3 genomes BUD2636 3 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - - HVO_0826 Hbo0708 - - hla2580 - -

Pairwise sequence scores
Consensus score	2607	hla2580	HVO_0826	Hbo0708
2246	hla2580	2768	1908	2019
2220	HVO_0826	1908	2612	2022
2334	Hbo0708	2019	2022	2622

375 symbols
consensus       -----------------------MAEMEFDFDLLRELTETSGVPGYEDRIRAIVRRELEA
#oth            111111111111111111111112222...111.21...11.......11.21..11111
hla2580         MRNTETGRAFRILRNFVGGVVRVSMSF:::Y::::::::AR:::::::EV:E:::::FAD
HVO_0826        :::::::::::::::::::::::---::::::R:KQ::::::::::::::::L::ED:::
Hbo0708         ::::::::::::::::::::::::::Y::::E::Q::::::::::::::::D::::::::

consensus       RTDRVRTDAMGNVVGTIEGDSDYSVAVAAHMDEIGFMVRHVTDEGFVQLDALGGWDARVL
#oth            21.2.11.1.....1.1..2...1.................1....1.1.1...1.1.1.
hla2580         :A::::::::::::A:L:::::::::::::::::::::::::::::::V:P:::F:::::
HVO_0826        T::S::V:G::::::::::E:::E:::::::::::::::::N::::L:::::::::P:::
Hbo0708         H::K:Q:::::::::::::T::::::::::::::::::::::::::::::::::::::I:

consensus       KAQRVTVHAGAEDLTGVIGSVPPHTLTEEQKEKDDEVEDVYVDIGLDAETVEETVNVGDL
#oth            1....11.2121.1......1.....11...1.111.2.111.2.11..111.1.2....
hla2580         R:::::::-:E::::::::::::::::D:::::::::S::FI:V:R:::A:::L:G::::
HVO_0826        :::::::::ED::::::::::::::::::::Q:EPK:::::::L::P::::::::S::::
Hbo0708         :::::QI:T::G:V::::::P:::::S::::::::::K:L::::::::::AK::::::::

consensus       VTMEQTTVRMGDHVTGKALDDRICLFAILEAAKRIEDPDVTIHFAATVQEEVGLRGATAL
#oth            ..11...11..111....1...1...12......1.1.1..1...........1...1..
hla2580         ::LD:::T::::RI:::::::::::::T:::::::::::::::::::::::::I::::::
HVO_0826        :::::::::::N::::::I:::V::::M::::::::N:E::::::::::::::::::Q::
Hbo0708         ::::::::E:::::::::::::::::S:::::::V::::::V::::::::::::::::::

consensus       GVDLDPDLAIALDVTVANDVPGF-DPADHVTELGAGTAIKLKDSSVITNPKVHRRLRAVA
#oth            ...11....11..1.......111111.1..1..1.11.....1.1.11....1..11..
hla2580         :::I:::::::::::::::::QIGE:::A:::::E:::::::::::::S::::K::T:::
HVO_0826        :::::::::LG::T:::::::::::::::::K::::AG:::::::A:A::::::::::::
Hbo0708         ::::N::::::::::::::::::::AG::::::::::::::::G:::::::::::::D::

consensus       EAEAIDYQHEVLPAGGTDTAGFQNTAGAKPVGAISIPTRYLHTVTESAHEDDVAATIDLL
#oth            .212121.2.1........1....12.........1..........11121..2.1....
hla2580         ::::::H:::::::::::::::::::::::::::::::::::::::T:DG::::::::::
HVO_0826        :DDD:P::M:L::::::::G::::SY:::::::::M:::::::::::V:::::V:Y::::
Hbo0708         :S:GVE::Y::::::::::::::::H:::::::::::::::::::::::VA::D::::::

consensus       TAFLESETGEHDYTL
#oth            1...11.1..1....
hla2580         :::::::S:::::::
HVO_0826        ::::::::::F::::
Hbo0708         A:::DT:::::::::