4 genomes BUD2166 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC0380 rrnAC1749 - - Hmu2173 - hla1434 NP1776A -

Pairwise sequence scores
Consensus score	1657	hla1434	Hmu2173	NP1776A	rrnAC0380	rrnAC1749
1218	hla1434	1921	983	1053	1042	1049
1280	Hmu2173	983	1728	1179	1075	1057
1349	NP1776A	1053	1179	1937	1116	1151
1331	rrnAC0380	1042	1075	1116	1612	1270
1351	rrnAC1749	1049	1057	1151	1270	1627

283 symbols
consensus       --------------------MAAIPLQ------------TADWLFVASNADLLLVGTLVT
#oth            11111111111111111111132231.22222222222232..3..43.323.13.231.
hla1434         MSDPATLALAAVDSLGAAGAPS:A:G:PLIDFVSRLVGEA:::E::F::::Y:G::A:L:
Hmu2173         ::::::::::::::::::::::G:V::::::::::::::SS::::::::::F::L::I::
NP1776A         :::::::::::::::::::::EPLA::ATDWQFAWVTLQ:T::Q::WE:RAI::Q:F:::
rrnAC0380       ::::::::::::::::::::::::L:::::::::::::::::::::VD:MG:::G::A::
rrnAC1749       :::::::::::::::::::::PPL:::::::::::::::-S::A::IG:L:::::::G::

consensus       VALTAASILLGFLAGFPAGAIEVYGRGPLRRAVETVGVVLRGTPIVVIIILLYFGLP-PQ
#oth            12..32.21...23...1..1....3121112.321.111....11.132221.112312
hla1434         IG::::::::::VV::::::V::::D:::K:V:SAA:I::::::::::L:VM::VVGV::
Hmu2173         :L::IT:LS::::::::M:::::::PDS::SV:G:::::F:::::::LVVV::::::I::
NP1776A         :L::LV:V::::::::::::::::::::::S::R::::L::::::::LMV:FF::::L:D
rrnAC0380       ::::V:::::::AI:::::::::::SDRA::L::Q:::::::::LL:::MI:::::-:--
rrnAC1749       :::::T:::::::L::::::V::::::::K:::::A::::::::LL::::::F:::-:--

consensus       -G--------------P--SVSSSAFVAATLALGLRSAAYQSQIFRGALQSVDEGQLEAA
#oth            32111111111111122332232211311311.....1.....1..1111.111..2111
hla1434         IN::::::::::::::LGVASI:::MT:GI:G::::::::::::::AT:S:::D:::::G
Hmu2173         L:::::::::::::TV:ALDIQVTP:L::A:::::::G:::::V::::I::IS:::M:G:
NP1776A         P:DITFSSITLGNTTI:EF::GFE::F::M:::::::::::::V::::I::I::::VA::
rrnAC0380       :-::::::::::::::-::::::::::T::I::::::::::::::::::::::D::::::
rrnAC1749       :-::::::::::::::-::::::::::T::I:::::::::::::::::::::::::::::

consensus       RSVGMSRLEAIRHVVVPQALRRSVPGFQNEFTIVLKDTSIAFAIGLAELLTRGQNLY-QG
#oth            .11111121.1.2.11...1...1...............1111..11....2121.1222
hla1434         ::I:L::F::V:Y::::::::::I::::::::::::::::V::::::::::::YD:F:-S
Hmu2173         ::I:::K:Q:::::IF:::I:::I:::::::::::::::V::::::::::::AE:::L:P
NP1776A         ::::L:KY:::::::::::::::::::::::::::::::::::::::::::::YD:FT:P
rrnAC0380       :A:A:::F:::::::::::::::::::::::::::::::::IV::IG::::T::::::E:
rrnAC1749       :A:::G::Q:::S::::::::::::::::::::::::::::IV:::G::::I::::::::

consensus       GQSTAVLEVILAVSLIYFVLTFATNRALDRLSDYYAIPGGES-
#oth            112..11.11.21111.....12...2..213.2111.1.331
hla1434         E:T::::::::FI:A:::::::T::::::::G::::::E:::A
Hmu2173         :RG:::M::::TITA::::::V::::T::::H:R::::::NE:
NP1776A         ::::::::::::::::::::::T::::::A::::::::::D::
rrnAC0380       :::::A::IF:::::V::::::::::S:::::::::V:E:TT:
rrnAC1749       :::::A::IF:T::::::::::V:::S::YVD:HFS:::::RA