[E] (DdpA) COG0747 ABC-type dipeptide transport system, periplasmic component 3 genomes BUD2616 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2358 - - Hbo0573 Hbo2816 - - hla2627 - -

Pairwise sequence scores
Consensus score	4939	VNG2358	Hbo2816	hla2627	Hbo0573
3742	VNG2358	5124	3338	673	1381
3868	Hbo2816	3338	5109	822	1452
1246	hla2627	673	822	5051	1077
2112	Hbo0573	1381	1452	1077	4926

939 symbols
consensus       ----------RRPNGNQDNSAAIGRRRWLKALGATGVA-GLAGCSGNDSDGTATSGDSDA
#oth            111111122232221222323322..22111.122.1.221...1.13222222123133
VNG2358         MANRDNHARPS:::TD:ST:E:HS:::V::::::::::A:V:::L:GG::DS:ATAT:E-
Hbo2816         ::::::::::M:D:T::GGG:SF::::LI:Y:A:::::TS::::::G::S::::T:::T:
hla2627         :::::::MLR:HTD:TD:::RH::::Q::S:::IA::::T:::::::EG::GDG:DG::G
Hbo0573         ::::::::::-M:S::T:--KR:D::S::::::VG:A::::::::::QNQN:E:::KGGT

consensus       ETGSPAEDTTEAEDSSD-------------------------------------------
#oth            221123312223322231111111111111111111111111111111111111111111
VNG2358         ::S::DTE:LQP:N---:::::::::::::::::::::::::::::::::::::::::::
Hbo2816         TS::T:G::::QPS:DE:::::::::::::::::::::::::::::::::::::::::::
hla2627         GN::DGS:GSDGS:G::GGNSVEVGNFPQFGVDDLYGEEVARNLARQAFEQSEYDYSFDG
Hbo0573         ::SE:T:ES:::G:::G:::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
VNG2358         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo2816         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2627         GDLITPEGDQVEIDIYHSAGQETSQLTAEFIAQELGNNLGINVVVEAIDGTRFNNEYWTA
Hbo0573         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
VNG2358         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo2816         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2627         EPQGGTDTVNGEDVEWANPTPQNPGPQSVTSNEPWDMSIVFGLNTYPLNPLTNEVFFDGP
Hbo0573         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ----IPAG----------------------------------------------------
#oth            1111213.1111111111111111111111111111111111111111111111111111
VNG2358         ::::::R:::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo2816         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2627         NSFYN:V:YYPEFDATGLFEEARQATSRDELRESFVEIFENLAQEQPYITLLFSDDLVGY
Hbo0573         ::::RSI:::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ----------------------------GTFKEATSATTNGLNALRNGDGNTTARIAAVM
#oth            1111111111111111111111111111.112312112222..31232123122213321
VNG2358         ::::::::::::::::::::::::::::::::V::TS:::::::F:I:::Q:S::VNS::
Hbo2816         ::::::::::::::::::::::::::::::::K:VT:::::::VF:V:::E:::::EL::
hla2627         NPDLNGPIENFSNGWDLPAWHFNDPSVS:SYDTV:::GFTT::P:Y:TENGAGNA::RAL
Hbo0573         ::::::::::::::::::::::::::::::YR::L::DAKS::F:FHS:T:::KFVD:T:

consensus       DQGFDR-GDEYDEILPLWFEDFTVEEDVKQIEITLRDNLQFGEPYGELTADDYLWNIQNL
#oth            .21131213223212.1121231122122211121.1..22122..21..1.21132211
VNG2358         :A::S:T:EA:ED:::::::::S:S:P:D::::::::::EY:NG::::::::::::LN::
Hbo2816         ::::I:L:P:::N::::::::V:::QP:N::::K::E::::::E:::::::::::C:D:I
hla2627         :::YTF:-::NQ:YF::LYDMS:--::G:VWTFEV:E::::S::::QV::E:FVYL::E:
Hbo0573         :YAY:F:-KDIG::V:M:V:SY:-:K:K:EWTF::::::RWSD:::D:::E:WVYTA:::

consensus       W----------KADWAAFAYSADF-VG---KPITFEKVDKYTIRETIPEPRP-FFPYNEP
#oth            21111111111232.13222232121122222222.121122222.11322111222122
VNG2358         :::::::::::RP::T::T::HL:N::ADNT:::::::::::::::::::::::::::::
Hbo2816         ::::::::::::::::S:::AN::Y::KED:::Q::::::::::::::SS::::::::::
hla2627         H::::::::::QSE::NT:A::SW:--:::DGVEV:QTGEFEFQA:LE----:--TA:LL
Hbo0573         YGAKAPGESKT:EN::GVVQYS:W:--::::NL:I::AG:RKLKV:L:G:Q:A:IASTAF

consensus       LGGRY-----PIPKDLAKPYVEEEDADGLEQDEELMRAAFNGNLGPWDLKEWNRQSVMAF
#oth            122321111111.12.111...22.21..11.112221311....121122.312.2232
VNG2358         :::M::::::::::A:::::::A:::::::::::V:::::::::::::::R:SQ::::::
Hbo2816         :SYQF:::::::::E::::::::Q::E:::K:DSI:::T:::::::::::N:KQ::::E:
hla2627         WPET:DPLLY:::R::VE:::::::V:::::::::LELQ:T::::AFT:D::::G:GTQY
Hbo0573         W:::C:::::-L::::V:G:::DK:IE::K:::::NSLSYT:::::Y:YE::Q:E:RFVA

consensus       ERADDYYLRDWAKRDDRVPDVFAEAPYFDEYHLQYFNEQSTARAALKAGEIDRAA-IPST
#oth            1.111....321232212.121111.2.11222222312211131.23112132311.12
VNG2358         :::E:::::Q:::::::::E:M:N::::::F:M::::KA::::E:::G:::::VS:::::
Hbo2816         :::E:::::K:::E::::::::::::F:::::::::DK:Q:::Q::Q:D:::T:Y:::::
hla2627         T:N:E:::::INEG----::L:S:G:L:E:ASISVVE::ASRLG::ET::A:S:::::PE
Hbo0573         T::::::::EV:GSEE-I:ER:::::::EK:E:KIIG:E::RL:S::E:DLTYFEDV::Q

consensus       KVESFRQDEGLKLYKNPYRPWSGYLGINQRANGWQ-----QLRNKEVRHAMAHAYSNDFI
#oth            2222132322222212.2212222222.1.2...3111112112111.2.2121221321
VNG2358         D:PE::DQG:IE:::::::S::::::::H:::::T::::::::::K:::::::I:H:E::
Hbo2816         :IS:YK:K:::::::::::S::::::::::::::S::::::::::K:::::::I:N::::
hla2627         QF::YDE::NVTVR:I:-T:YNMIISV:::D::::SGPGNLFQIT:F:Q:V:A:V:KQQL
Hbo0573         :::Q:Q:MDH::-FRF:PN:FCSMAYY:::S:::E:::::M:QR::::R:LST:I:KKA:

consensus       VENILRGRAEVQNTLQPAWGPYYPDDEVTFDG-----SLEKARRLLKEGTSN-DYGYSGD
#oth            221112.213122.21.3.11221313222311111122221232211221312111211
VNG2358         :::::N:::G:::::H:T::::A:ENPT::S::::::::DE:::::::::::::::::::
Hbo2816         :N:::K:::::::::H::::::S:::V:::::::::::::::KQ:::::::S::::::::
hla2627         IDGVY::L:STHF:W::R:SEF::G::-----:::::---------------:-------
Hbo0573         A:::Y::FPT:AH:F::E:S:W:LT:K:EQF:VGDSYGS::::KMM::AL:DTN:::D::

consensus       KFVGPDGEQVELTIVYQSGQQDDLRAA-YLKKRLGKVGIKLAQQTTSWPNLMQNYFNCTN
#oth            221222121111231122233222221122122121211123232222222231223313
VNG2358         T::::::N::::::::::::T::::::::::::::::::::N:E::::::::S:::KT:E
Hbo2816         :::::::::::::L::::DEL::::::::::::::::::::T:::::::S::K:::::::
hla2627         ---------------------------:--------------------------------
Hbo0573         :L:DGN::::::SF::RA:S:NNQTV:EFF:QE:A:I:::V:PTNGGPF:TL::KYML:S

consensus       TADGFSD----G--------PS-YNAGP-DDAVSAQPWDFMLTLGFNYGPNTPAGTIANL
#oth            223132322221111222221122131121312133211212222232213212221332
VNG2358         ::P:::GEPGY::::DENRQ::D::R::Q:E:::::::::::::::D:::::::S::T::
Hbo2816         P:E:V::AENL:YGENGKDH::I::H::W:K:::SKS:::::::::S:::L:::::::S:
hla2627         -------::::-::::::::--:-----:-------------------------------
Hbo0573         :S::TPS::::-::::::::--:F:::::-::T:QE:::L:YGVAL:AY:IN:D:S-RTF

consensus       FGEEGNFNAYGYAPDADLAAMRDAAQTAASRDAAKAAIAEMLAYLSEERPVIFEYNPYNK
#oth            233223113111313322232213112132232223323222221121212212222223
VNG2358         ::T:QS::S::::::R::VG::::::::::::::::K:T:::E::::::::::::::::F
Hbo2816         :S::::::::::T:GK:::::::E::::E::E::VGT:Q::::::::::::::::::::Y
hla2627         ------------------------------------------------------------
Hbo0573         WVPD:G::F:::E:E:PM:DLY:T::S:TDEKTR:E:F:KIF:A::K:Q:TN:LNFSVY:

consensus       YAYRNNVEGM---PADGAFDY-LERWDSEMYFSDGASGR
#oth            211332222211113333211232323232222223111
VNG2358         :::NDS::NI::::DSP:N::YV:ERY::::::::::::
Hbo2816         ::::::::::GQS:P:SH:::QTD::TAK::::::T:::
hla2627         ----------:::--------:-----------------
Hbo0573         N::DK:YM:::::::E:E::::::S:::TSWYLAKQ---