4 genomes BUD2224 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_1494 Hbo0053 - Hut1339 - - HQ2710A

Pairwise sequence scores
Consensus score	2509	Hut1339	HQ2710A	HVO_1494	Hbo0053
2064	Hut1339	2511	1806	2013	1895
2212	HQ2710A	1806	2498	2004	2143
2266	HVO_1494	2013	2004	2496	2113
2305	Hbo0053	1895	2143	2113	2507

330 symbols
consensus       MPFYGGNELATVYDDALDEGFGLIASNIAEPNIMMGLMEGAARADSDLLLQLSGGACRFA
#oth            1...1.3..12...1..11....1...1....2....1...1131..1.1.1.1..21..
Hut1339         ::::::D::GN:::E:::G::::V:::V::::T::::::::DQ::::::I:M:A::::::
HQ2710A         ::::::S::::::::::T:::::::::::::::::::I:::::K:::I::::::::ST::
HVO_1494        ::::::E:::::::E::::::::::::::::::::::::::D:M:::::::M::::::::
Hbo0053         V:::R:::::K:::::::::::::::::::::V::::::::::EN:::::::::::AT::

consensus       GNEDAVAGLKAMGTYIETIAEQYDIGVFLNMDHQTDLDFIEAQMDLGIPSSIMIDASHEP
#oth            .11.112..21..2..12..11............1.12..12.2112............1
Hut1339         ::G::E:::RS:::::D:::::::::::::::::::M:::DM:VETA::::::::::::D
HQ2710A         ::::P:D::Q:::A:::A::D:::::::::::::S::G::::::::::::::::::::::
HVO_1494        :DG::::::::::N:::::::R:::::::::::::::E:::Q:IE:D:::::::::::::
Hbo0053         ::::P:S::::::::::S::::::::::::::::::M:::::::::::::::::::::::

consensus       FEENVARSREVVEMKEDADADVLIEAELGQIKGVEDEIEAEEAFYTDPEQAVEFVDRTGC
#oth            .1...11.11..1121211211.1............1.1.1...............1..1
Hut1339         ::::::::KK:::KT:Q::EEI:V::::::::::::::V:::::::::::::::::::::
HQ2710A         :::::::::::::::K:K::::::::::::::::::N:::A:::::::::::::::::::
HVO_1494        :D::::T:::::::V:A:GS::::::::::::::::::::::::::::::::::::K::A
Hbo0053         :::::E::::::Q::::KG:::::::::::::::::::::::::::::::::::::::::

consensus       DLLAISVGTQHGVAKGKDLELRPDLARDIRQALRDHGLDTPLVLHGSSGVQPDQLQEMLQ
#oth            .................1.1.1....31.121.1...............1..1..11112
Hut1339         :::::::::::::::::::D:K::::T::KE::S:::::::::::::::L:::::SDFMN
HQ2710A         :::::::::::::::::N::::::::QE:::T::::::::::::::::::::R:::::::
HVO_1494        ::::::::::::::::::::::::::N::::::::::::::::::::::::::::::::K
Hbo0053         ::::::::::::::::::::::::::::::V:::::::::::::::::::::::::::::

consensus       HGICKVNKDTRYQYEYTRTAFDLYREDPNAIVPPEGVEDARDTFFNDTDWSPNKDVFDPR
#oth            1..................11.2.111121.....11212.11...111......2....
Hut1339         R::::::::::::::::::LY:::::E::D:::::::::Q::S::::V:::::::R::::
HQ2710A         :::::::::::::::::::::::::D:GT::::::DIDAN:E::::::E::::::I::::
HVO_1494        ::::::::::::::::::::Y:R:N:E::::::::::A::::::::E:::::::::::::
Hbo0053         ::::::::::::::::::::::H:::::E:::::::::::::::::E:E:::::::::::

consensus       VAGRDIRERIADVHADLTEVSGSAGQSRFK
#oth            .2..21.1...1.1.2.11.....12.112
Hut1339         :G:::V:::::E:Y:G:A:::::::R:LY:
HQ2710A         ::::Q::D:::::::E:::::::::H:::A
HVO_1494        :::::::::::::::::::::::::::L::
Hbo0053         :V::K:::::::::::::H:::::N:::YV