[S] (-) COG2311 Predicted membrane protein 4 genomes BUD2165 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2097 - - - Hmu3129 - hla1714 NP3452A -

Pairwise sequence scores
Consensus score	3070	NP3452A	VNG2097	Hmu3129	hla1714
2023	NP3452A	3283	1577	1602	1528
2218	VNG2097	1577	3064	1740	1827
2428	Hmu3129	1602	1740	3076	2081
2321	hla1714	1528	1827	2081	3090

435 symbols
consensus       ----------------MSRAAGPTAPSDRIVSLDALRGVALLGILLINVWAFAMPEAVLL
#oth            1111111111111111213322..1.21..12..11..1.2....1..112.21.13212
NP3452A         MPSDGRDCANDGSPTEN:GES:::::E:::::::V:::::I::::V::I:L:GL:M:AGM
VNG2097         :::::::::::::::::TTKGS::::T:::IG:::::::::::::V:::R::S:::V:::
Hmu3129         ::::::::::::::::::D::T::P::::::::::I::L:V:::::::::V:::::S:::
hla1714         ::::::::::::::::VT:D::::P::E:::A::::::::::::::::::::::::TT:F

consensus       NPTAY------GDFTGANYWAWLASHVFAKQKFITLFSALFGAGILLFVESKERDGRPAV
#oth            ..13.111111..11.2..1..122.11222..1.1.12...1.121.2211122.32.2
NP3452A         :::L::::::::::S:L::L:::V::::FE:::V:::TF::::::V:::::::AA::::R
VNG2097         ::::::::::::::::M:::::::G:LLV::::::V:TL:::T:VAM::RNR::::D:::
Hmu3129         ::QT:::::::::L::::::::::A:::::S:::::::::::::::::TD::R:::EA:M
hla1714         :::V:ADTTVY:::::::::::AF:::::QN:::::::::::::::::I::::EK:QD::

consensus       RLHYRRTGWLIAAGLGHAYLLWYGDILVAYALCALLVVAFRNWEPRRLALLGVAFLAAPF
#oth            2.12..222.122..3...1..1..1....1111121.22..21213.122.12211313
NP3452A         ::YF::::::LV:::L::::::H::::::::::GM:::FV:::R::::L:::::MF:L:S
VNG2097         T::V::SL::::F::V:::V::::::::::GVT::F:::A::::T:D:L:A:T:L::V:T
Hmu3129         G:Y:::I:L:LL:::::::::::::V:::::::G::L:S:::R::VV::R:::L::L:::
hla1714         :::::::AI:::I::M::::::::::::::GVT::V::::::L:A:K::GV::V::LFLP

consensus       LLELFA--------AITQDPDVIASQWQPAAAAIQAQIAAYRGGWLAQLDHRVPSALRRQ
#oth            222.2211111111.22212322.2212123211211121..11.21.22..1112131.
NP3452A         ::Y:VGGAGYMVAD:T:::EINA:VTAGVGGD::A:E:D::::S:TE:IQ::A:TV:ML:
VNG2097         ::T:LS:::::::::LVA::G:F::S::::DG:L::::E::::::S:::A:::D:::G::
Hmu3129         AT::::::::::::::A:G:S:::Q::::P::TL:QEV:T::S:::::M:::::T:F:::
hla1714         VV:::::::::::::::LGG:A:::::A::E:::EQ:V:T::::::E::::::::SFS::

consensus       TTGFIANTFWRAGGLMLLGMALYRWGVLTNERSSAFYRRLVAVGGTVGLAVTLAGVWYIE
#oth            .2.123312.231.2.22....122.12112.1211....112.111..12221..1.21
NP3452A         :F::AVE:::ML::::SI:::::KY:IIS:R:A:R:::::LVA:::A:::LI:T::::R:
VNG2097         :::Y::::G::TA::::Y::::FHT::T::D::R::::::::::::::::::A::::::T
Hmu3129         :S::VGS:L:::::S:F::::::::::::G:::TR:::::::::-V:::L:V::::::V:
hla1714         :::Y:NGP::QV::T::::::::::::::G:::::L::::::L:-V::::I:V:::V:::

consensus       ANDW-SAGAALLWRQFNYWGSLLLAGGYLGAVMLYARRRPTGRVTRGLAAVGRTAFSNYI
#oth            .21.12.2121112..111.1211112.111.1.2112212131112.........1..1
NP3452A         :VG:ET:PVV::AH::::::A:::SLS:VA::::FC:AAAES:AAGA:::::::::::::
VNG2097         :A:::A:S:G:::G:::::::VP:::A:::::::V:K:W:::V:::::::::::::::::
Hmu3129         ::::::::::MY:::::H:::::V::::V:::T::::W::::I:::T:::::::::T::L
hla1714         :::::::::::Y::::I:V::FP:::::::I:::::::::D:P:::::::::::::T::L

consensus       LQTVLATTIFYGHGLGLFGRLSRVELLGVVVAIWAVQIALSVAWLRRFRFGPVEWLWRTL
#oth            1...2..22.....1.1..212.112..2.211.12.13...1.1.3111..2..2..1.
NP3452A         ::::::::L:::::V:W::T:::I:::::::::::I:VP::::::::Y::::I:::::::
VNG2097         ::::V::A::::::::::::V:::AA::I:A:V:VG::::::L:V:Y:QY::L:::::A:
Hmu3129         F::::::S:::::::::::::D::::::::::::::::G:::::::F::::::::C::::
hla1714         ::::I:::V::::::::::SVT:::Q::F:LVV:V:::V:::L:::S::::::::I::::

consensus       TYRERQPIRAGE---
#oth            ..1211.31332111
NP3452A         :::QW::L:V::KEK
VNG2097         :::T:P:M::TD:::
Hmu3129         ::G::::VWR--:::
hla1714         ::G::::::NP::::