4 genomes BUD2281 6 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG5192 VNG6409 pNG6117 - - - - - NP6016A HQ2137A HQ3583A

Pairwise sequence scores
Consensus score	824	VNG6409	HQ2137A	HQ3583A	VNG5192	pNG6117	NP6016A
332	VNG6409	458	294	290	298	268	253
693	HQ2137A	294	833	760	312	547	531
676	HQ3583A	290	760	830	303	518	511
374	VNG5192	298	312	303	478	320	349
663	pNG6117	268	547	518	320	834	691
654	NP6016A	253	531	511	349	691	851

109 symbols
consensus       MPDTDALYDVREQTGNPAHASVDDVVDLVI-RAR-PRENHENAHFDEAMAAVVDRYGTEA
#oth            1221223131112122131111111331124112411231221111331.221211.213
VNG6409         ------------------------------:---:-------------::DI:E:H:I:T
HQ2137A         :TE:::::E::::::::::::::::TT::LE:::D:::::H::::::::::::::::A::
HQ3583A         :TE:::::::::R:E::::::::::IA::LD:::K:::::H::::::::::::N:::A::
VNG5192         ------------------------------:---:------------M::T:::::::DP
pNG6117         ::::E:N:N::::::::E::::::::::::Y::QN::TE::D::::T:V::L:::::::S
NP6016A         ::::EPS::::::::D:D::::::::::::H::QA::TD::D::::RT::T:I:T:::DP

consensus       VRTVIHRILVDHYPFRTATVDLEMRNVDGVRIGTAASWFLRELNAQDDD
#oth            .1...3.1..111......23.111.1...1...1.222.3...11312
VNG6409         :Q:::R::::E:::::::::::::::::::W:::::TGY:::::SEQ:S
HQ2137A         :::::::V::E:::::::::T:D:::F:::::::T:V:T:::::::G::
HQ3583A         :::::::V::E:::::::::N:DI::F:::::::T:V:T:::::::G::
VNG5192         :::::Q:V:::::::::::H::::H::::::::::::Q::T:::::H::
pNG6117         :::::N:::::DE::::::NG:::::::::::::::::::E:::::::H
NP6016A         :::::::::::DE::::::NG:::::::::::::::::::K::::::S: