3 genomes BUD2592 3 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - - Hbo3981 Hmu2678 Hut0245 - - -

Pairwise sequence scores
Consensus score	2541	Hut0245	Hbo3981	Hmu2678
1653	Hut0245	2831	1365	1228
2096	Hbo3981	1365	2544	1607
1905	Hmu2678	1228	1607	2501

385 symbols
consensus       VKHTDSDTTDGEEFTFETQ-SAVETSRRERLREFYEEFIYKPGLVALDDWRTRIGGLILL
#oth            111112112.121111112112..111111121..111..1..1.111.1.121.111.2
Hut0245         ------MS::ELQW:YDAE:D:::VTL:DKAQ:::RNR::E::I:V:::::FIA::::::
Hbo3981         :::::T::V::S::::::S::S:::::::::S::::::::::::::WS:::::::S:L:V
Hmu2678         ::::::::-:::::V::::T:T:::::S::::D::::::::::::::::S::L:::V::F

consensus       VYILIATIGAWVWPYPETNQAPRL--------------------LPPFQNLNYPLGTTAT
#oth            111.2111.211211.2111211211111111111111111111211122111...1121
Hut0245         M:V:V::::V:LV::::IHLT:E:NLAPAFNWHSLVNIGGFNLAY:T:HD:S::::::K:
Hbo3981         ::::MG:V:::::R::S::::::F::::::::::::::::::::V::L::::::::::::
Hmu2678         :F::::L::TR:Y:A:V:::VE:S:::::::::::::::::::::K::ETM:A:::SNPS

consensus       GRDLAALIIHATPDMLIMVTAGGAFATGIALIIGTVAGYKGGRIDRAITMASDIAMSIPG
#oth            .21121121.1..2.1.1.11.1211.21.222...1.....22.1211221.1..1...
Hut0245         ::SIFG:LV:S::K:M:::IS::::::IV:T:L::::::::::V:G::S:FI::::T:::
Hbo3981         :Q:::::::::::::::::::::IW::::::V::::::::::S:::LL:S:::V::::::
Hmu2678         :T::L:QV:::::S:::L::::AV:S:F::VFT:::S:::::TT::V::TI:::::::::

consensus       LPLVMVLAVAFQ-----------------PE-----NPALIGILITINYWAGLGRAIRSQ
#oth            ...1....121211111111111111111..111111.121.1111....2.........
Hut0245         ::::::::L:::DLEVLGIGIGFAQLGQL::PLNVLR::T::MI:M::::G:::::::::
Hbo3981         :::I:::::V:S::::::::::::::::::::::::::I:::::::::::::::::::::
Hmu2678         :::::::::TIK:::::::::::::::::::::::::::VV:::L:::::S:::::::::

consensus       VLTLRQESYVEASRTMGVSTRRILTKDIIPNLMPYILVNFVNAARYVIFAAVGLYFLGVL
#oth            ...1.211............21.11..1.......1.11.11...111.12....1..1.
Hut0245         :::::::N::::::::::::WK:IL::V:::::::::I:::::::F:V:S::::::::::
Hbo3981         :::I:GN:::::::::::::T::::::::::::::V::S:::::::::::S:::::::I:
Hmu2678         :::::E::::::::::::::::::::::::::::::::::AF::::C:::G::::Y::::

consensus       PADLANWGVQLNDAYNDGGALAGLSIAYWLIAPMIAIAGLSLALILLAQGLDRVFNPRVR
#oth            .2121...12122..2221.121212211112.121122.1.211..1.1...1......
Hut0245         :T:V:::::MIS:::GQ-::I:::::WN::FP:VF:MLF:A:G::::S:S::::::::::
Hbo3981         :FSTL::::T::L::TT::::YLP:L::::::::V::M:::::M::::::::::::::::
Hmu2678         ::::::::L::DS::::YS::V:SGSE:LV:V:::P::L:::S:V::::::::I::::::

consensus       TRLAG-ESESIAEDDDEDVHTGGL-
#oth            .1.111112122.2.2121211221
Hut0245         :K:SSFDAIDSD:::V:E:MNE--:
Hbo3981         ::::::::T:T::G:E::TV::V:T
Hmu2678         :::::::::::E:E::DV:::::V: