3 genomes BUD2953 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - pNG7122 - - - - - NP2004A NP6128A HQ3619A

Pairwise sequence scores
Consensus score	3205	NP6128A	NP2004A	pNG7122	HQ3619A
2239	NP6128A	6038	1814	1792	1731
2367	NP2004A	1814	3254	1854	1915
2498	pNG7122	1792	1854	3315	2132
2524	HQ3619A	1731	1915	2132	3290

854 symbols
consensus       -----MRRNRVSRRALLATGAAALGAGLAGC--SGGSGGRDGPT----DT-KIGVLEDRS
#oth            111111333321.13212212112131.1.1111212.13122211121122211..11.
NP6128A         MGPRGTILEKLG:ST:VS::SVGGVG::I:K:::TV::S::D:I::::--:TLA:::N::
NP2004A         :::::::NPT::::K:::S::::A:I:::::::M::N::S::::::::--:-V:I:::::
pNG7122         ::::::N:SS::::QF:GASG:::VT::::::::A:E::TSTD:ASST::L:::::::Q:
HQ3619A         ::::::SD::M::::V:::::VG:::S::::SS::::::G::SE:::S::I:::::::::

consensus       GNFALVGTPKWQASRLAIEEINADGGILGKQIELFDPDPQSDNERYQQLTRRLIRQENVD
#oth            .1.212.11.12.12..11.1.12..12.221.2211..1..12..11..32213122..
NP6128A         :K::EL::S::::::::V::L:ES::A::RK:::I::::A::VK::R:::TEILEERD::
NP2004A         :::Q:N::S::::T::::::::E::::::EEV:IV::::::::::::E::E:::L:DQ::
pNG7122         :::::::D::AK::M::::::::N:::D:::::T:QR::::::Q:::E:::TA:NE::::
HQ3619A         :::S:::::::R::K:::D::::::::M::::::::::::::::::::::S:::::::::

consensus       ALWAGYSSATREAIRPIINRNEQLYFYTTQYEGGVCDEYTFAVGPTARQQLGAVLPYLVE
#oth            .1....1.11..11..111222......1......1.221.21.2.......2.2..122
NP6128A         :I::::A:SE::VV:::T:AHR::::::N::::::::R:::P::A::::::::::::::S
NP2004A         :::::::::::::::::::DED:::::::::::::::DTI::::S:::::::::T:::AD
pNG7122         ::::::::::::::::::D:::::::::::::::::::F:::::::::::::I:::::::
HQ3619A         ::::::::::::::::T:D::::::::::::::::A:::::CM:::::::::S:V::MI:

consensus       EFGPDIYTIAADYNFGQLSADWVKVIAAENDANVIGEEFIPLSESSFGSTINRIQAADPD
#oth            21.21.11........1..2...211.3..11112.1.11..1122.212121.121...
NP6128A         :Y::K:F:::::::::H::S:::EIL::::::E:::T::V::::T::EWLVD::E:::::
NP2004A         QY:E:::I:::::::::::G:::N:::E::GY:IV:::Y:::D::D:S:V::::::E:::
pNG7122         :::::::::::::::::::::::::L:N::::::L::::::::::::::::::::E::::
HQ3619A         N::S:::::::::::::::::::::::D::::E::::::::::VQN:::::SN::D::::

consensus       FVMSMLVGANHASFYRQRASADLDIPIGTSTAMAQGYEHKRLEAPALADVYAGVNYMEEL
#oth            .1.11...1..32.23112121.32.1....2...121.2.1111.3211.1.11....2
NP6128A         ::::::::D:::E:F:EK:TR::SM::::::::::AF::::Y:P::F:::::::::::::
NP2004A         :I:::::::::EN::D::D:N::M:::::::T::::H::I:Y:PN:VT::::::S:::::
pNG7122         :::::::::::T:::E:K:::G::V::::::::::::::R::D:::M:NI:::::::::V
HQ3619A         :::AI::::::S::WN::T::G:E::M::::V:::::Q:::::::::K:::G:F:::::I

consensus       PTDRNT---NFVERFYDMFPDANYLNQEAQNNYFSIYMYKKAVEEAGTTDQDAVIDVLES
#oth            21321211231.2111122...3.2.1.121..1.211112...2...11.21.112..1
NP6128A         S:QE:::::T::::::E:::::D:I::::::::V::HL:A::::A::::::::::EQ:::
NP2004A         GDL:EG::E::::D:::RW::::::::::::::::V::W:E:::::::F::::::::::E
pNG7122         :::S::GDGG::D:YFE:Y:::P:::E::ET::::T::::::::Q::::E:PE:::A:::
HQ3619A         ::S::E:::DY:S:Y::K::::G:A:E:SI::::::::::Q::::::::::E::R:::::

consensus       GIEI---RAPEG----RIALDGATHHITHNMRIARADEDHNIEFDAERRIPETFLSETV-
#oth            .31322231.11111121321.11..22.3.11111.22.112233213.212..11111
NP6128A         :LSF:::D:::::::::V:I:::::::N:T::::::::::::::FN:Q::D:::::Q:::
NP2004A         :V:M:::N::S:::::::E::::::::::Q::V:H:::N:D:S::::QE:GPS::R:E:E
pNG7122         :::LGTEE:::APEGET:R:::::::VD:H:W:M:::D:::V:AVEN:Q:::::::::A:
HQ3619A         :M::TGD:S:::::::D:SFQ:PV::M:::::VM:C:AE:::TVEDQ:K:::Q:::::::

consensus       ---GCDLREEAE--TTQYTPA---------------------------------------
#oth            111.11.222321111.12.1111111111111111111111111111111111111111
NP6128A         :::::::::V::::::::R::LFHQQGTFDSMHDALEDRVQDAHESEKLREQLEARTQAY
NP2004A         GGD:::::A:SK::::::E:::::::::::::::::::::::::::::::::::::::::
pNG7122         :::::N:P:NP:::Q:::::V:::::::::::::::::::::::::::::::::::::::
HQ3619A         ::::I::SG:DDGM:K:F::V:::::::::::::::::::::::::::::::::::::::

consensus       -----------------------------------------------DYYDDAAS-----
#oth            111111111111111111111111111111111111111111111111222123211111
NP6128A         SDAMRAAAEGDLTTRMSTGANNEALAVIAEEFNEMIAEMERTLADIGEFA::V::ASREV
NP2004A         ::::::::::::::::::::::::::::::::::::::::::::::::V:G:ILE:::::
pNG7122         ::::::::::::::::::::::::::::::::::::::::::::::::::EE:E-:::::
HQ3619A         :::::::::::::::::::::::::::::::::::::::::::::::E:F:E:G::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
NP6128A         TTSTDEVRATSESVASSIDQISDGAADQNESLQVVNDEMSDLSATIEEVAATTDEVADVA
NP2004A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG7122         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3619A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
NP6128A         AKTAAAGSHGQEAATDAIAGMNETEQKAEQAVDAIHELEAEVTEIDALIDQISEIAEQTN
NP2004A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG7122         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3619A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
NP6128A         ILALNANIEAARTGGDGESNGDGFAVVANEVKELSEEVKQAAESAESRVEAIQERTDRST
NP2004A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG7122         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3619A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
NP6128A         TAVEATSERIAGASEQVTEAVEALEEIAAYADETNDGIQEISNTTEDQATSTEETVSMID
NP2004A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG7122         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3619A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
NP6128A         EVASISEETTTEAESVAAAAEEQSASLAEVSASATELSERAAELSEAISRFEVGADLDDD
NP2004A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG7122         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3619A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       --------------
#oth            11111111111111
NP6128A         AVDTSGAAEPGVSD
NP2004A         ::::::::::::::
pNG7122         ::::::::::::::
HQ3619A         ::::::::::::::