4 genomes BUD2304 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_2441 - - - hla0283 NP0760A HQ1309A

Pairwise sequence scores
Consensus score	2430	NP0760A	HQ1309A	HVO_2441	hla0283
1814	NP0760A	2435	1466	1492	1626
1841	HQ1309A	1466	2472	1507	1650
1908	HVO_2441	1492	1507	2613	1686
2046	hla0283	1626	1650	1686	2518

368 symbols
consensus       MGLARFLAKRAIQ-------------------GVVVIWGVVTVVFGLRFITPGDPVTFLA
#oth            122321111.3311111111111111111111.22121..1.1..3..111..2.22222
NP0760A         :S::K:::::TL:::::::::::::::::::::LF::::::::::F:::L:::::TIA:T
HQ1309A         ::YS:::L:::S:::::::::::::::::::::::::::::::::T::Y::::S::::I:
HVO_2441        V:GPLRR:H:RVRDEPAVVDVAVEVPHQTLAP:A:RHL::I:::::::::S::::ANV:L
hla0283         :A:G:::L::G:::::::::::::::::::::::L:V:::::A::L:::::::N::::V:

consensus       PLDASAELRAQIAAELGLNRPLYVQYIDYIGGL--PRGDLGQSLAAGTNASTRVFARLPA
#oth            .1.11312.1121111..13..11..311231111231.1.31323113112312111.1
NP0760A         :P:V:D:R::EL:::::::D::H:::T::LFQ:::A:::::EAM:S:R::N:VLLE::::
HQ1309A         :::::QA::EE::M:Y:::::::::::E:VV::LP:NI:M:::F::::SV:SQ:::A::R
HVO_2441        :P:VDP:V:::VI::::::E::::::WEF:S:V:::F::::L::VTR:PV:A::V:::::
hla0283         ::::::::::::::D:::DQ:::I::V::::::::LQ::M:Y:YLR::E:::I::::V::

consensus       TLELAVAATVVAVVIAIPLGVISATRRHEPADYGATLFSLVGISTPNFWLGIMLILVLAV
#oth            12...1...2..1211.....1..11.1..1..1..2..............2..11211.
NP0760A         :I:::::::::::I::::::::::R::::::::::::::::::::::::::::::IFV::
HQ1309A         S::::::::L:::ALS:::::::::N::::T::A::T::::::::::::::L::T:L:::
HVO_2441        :::::I:::::::::::::::L::::::::::::::V::::::::::::::V::::::::
hla0283         :V:::::::I::I::::::::::::::R::::::::::::::::::::::::::::::S:

consensus       QFDAFPTGRRPIGFAAA--------NGLAVLL---AVGAAISG----LGTWLWHITLPAI
#oth            12.31..1312112333211111112.232222213222312.1111321.12111...1
NP0760A         SV:FL:::G:H:T:T::W:::::::G::----:::LFEGD:::::::V:::FAQLI::::
HQ1309A         :::I::::----:M:RV::::::::::TPL::VD::LRYLL::RPQVMLR::S::::::V
HVO_2441        :L:::::SQ::::L---::::::::D:I::::AGGD:::::R:::::F::::::::::::
hla0283         :::L:::S::::::FETFTFLVTVE:::S:PM:::N:::FLD::::::R::::::::::V

consensus       TLGTYFTALITRLTRSGMLDELGQAYVRAARAKGLPETLVRYKHALRNTLIPIVTVLGLQ
#oth            1........1........111..13.12.3....1..1.2211.1.2...1.12..1...
NP0760A         A::::::::::::::::::E:::K:::K:C:::::::::TM:::V::::::::L::::::
HQ1309A         :::::::::V:::::::::::::KQ:IT:L::::T::::::FR:::K:::V:::::::::
HVO_2441        ::::::::::::::::::::Q:::T::::T::::::::::::::::::::::VI::I:::
hla0283         :::::::::V::::::::IE::::P::::::::::::S:IQ:::::Q:::::::::::::

consensus       LGTLIGGAVITEAVFAWPGLGSLLIDAINARDWPLIQGSLIVIGAGFVLINIAVDALYAY
#oth            ........1...2..1.....1.2.11.12.1.221..1111113...21.13..11...
NP0760A         ::::::::I:::E::::::::T::::::GE:::T:::::I:I::I:::V:::::::::::
HQ1309A         ::::::::::::R::::::::::::::::::Q:VIL::C:V:V:::::IV:TV:::I:::
HVO_2441        :::::::::::::::::::::::I:NS:::::::VL::::::VAV::::V::L:::::::
hla0283         :::::::::::::::S:::::T:V:::::V::::::::::::::T:::::::F::S::::

consensus       LNPRVAA-
#oth            11.2.332
NP0760A         :D:::S:E
HQ1309A         :::E:TV:
HVO_2441        V::Q::YD
hla0283         :::::VH: