2 genomes BUD3132 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi - pNG1017 pNG2044 pNG3054 pNG4027 - Hbo3717 - - - - -

Pairwise sequence scores
Consensus score	4121	Hbo3717	pNG4027	pNG1017	pNG2044	pNG3054
776	Hbo3717	3165	629	727	727	744
2800	pNG4027	629	4063	2750	2747	2754
4043	pNG1017	727	2750	4108	4092	3652
4031	pNG2044	727	2747	4092	4107	3644
3721	pNG3054	744	2754	3652	3644	4118

555 symbols
consensus       ----------MSQNNP------KSEQDGFTEKTRQGAQIIHGADPHG---------KWPD
#oth            111111111111234.1111112322112.131211222221311121111111113222
Hbo3717         ::::::::::::TQ::::::::----TDT::TK:KEEILAEFP:::TTSKQYTGDQRCH:
pNG4027         MPRGNYRYQPATAAH:LMLIGEDPDG::Y:VR:Q::QP:VI:RPAPS:::::::::QY:S
pNG1017         ::::::::::::::L::::::::::::::::::I:::::::::::::::::::::::::T
pNG2044         ::::::::::::::I::::::::::::::::::I:::::::::::::::::::::::::T
pNG3054         :::::::::::::RK::::::::A:::::::Q::::::VV::C::P::::::::::D:D:

consensus       DAEEIRNRFDIPAFDPEAFYPREGA-----ALSG-------VYPDFLVHIENAADGPSTV
#oth            .122.131.2..11111.1.2111.11111.11.111111111.1212.11222.1121.
Hbo3717         :FWD:KRA:G::KMEWD:T:TE:E:EGKAY:EA:ERKLRKKLL:NIIF:DWDPD:HQLS:
pNG4027         ::H:::Q::N::::::::::R:T::::::::::::::::::::::M:I:::D:::::D::
pNG1017         ::::::::::::::::::::::::::::::::::::::::::::::::::::S:::::::
pNG2044         ::::::::::::::::::::::::::::::::::::::::::::::::::::S:::::::
pNG3054         :::M::T::::::::::::::::::::::::::::::::::::::::::::S:S::::::

consensus       NSPGASLTMVEAPKGSGKSTAADQFATYQMEHNDERIVRNGRQKSSDWRRLADWTTLWLP
#oth            211111111211.1.....111111.111..1.2.1111111121.1.11211.1111..
Hbo3717         ---:GTDWLAVG:P:::::NL:LWL:VRL::A:N:KVIWRASTSR:E:LPF:P:ARVC::
pNG4027         T::K::::LI:::::::::::I:::::::::::G:::::::::Q:::::::R::::::::
pNG1017         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG2044         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG3054         ::::::::::::::::::::::::::::::::::::V:::::::::::::M:::::::::

consensus       SGVDVDGRWM---ETVDRDDPDPDELCRDVRYYSDVHELVARLQDHPKGTYNVVFPDPYF
#oth            2.11121.1111111111121111.11.2.11.2.132.222.12111.111..1...21
Hbo3717         K:::IEA:FVPKDP:QEGFEV:LE:IV:E:VR:R:PVH:NHD:LKP--:QFH::Y:::KM
pNG4027         E:I::N::::::::A::::A:T:E::V:A::::T::FD:IEQ::::::::F:::Y:::L:
pNG1017         :::E::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG2044         :::E::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG3054         ::::::::::::::A:::::::::::::::::::::L:::E:::N:::::::::::::::

consensus       RGCEEALSTADATVQQPEFIPKNEPNPTPASHWWFGFLAARTFDGVRVDGDGDRNWMTAH
#oth            .212212222121212131312212211.22.....111..1121311121.211.1122
Hbo3717         :RLQ:IYEND----:EKQYDGLEFSEDD:LN:::::WMH::I-------AE:PHH:SSIM
pNG4027         ::::R:MAIP:T:TE::K:T:QG:DK:::VV::::::::::::R:T:::S::::::::VY
pNG1017         :::V::::::::::::::::::::::::::::::::::::::::::::::::E:::::::
pNG2044         :::V::::::::::::::::::::::::::::::::::::::::::::::::E:::::::
pNG3054         :K::D::::::T::EH:T:V:::::::::::::::::::::::::L:::S::::::::::

consensus       IDEFGMLAPESAPGGESGHWTHQCVQIMADIAKEMRSAGLSLVGYGHHEEDVHNHWLKEF
#oth            1..1.11...11211.21.1111112112.21111.11.2.11121.1.1.1.1111111
Hbo3717         F::I:DI:::A:RND:YA:--Y:K:ELLK:CWVDA:KY:H:IFAF::S:A:I:SMIRRKI
pNG4027         :::::::::::TS:::A::::YE::E::S:T::::::::V::::AA::::::::::::::
pNG1017         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG2044         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG3054         ::::::::::::::::::::::::IK::::::::::::::::::::::::::::::::::

consensus       DFWVELSNHDRGNRTTKAEAPKPFRDIEQDQDLLSKRPKGFGLCYTANRFSEFQFSDLGY
#oth            121.1111221111111112111..22211111211.12.2111112211....121111
Hbo3717         RWR:TMNGTANPTNSGDVVG---::RVPMED:IM:S:DV:MFMPFSE---::::YPPVKA
pNG4027         :Y::::::RE:P:::::::T:::::GLK:::N:FAS::P:Y:::::ES:::::::T::::
pNG1017         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG2044         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG3054         ::::::::::::::::::::::::::L:::::::::::::::::::GS::::::::::::

consensus       PHDTPEFQLRLGIPEAVDVPTSDDGGMIVEDLQVATDDEGQPTILKEYRAADGAVHELRV
#oth            1.21111121121.2221232111311111111.11123211112311212211111111
Hbo3717         A:----------::SPI:MT-----------:K:S-------------------------
pNG4027         ::E:::::F::SV::SAAEDE:::A------V:::::EA:::::VE::T:V:::::::::
pNG1017         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
pNG2044         ::::::::::::::Q:::::::::S:::::::::::::::::::::::::::::::::::
pNG3054         ::::::::::::::SS:::S::::::::::::::::::DD:::::N:::::G::::::::

consensus       LAPGRGIIDISGDEPEPLEVLSSPYPDAEFPENPIKTTQTHYDIMFKPDANAEIVAARIP
#oth            111131211121221132132111.11231122123212321222132223321111122
Hbo3717         ------------------------:A----------------------------------
pNG4027         ::::S:L:::G:::::IV:SP::::::GS::DS:LRE:AEG:ELL:ERA:GEI:::::VS
pNG1017         ::::::::::::EK::::::::::::::::::::::::::::::::::::::::::::::
pNG2044         ::::::::::::EK::::::::::::::::::::::::::::::::::::::::::::::
pNG3054         ::::D:::::::::::V::Q:::::A:GT::::::T:::N::::::N::SST::::::::

consensus       RRTGPGTTTEVEADE
#oth            221111211112112
Hbo3717         ---------------
pNG4027         HH-------------
pNG1017         :::::::::::::::
pNG2044         :::::::::::::::
pNG3054         ::::::A::::M::D