4 genomes BUD2174 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC1116 - - - Hut0538 hla1614 NP4034A -

Pairwise sequence scores
Consensus score	2032	hla1614	NP4034A	rrnAC1116	Hut0538
1407	hla1614	2280	1136	1124	1117
1514	NP4034A	1136	2048	1171	1211
1543	rrnAC1116	1124	1171	2078	1356
1577	Hut0538	1117	1211	1356	2037

307 symbols
consensus       --------MRLLVAGGARVDAGKTTFSTGLVARTGAR-----GFKPRAGNDYWFDHDDYR
#oth            11111111131....211........11..212121211111.2......2..1.1...1
hla1614         VSPDRPDALVI:::::::::::::::::::::DLA::AGDAV:V:::::::::Y::::::
NP4034A         :::::::::::::::::E::::::::T::::::::V:::::::Y::::::G::Y:Q::::
rrnAC1116       :::::::::K:::::SD::::::::::V::LE::S:Q:::::::::::::N::::::::Q
Hut0538         :::::::::N:::::AD:::::::::::::IEH:::P:::::::::::::::::::::::

consensus       RATESGRLYGKDARRLAAAS------------PDDAAPESINPVHRLWRPTPGRGTGLLG
#oth            2.2221.......1.1.1.1111111111111.3233..21..2....2.2.1222.1..
hla1614         I:SD::::::::::::::::TRSLASVGERSR:EAIT:::::::::::::::D:-::M::
NP4034A         ::V:TE:::::::K:I:::N::::::::::::::S:P::A::::::::M::::::K::::
rrnAC1116       :::NE::::::::K:::::::::::::::::::S:V:::E:::I::::H:S::AE:::::
Hut0538         Q::::::::::::::::D:::::::::::::::G:HR:::L::M::::::K::S:S:M::

consensus       REDRRFLLDRV---TTEGGDRYVVNGTAE----LPASAAERLPLADAPRVASLAAFNDLM
#oth            22213.12...11122221221.1..21111111.3223221.122122.31222..11.
hla1614         DT::T::C:::::::::::S:F::::A::AAGL::DGL:D:F:::E:T::DDV:::::V:
NP4034A         ::G::::::::::::LD:D:S:::::D::::::::PA:TRAF:VDSS:H:E::P::::::
rrnAC1116       K:NQQ:VV:::GRPS::T:VE::::::VD::::I:E:VS:::::::::::T:I:D:::::
Hut0538         :S::E:::::::::----:::::R:::V::::::::::R:N:::S::IS::::KE::AV:

consensus       AARHLPALDSLAARIAARD-RAVVESYADIARPLS---GFQPDAVAVVEPRRARIYDGDR
#oth            333121.12221231222212111...2.1.1..1111223.......1.1.1...2.2.
hla1614         ::DY:::F:R::::V::ASVPV:::::::::G::PRDGPVK:::::::D:G:::::A:::
NP4034A         EQ::A:::SA::DE:DR:G:E:I:::::::::::::::::V:::::::::::C:::::E:
rrnAC1116       RVM:VE::E:V::D:E:T:::::I:::G:V:::::::::IE:::::::::G:::::::::
Hut0538         QRT:::::::IRET::S::::::::::S::::::::::D:::::::::::::::::P:R:

consensus       YAKACAVASGSARDGQLEERVGAVTDLIEPVATVRLPALSSEERSDPAAVADAYDHAYDA
#oth            .3..131.1.1121.11..1113.1111112.2.3....2222.2.123.111.21..12
hla1614         ::::R::::::P:E:TM::HT:T::EM:::L:::D:::::GD::G::ER:TER:GP::EM
NP4034A         :D:::S:::::::E:::::H::S::E:LD:A:::T:::::::::::VGT:::::AP:::E
rrnAC1116       :S:::QI:T:GPG::::::::PN:V::::Q::A::::::D::Q:::::::::::::::::
Hut0538         :E:::R::::::T::::::::P::::::::::S:G::::GTAR:D:::S::E::::::::

consensus       LLAAAF-
#oth            .112112
hla1614         :ID:V-:
NP4034A         :::V:-:
rrnAC1116       :::C::D
Hut0538         ::::::E