA:::AGL::::WL:S:::::VT::S::::P:::::L:::
NP4278A         ::::::::::::::::VSR:FM:::KQT::D:WI:::A::::V:::::E:P:::::M:::

consensus       FITQSLADELSGDDIGCNSLWPVAAIDSRATRHFGLGTEDDWRTPQIVCDAVLEILSRDP
#oth            1221...3..221.112.21...11.111...1..1..11...1.2111.1.2.111.1.
HVO_1311        ::A::::G::DA::V:V:A:::::::E:E::::::M::PE:::::::M::::A:LF::::
Hbo0231         IVM::::::::::::AL:::::::::E:E::::::M::PE::::::V:::::T:::G:N:
hla0923         :::L:::E::AS::V:::TF:::TT::T::::Y::::::::::::K::S:::::::::::
NP4278A         :L:L:::T::::H::::::F:::T:::T::::Y::::::::::S:D::S:T:::::::::

consensus       SACTGNAFYDEELLREAGVEDFSQYNLTEG-DPAPMSAQLFDPDYEREN-
#oth            231...11...11.221..2..13.1111222.1....21...11..331
HVO_1311        TD::::::::::::S::::D:::S:AVV::SE:G:::::::::::::--:
Hbo0231         :E::::::::::I::DV:::::D:::VV:EA::G::::H::::::::P:Q
hla0923         ::::::S::::D:::::::T:::P::::DS::::::::R::::EF:::V:
NP4278A         ASY::::V::::::AA:::::::E:::::::N:::::::M:::::::SI: