[BQ] (AcuC) COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein 9 genomes BUD0654 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0136 rrnAC2299 HVO_0522 Hbo0998 Hmu0095 Hut2968 hla0413 NP0318A HQ1437A

Pairwise sequence scores
Consensus score	2646	Hut2968	NP0318A	VNG0136	rrnAC2299	Hmu0095	hla0413	HQ1437A	HVO_0522	Hbo0998
1777	Hut2968	2616	1488	1520	1655	1630	1512	1459	1586	1552
1850	NP0318A	1488	2613	1649	1625	1589	1607	1639	1648	1658
2005	VNG0136	1520	1649	2666	1761	1703	1715	1658	1753	1699
2039	rrnAC2299	1655	1625	1761	2627	2044	1686	1654	1793	1729
2020	Hmu0095	1630	1589	1703	2044	2625	1658	1612	1756	1673
2093	hla0413	1512	1607	1715	1686	1658	2592	1828	1920	1891
2007	HQ1437A	1459	1639	1658	1654	1612	1828	2609	1839	1951
2167	HVO_0522	1586	1648	1753	1793	1756	1920	1839	2644	2033
2121	Hbo0998	1552	1658	1699	1729	1673	1891	1951	2033	2605

340 symbols
consensus       MRFGYSEACLEHDTGPRHPESADRLRAIRRGLAKRHGVEYVDADPADRDAIAAVHDADYV
#oth            .3..1114..2..1.5....21......2.2.2331112.4326413444162..152.3
Hut2968         :K:::R:I:::::::S:::::P::::::Q:T::DSAN::::P:TAIP::::W::::H::L
NP0318A         :::::R:::::::::S::::T:::::::::::KR::::::R:GRL:E::::E::::::::
VNG0136         ::::F::::::::P:V:::::P::::::K:::Q:::::T:E::PD::LSD:T::::P::A
rrnAC2299       :N:::R:V::D::::::::::P::::::::A:KEN::::::A::N::L:LVR::::T::I
Hmu0095         :N:::R:V::D::::::::::::::::::::::EY::::::A:GD::EEL:CK:::P:::
hla0413         ::::::DR:::::::E::::NP::::::::::::::::::AE::::T:EEVV:::::E::
HQ1437A         :Q:::::I::A::::N::::T:::::::::A::::::AS:I:PK::TDTD::S:::TE:I
HVO_0522        :Q:::::T::D:::::::::T::::::::::::::::::::::S::EKSTV:::::DG::
Hbo0998         :Q:::::T::A::::K::::T:::::::::A::::::::::E:::::DA:V::::EEG::

consensus       DEIRAFCADGGGNWDPDTVAVEDTWDAALASAGLAQWAARAALDGADGRDTPFSLGRPPG
#oth            31333.244...2..1..1.2141.3.122..1..51.233.23.22113...12.....
Hut2968         EDV:Q:::N::::::A::::::A:::::V:::T::A:::DE::E::::CE::::::::::
NP0318A         AD:E::M:::::T::A::::::E::E:::::::::S::VDE:IG:::::Q:::AI:::::
VNG0136         T:V:S::ER:::S:::::A:T:S::P:IR::::::MD:ID::::::::::::::::::::
rrnAC2299       A:F:E::D:::::::A::::::E::::::::::::V:::E:::::NT:::::::::::::
Hmu0095         E::K:::QE::::::A:::::::::K:::::::::E:::LS::::D:::E:::A::::::
hla0413         ::LE::V:::::S:::::::S:G:::::::::::::::::S::N:::::::::A::::::
HQ1437A         T:::E::EC:::::::::::SI::::::::::::::::::V:VN::S::Q::::V:::::
HVO_0522        ::FHE::R::::::::::::::AS:::::T:::::E:::::::::D:::N::::::::::
Hbo0998         ::::S::EE:::::::::::S::::::::V::::::::::::VE:::E::::::::::::

consensus       HHAVEDDAMGFCFINNAAVAAQTALDDDG--ADRVAIFDWDVHHGNGTQDIFYDRGDVFY
#oth            ...2611......31..11.114212346222131111............11..23112.
Hut2968         :::::::::::::L::::I::EH::RR::::V:::::L:::::::::::::::::S::Y:
NP0318A         :::EI:E::::::F::::::V:Q:::AEDSGV:SAV::::::::::::::::::SD::::
VNG0136         :::IT::::::::V::::::::H:::AH:::L::::::::::::::::::::::::::::
rrnAC2299       ::::G:::::::::::::::::A::EA:-::::::::::::::::::::::::::S::::
Hmu0095         ::::A::::::::VD::V::::S:::EG-::::G:::::::::::::::::C:::D:I::
hla0413         ::::P::::::::F:::::::::V:::GA:::::::V:::::::::::::V:::::::L:
HQ1437A         ::::V::::::::::::::::::LI::PSSDV:TA:::::::::::::::::::NAN:L:
HVO_0522        :::::::::::::F::::::::AVI::GL:::E:::::::::::::::::::::::::::
Hbo0998         :::::N:::::::::::::::::VI:::ELD:E:::::::::::::::::::::::::::

consensus       ASIHEDGLYPGTGEVDETGTGDGAGTTLNVPLPAGAGDADYLAAIDEVIAPAIERFDPDL
#oth            2.3..3..1.1..32511.532132221.21254.11111.433443521.233512...
Hut2968         ::F::E:::::::D:G:::ADA:R:R:::::F:S:S:::::::VHR::V::EF:N:E:::
NP0318A         :::::R::F::::D:L:::GP:ARN:I::::::G:S:::E:R:VMEQLLR::LD::E:::
VNG0136         T::::::::::::S:AQ::DC::::::::L:F:T:::::::A::V:DF:::::RA:::::
rrnAC2299       :::::::::::::DIS::::::AD::N:::KYKP::DT:::::::::C:::::RDY::::
Hmu0095         :::::E::::::::::::::::::MR:::::YDP::DTV:::::V::L:::E::S:::::
hla0413         ::::::::::D::AL::::HDE:::::V:L::S:::::::::Y:::::V::::K::::::
HQ1437A         V:T::E::::::::IE::::::AE:::::I::S::::::E::HM:NTI:R:V::S:N:::
HVO_0522        T::::::::::::::::::E:::E:S::::::H::::::::VYSF::A::::V:::::::
Hbo0998         ::L::G::::::::I::I:E:::E::::::::E::::::::ELV:S::LR::L:Q:::::

consensus       FIVSAGFDAHRHDPISRMRVSTEGYALLTDRVRDLADRCDAGLAFVLEGGYGLDTLADGV
#oth            321.......31.....121111..151133225233441.22221.....1.11.2211
Hut2968         I:::::::::EN::::::L:::A::GV:AE::HE::::I::::::::::::::E::SA::
NP0318A         :V::::::::K:::::::::T::::GY::AT:::I:ADH::P::::::::::::P:::S:
VNG0136         :V::::::::H::::::LHL::::::M::::::RISA:T::P:::::::::S::::::::
rrnAC2299       LLI:::::::E::::::::::::::GAM:::M:S:T:A:::A:GII::::::::::S:S:
Hmu0095         LL:::::::::::::::::::S:::G:::Q:M:::T:::::::G:::::::S::::T:SL
hla0413         V::::::::::::::::::::S:::::M:::I:TVT:NIE:ANSY::::::::::::E::
HQ1437A         ::I::::::::::::::::::::::::::::::S::NDV:::::::::::::::::::::
HVO_0522        ::::::::::::::::::::::::::M::EC:QE:CEET::AI:::::::::::::SE::
Hbo0998         I:I:::::::::::::::::::::::Q:::S::AI:NDV:::::::::::::::::SE::

consensus       STVHETFDGRTPMEPDDDPDEKARDLLDDLRDAH-GFGS-
#oth            431..211.2515532332324546243423442132333
Hut2968         REI::VLN:EHADSIEPA:TDGGQNV::S:VYQ-:::::R
NP0318A         GI:::I::::E::::GG:VRS:SKRVIN:V:::::DL--:
VNG0136         ::::::::::D:T::E::VSDSV:::FERV::T:QA:::T
rrnAC2299       T::::V:::YQ:::::::VSDD:::V::::A:Q-:::::K
Hmu0095         T::::V:::YQ:SQ::GSVS:D:::V::A:V:Q-:::::T
hla0413         :M::::::::::VGD:::::::TES:VTE::ELL:DL--:
HQ1437A         :I::::::::::LAH::E:::EVKT:A::I:TI::NIA-:
HVO_0522        A:::::::::IA:D:EE:::::NVE:V::V:A::::L:AK
Hbo0998         AI::::::::::::IEE:H:::TEAIIE:VL:::::IDG: