4 genomes BUD2230 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_2405 - Hmu0361 Hut0848 - - HQ3624A

Pairwise sequence scores
Consensus score	1965	HVO_2405	HQ3624A	Hmu0361	Hut0848
1542	HVO_2405	1962	1329	1055	960
1423	HQ3624A	1329	1967	979	906
1382	Hmu0361	1055	979	1977	1126
1277	Hut0848	960	906	1126	2018

275 symbols
consensus       --MGPVIDARGLAHEYPDGTTALRGIDLTIEAGERVAVIGANGAGKSTLQLLLGGLVEPT
#oth            11222111.211322.1.....232111..111.11.21.1..1.....121.1..22.2
HVO_2405        :::::::E::::T:::::::::::DVTV:::::::::::::::S::::::HV::::::::
HQ3624A         ::::S::::C:VR:::::::::IKN::V::KQQ:QI:::::::S:::::::V::::::::
Hmu0361         VTAD:::E:S:::YR:E:::::VD:V:::::::::::LL:P::::::::L::::::LP:D
Hut0848         ::VNT-L:::D:SFA::::::::G:::::::::::::IL:P::::::::LS::A::RD:A

consensus       AGSVRYFGTDADADAVRDRLGVLLQDPDDYLFNTTVREDIEYGPAQLGISRATATRRVAA
#oth            3.21211121321121.1.11112.2.21....2.....1........32132.22.123
HVO_2405        ::T:E:V:ET:::E::::::::::::::::::::::::::::::::::M::QA::Q:::H
HQ3624A         V::ITF:EKTT::ET::E:::::::N::::::::::::::::::::::YN:T::E:::ES
Hmu0361         D:::::::::QPG::::::::::T:::GE::::P::::::::::::::L:A:E:D::::E
Hut0848         S:E:::::::ES::DL:::IAHCP:T:A:::::A:::::L:::::::::D:G:::G:ID:

consensus       LAAELGLEDLLDRPPFRLSGGEQRRAAIASVLAFDPDVLLLDEPFGAVDANYRERILDLL
#oth            ..2211.23..11.........11..12.11.111.211.....222..1321131.211
HVO_2405        ::::::::S:::::::::::::KQ:::V::::::E:A:::::::::::::G::::::E:V
HQ3624A         ::DT:::I::::::::::::::KQ::::::::::::::::::::::::::T:::Q::H::
Hmu0361         ::ERFD::H:::::::::::::::::::::::SV::::::::::LSN::G:NEAEL::::
Hut0848         ::::F::DG::EK:::::::::::::SL:AA::V::ELV:::::VAD:::DH::M:::A:

consensus       D--NHAGTTIVFSTPDVDLVPAIADRVVLLGRDGSIAADGSVREVLTDTNLLRAAGLRPP
#oth            222223.2222211.12.1.131.11.212111.21112.21.11..1232.133.12..
HVO_2405        T::G:E::VVL:T-:S::A::E:::::LVV:Q::::::::P::D:::::T:::DN:::::
HQ3624A         S::::T:SMLI:T-:S:::::K::NQ:I:I:Q::G:::R:::::I::NR:::STH:::::
Hmu0361         :ELSAD:V:::T::::T:::A:V:::::::::::RVV:T::T:::::::DR::E:::A::
Hut0848         :RR:E::::::V::::A::::R::::::::D:T:::VR::Q:::::::HES:S:V:VS::

consensus       ATVQLFERALGFADIPLTVEEARERLLRQTR----
#oth            31112.2221223.3.11.11.122.232231111
HVO_2405        :::::::GI:DVD:V::::S:::AH::D:::::::
HQ3624A         Q:::M::TV:PD::::::::A:::F::KRES::::
Hmu0361         TV:E::D::-::E:L:VR::::V:::R::--::::
Hut0848         RVTEA:V::-::P:P:::::::VD::TQV:DDVDE