3 genomes BUD2632 3 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_0322 Hbo1157 - - hla0262 - -

Pairwise sequence scores
Consensus score	4131	hla0262	HVO_0322	Hbo1157
2376	hla0262	5499	1229	1238
2634	HVO_0322	1229	4263	1553
2375	Hbo1157	1238	1553	3552

773 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
hla0262         MTRFEPVTDTLLIRSGLSIHRLLRLLVHRFFEPFDSVVDGRVHAVAGLAFELVAVGTTRF
HVO_0322        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo1157         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
hla0262         EDLLAAFLDLLAGRHQPIVGLRVRLFLGLRADLLRALSSLGEALVGVRFRRRDDLVRLRF
HVO_0322        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo1157         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------MFDYQE
#oth            111111111111111111111111111111111111111111111111111111212222
hla0262         SLFDPVEHLWSRHATNRLKLHKRRIRCLRKCARGSADLGGRSRRNVAGIAPLPPT:K::S
HVO_0322        ::::::::::::::::::::::::::::::::::::::::::::::::::::::------
Hbo1157         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::VG:

consensus       PDRHRMARVYAVASAKGGVGKTTTTANLATALAASGADVVVVDGDLGMANLAGSLGVDPD
#oth            22222.11....1..........1.111112..21.1..111.1....1...111..112
hla0262         ::P::::T::::::::::::::::::AV::L::D::::::AI:A::::::::E:V::T:G
HVO_0322        -----::::::::::::::::::S::::G:T::MA:H:::::::::::P::::A::::::
Hbo1157         SE:LD:G:::::V::::::::::::T:::A:::::::::A::::::::::::::::::SS

consensus       GATLHDVLAGEAALEAAVRAGPAGLRVVPGSADLEAFAAADPEGLRDVISALRAAHDYVI
#oth            .1......1.1.2212.122..1.12.1..111.1.1.2.1121.22.21112222.1.2
hla0262         :I::::::::A:DPPD::H:::::::::::A:::::Y:::::S:::E:VA:FDD:-:::F
HVO_0322        ::::::::T::::V:T::YD:::::S:L:::NA:::::T:NAKE:EP:::T:E:SY:I::
Hbo1157         ::::::::::::E::::T:G::H:MT::::::::D:::R::::::H::L::::EN::::L

consensus       IDTGAGLSNDTFVPLGLADEILLVSTTERDALGDTEKTRQLAARLGADVAGVVITRVDP-
#oth            2.1.....2.121..211..21....11.2..........112.1122.1.111..1.11
hla0262         V:A:::::H:STL:::::::T:::::A::S:::::::::::TE:::GS::::A:::L::A
HVO_0322        ::::::::D::::::K::::VI:::::::E::::::::::::D:I::::V:::L::::Q:
Hbo1157         L::::::::::V:::TYV:::::::::G::::::::::::V::::DVP:::A::::::::

consensus       ---DNPNADAVASTLDAGVLARIPEADAVRRAGDAADPLPVHAPDSIATAAYRALAAALT
#oth            1111212211.111..22.1221.1211112.22122.12121.112.111..1.121..
hla0262         TAA:DRPV::::E:::VP::G::::D:::L::VE::Q::::F:::AP::R:::D:TR:::
HVO_0322        :::SK::::V:::L::T::I:VV::SP:I:E:LSTR::VV::S:::::::G:::::E:::
Hbo1157         ::::::QQS::E:::::T::SS::R::V::N::::GE::TTY::G:S:A::::::::D::

consensus       GAAIP----VDGLDAETDNADAEPEPEDAAA----PEANAERAGDADFLDDAGDGAADGA
#oth            .2221111112121211221.22111111.211112222212222222222212122.11
hla0262         ::::DGLGL:::S::::EKT:V:T:N::T::GGAYSG:D:::T:K:EP::E::S:D::DS
HVO_0322        :TPV::::::P:::D:::E:::T:::A:::D::::::P:P:P:P:S::VE:S:::VD:::
Hbo1157         :ESL:::::---------:::SS:M::T::-::::-------------------S:T:::

consensus       G-----------------DAAATSDEDAAAADAEAESEAEKAAEAEEEGESTAEDEPEAD
#oth            111111111111111111.112111112222121211121222111121.1121221111
hla0262         :::::::::::::::::::VTE::R::DSIP::::SD:S:::D:S::I:::E-:VPD:::
HVO_0322        :PAATPDLDSGSDSVADP::::VA:::R:T::P:L:::::PNV:::P:::::V:T::::E
Hbo1157         V::::::::::::::::::::S:::SV:T:GNGAV::DPTSE:A:A:TD:T::T:G:SD:

consensus       AQDEEEIIVADDEDAD-GEPGDERDIIASAAEAPDDPAEADPTDAARASDAAEDADVDKA
#oth            211111111.2122111111112222211221221111111111212122221211112.
hla0262         :::D:D:::::S:Q:GL::::::E:::VA:ESPVE:IE::EA:::EK:--DT:K::TE::
HVO_0322        PNA:T:PEP:V:S:T::DDLAALIPFS::T::E::::::P::::G:D::ES:A:PA::S:
Hbo1157         S:::::::::G:HE::::::::V:--T::DD::S:E::-:::LGD::GV::N:V::::T:

consensus       DDPADDADADPEAADAADDPVDADTDPVGDEAADADDLAAD-----------DEEDIEPA
#oth            12122.122.12.11222111222111.12122.2121211111111111111.122121
hla0262         :TE:T::ES::::--T:V:A::GK:ET::EDHV:G:::E:M:::::::::::I:::L::E
HVO_0322        V::G:::P:::L::::S::::L::S::::::ET:T:P::::LDAVTRGTPAA:::TVAV:
Hbo1157         :E:LI:R:G:TV:::STTE:T---::::DV:::::ES--T::::::::::::::PL::T:

consensus       DDADDSDADADPDAADEDAGAEDSAADEPREAPKADGEGADAPEADEELVAEAEEDAAEA
#oth            122121.21112122.12222122222222222222212222222222211111221111
hla0262         TFD:EG:ST:E:T:G::P::S:S:VESP:D:E::S:::SVSVS:SEP:P:P:::SGPN:E
HVO_0322        ::EVV::V:::T:S::A:PL:::T::::S:S:SS:SV::::::G:::P::::::P:::::
Hbo1157         :S:::::::G:S:DS::Q--------------------------------:DTD:E::T:

consensus       EEADTDADLDADDPFRDDEEGVYTTSLSEDADDMDDDERDDEKKGFFSRFLG-
#oth            1121112221112222.111.111.112122122...1211111.111.11.1
hla0262         T:P:P:DE:AGSV:::::DT:TMN:AF:::D::-:::DD:::NG:::::LF:R
HVO_0322        :SDA:E::P::::SPE:::::::::::V:EVESF::::::EK::::L::::::
Hbo1157         ::::::EGT:::ET--:E:::::::::---::G:::::EQ:::::L:G:::::