4 genomes BUD2258 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_1097 Hbo0602 - - hla2630 - HQ1511A

Pairwise sequence scores
Consensus score	2181	HQ1511A	hla2630	HVO_1097	Hbo0602
1456	HQ1511A	2487	1235	1243	1328
1709	hla2630	1235	2359	1424	1477
1817	HVO_1097	1243	1424	2184	1645
1837	Hbo0602	1328	1477	1645	2194

355 symbols
consensus       MSVLAA-VPFEKYHGTGNDFIVVDAD-EEVPDRPAFARTHCDRETGIDG---------EE
#oth            ..22332.122.1.......21..11123111.2...22..2.12.12211111111123
HQ1511A         ::DES:L:TAV::::::::::I::DT:K:I:N:R:::KV::S:D::VCH::::::::::T
hla2630         ::TH:-::::::::::::::L:::::A:V:G::A::::::::::::V::GDFDAERNE:S
HVO_1097        ::::NT::::::F:::::::F::::::DP:::::::::::::::A::TL:::::::::S:
Hbo0602         ::::HER::VA:::::::::::::::::S::::::::SA::N::S:::::::::::::DG

consensus       SERRGADGVLFLALEQRYNPPRVVMTLVQPDGSTAAMCGNGARVAAAWAAERTGARELMI
#oth            12..........2213123.21.....1.....1.1.......11.1..111..33.3..
HQ1511A         TD::::::::::TIN:QHT:IQ:::::I:::::::::::::::::::::::Q:::T:M::
hla2630         TG::::::::::SV:E:F::T::::::::::::::T::::::::V:L::HD:::D::F::
HVO_1097        :::::::::::::::S::D::::::::::::::V::::::::::::::::::::TN:V::
Hbo0602         :::::::::::::::G::S::::::::::::::V:::::::::C::::::::::SD::::

consensus       DTPAGTRRASLNGD--AVTIEMGAPSFAPRDVPLA--RDEELIDEEIEGLTVTAVNTGVP
#oth            1.1....1.213211132.1...2.2.3.12...1111122.1112111.11..1.....
HQ1511A         E::::::H:T:S::::TI:::::T:V:T::C:::TTD::TA::::Q:GS:SI::::::::
hla2630         ::Q:::::::V:A:AT:A:::::E:T:D:AR:::::::::P::::PV:::::::::::::
HVO_1097        :::::::::::D:T::D::V:::::::::::::::::S:D::V:T:V:::::::::::::
Hbo0602         :::::::H:VVED:::R::::::::::R::::::::::E:::VE::::::::::L:::::

consensus       HAVAFV-------DDIDSVDLESVAPPVRHADVFPEGANVTLASQNDDGS------FRQR
#oth            ..111.1111111.11.212.221..11...11..2.1..11.133121211111111..
HQ1511A         :::GM:::::::::::::IS:NDI:::I::::T::A:V:::::ELTGATQ::::::::::
hla2630         ::::::DGGRSDP:G::::::DA:::::::::::::::::N:::VV::::GDGPALID::
HVO_1097        :::::::::::::::V:D:::::::::::::S::::::::::::PDGE:G::::::::::
Hbo0602         ::I::::::::::::V:A:A::::::A::::::::D:::::V::::::::::::::::::

consensus       TFERGVEGETRSCGTGAVAVVAAAKRLGLIDGDDPVTVRPPGGALEVTVPDDGAATLTGP
#oth            .1.....1..1........11.1.2.2.21111211112....2.21..1121311.1.1
HQ1511A         :Y:::::D:::::::::::IA:V:C:I:I::T:T:I:::::::::R:::AS:QST::::S
hla2630         ::::::::::::::::::::::::R:::::::ESA:S-:::::D:::::::R:H::::::
HVO_1097        ::::::::::Q:::::::::::::::::RVS:::::::T::::::S:::::E:::L:G::
Hbo0602         ::::::::::Q:::::::::::::::V::V::::::::S::::E::I::::::P::::::

consensus       AEREFEGELDVDFRER---------------------------------------
#oth            122.221112233133111111111111111111111111111111111111111
HQ1511A         V::::QT::T:ITESSPRSTAPTMPQAKSSDSGFSSEHNNTTESSPSPSQDDVTR
hla2630         VA::Y::T:PA:P:--:::::::::::::::::::::::::::::::::::::::
HVO_1097        :VY:GD::A:IV:::::::::::::::::::::::::::::::::::::::::::
Hbo0602         ::H:::T::::TV:TP:::::::::::::::::::::::::::::::::::::::