4 genomes BUD2278 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - rrnAC3245 - - - Hut1810 hla2256 - HQ2985A

Pairwise sequence scores
Consensus score	2437	HQ2985A	hla2256	rrnAC3245	Hut1810
1789	HQ2985A	2536	1573	1571	1483
1986	hla2256	1573	2454	1672	1622
1964	rrnAC3245	1571	1672	2387	1690
1963	Hut1810	1483	1622	1690	2388

332 symbols
consensus       M---S---MDVLVTGGCGYIGSALIPLLLADDRVGDVVVLDSLASGSPRNLL--GARRDD
#oth            1222122222..1..11.......1.2.22222.2211.1.111.1..22.211133311
HQ2985A         :TTN:ASAGH::::::::::::::::Q::QN:S:SH:T:F::F::S::Q::FAT:LGST:
hla2256         :SEE:GRDTS::I:::::::::::::R::::E:::::::::::S::::A::A:::SI:::
rrnAC3245       -:::-::::::::::A::::::::::::R:::::D::::F:D:S:::::A:::::TVG:G
Hut1810         -:::-:::::::::::M:::::::L:::ADAPD::RI::::::::::::H::::E::V:G

consensus       -LEFRRGDIREYGDVESAMRGVDTVIHLAAITGAASTHDRREETFAINYDGTENVLTAAG
#oth            2.2.1...111..1..2.11.1121.........1...1.12..1.1.21.....11..1
HQ2985A         K:S:I::::QQ:::::N:VH:AE:I:::::::::::::::::::::::::::::::R:::
hla2256         ::T:::::V::::A::G:V::::A::::::::::::::::KA::::V:R:::::::::::
rrnAC3245       :::::::::::::::::::::::R::::::::::S:::E::D::::::::::::::::::
Hut1810         D:::::::V:::::::::::::::::::::::::::::::::::M:V:LE:::::V:::R

consensus       KLDVDNVVFASSCNNYGRAASTDIDETTDPDPLNPYAESKLAAERLLADAADEHDFDGTA
#oth            .11.311.1.....1....12.1.1.21111.1.....2.122.31131231232221.1
HQ2985A         :FG:K:::::::::V:::::E:E:T:H::::::::::::::K::S::R::V:TYN:::::
hla2256         :F::E:::V:::::::::::::::::E:EQN:::::::::V:C::::NE:IEA:G:::::
rrnAC3245       ::G::H::::::::V::::T:::::::V::::I:::::T::QS:T::QEYCE:F:MT:::
Hut1810         ::::G:L:::::::::::::T:::::::E:::::::::A:V:::DAV::F:::T:ANA:S

consensus       LRMSTNYGHAPGVRFNLVVNHFVFRALTDRPLTVYGDGSNWRPFIHVRDAARAYAHAACN
#oth            ...1..1.311.1.......1....1..1..................1.1...1.2..22
HQ2985A         ::::::::Y::::::::::::::::::::::::::::::::::::::H::::::::::::
hla2256         ::::::::WSL::::::::::::::G:::::::::::::::::::::::::::::D::LS
rrnAC3245       :::A::F::S::I:::::::Y::::::::::::::::::::::::::::::::::E:::D
Hut1810         ::::::::F:::::::::::::::::::G::::::::::::::::::::S:::F::::R:

consensus       PDSWDEAVYNVGSNDGNYRISEIADIVREELAP-LDVTYLEDEHPGPSYHVNFDRLAETG
#oth            .12.2231....1322.11.21..21.21.1122111...1..1............3..1
HQ2985A         :QQ:SQFC::::ASTQ:FQ:ET::QA:::::DQT:EI:::R:::::::::::::::G::K
hla2256         ::A:::R:::::::::::::A:::E::::::DRD:::::::::Q::::::::::::::::
rrnAC3245       ::::::P::::::M:A::Q::::::::AD:V:::V:::::::::::::::::::::S:::
Hut1810         ::::PK:::::::EA::::::::::::S::V:::V:::::::::::::::::::::E:::

consensus       FEPEWTLREGIRDLATQLRDNARREITA----
#oth            11121..11.1211.23113332322211111
HQ2985A         YQ:KY::Q:::TE::::FTEMKS:T:::EQGL
hla2256         ::T::::::::::I:DE::GD::E:V::::::
rrnAC3245       :::S::::::V::::EKFTT:V------::::
Hut1810         ::::::::N:VG::::V:::--:Q::D:::::