[E] (HisB) COG0131 Imidazoleglycerol-phosphate dehydratase 9 genomes BUD0725 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2295 rrnAC2555 HVO_2986 Hbo1535 Hmu2999 Hut2840 hla0591 NP2258A HQ1026A

Pairwise sequence scores
Consensus score	1468	VNG2295	HQ1026A	Hut2840	rrnAC2555	Hmu2999	NP2258A	Hbo1535	hla0591	HVO_2986
1178	VNG2295	1489	1058	1127	1138	1143	1103	1062	1037	1069
1200	HQ1026A	1058	1562	1068	1057	1038	1150	1170	1083	1160
1281	Hut2840	1127	1068	1452	1232	1250	1187	1150	1163	1168
1264	rrnAC2555	1138	1057	1232	1474	1318	1149	1152	1137	1182
1241	Hmu2999	1143	1038	1250	1318	1463	1166	1174	1132	1132
1307	NP2258A	1103	1150	1187	1149	1166	1469	1205	1122	1208
1299	Hbo1535	1062	1170	1150	1152	1174	1205	1531	1201	1248
1223	hla0591	1037	1083	1163	1137	1132	1122	1201	1486	1246
1306	HVO_2986	1069	1160	1168	1182	1132	1208	1248	1246	1484

210 symbols
consensus       -----MTD--------RTAAVTRETAETDIEVTLDIDGDGESTVDTGIGFFDHMLEAFAK
#oth            1111111122222143.2..21.1.2..2131..22....12211..1.......32.11
VNG2295         :::::::::::::::::::::::::::::VA::::L:::::H:::::::::::::A::::
HQ1026A         MTEDTE:SSTGAGADD::::IS::::::T:N:::AV:::::A::::::::::::::T:::
Hut2840         :::::::::::::::::::::::::G:::::::::L:::::::IE::::::::::D:::T
rrnAC2555       :::::::::::::::::::::::T:::::::::::V::::D::I:::::::::::DS:ST
Hmu2999         :::::::::::::::::::::::::::::::::::V:::::::::::V:::::::DS::T
NP2258A         ::::::::::::::::::::A:::::::E::::::L::::::::::::::::::::::::
Hbo1535         ::::::S:DADSDATS:::::S::::::T:::::T:::::DA:::::V::::::::::::
hla0591         ::::::S:::::::HE:A:::S:::S::T:DL::A:::::D:E::::::::::::SS:::
HVO_2986        ::::::S:::::::AD:R:::S::::::T:D:::A:::::DAV:::::::::::::::::

consensus       HGLFDLTVRCDGDLDIDDHHTVEDVAIVLGEAFTEALGDKRGIVRYADRRVPLDEAVASV
#oth            .....1..3....131........11.31.32242.111....3.1...4........3.
VNG2295         :::::V:::::::::V:::::::::G:A::A::S::V:E::::Q:F::::::::::::::
HQ1026A         :::::::::::::::::::::::::G::::KS:NN:::E::::::::::S::::::::T:
Hut2840         ::::::::::::::AV:::::::::::T::::V:::::E::::D:F::::::::::::T:
rrnAC2555       ::::::::Q::::::::::::::::::T:::::::::D:::::R:F:::K::::::::::
Hmu2999         ::::::::H:::::E::::::::::::T::::LA::::E::::R:F::::::::::::G:
NP2258A         ::::::::::::::::::::::::IG:::::CLAD::::::::::::::A::::::::D:
Hbo1535         ::::::::N:::::E:::::::::::::I:D::S:::::::::::::::Q::::::::G:
hla0591         ::::::::N::::TE::::::::::::C:::::D:::::::::R::::::::::::::::
HVO_2986        ::::::::Q:::::H::::::::::::::::::::::::::::::::::K::::::::::

consensus       VVDVSGRPYFEFDGEFSQPQVGEFTSDMARHFARSLAMNAGLTLHAGVE-GENAHHEVEA
#oth            11.11..1413.2.4...341.22..3..4..4411231122...43121.2.....2..
VNG2295         :::::::AVY::::G::::T::GL::R::A::W:TF:TH:AV:::C::D::::::::I::
HQ1026A         IA:I::::H:::S:S:::::I:G::::::::::Y:FT:HSEI::::SI:::I::::::::
Hut2840         ::::::::::::G:::::AT::::::V::K::L:::::::::::::S:::::::::::::
rrnAC2555       :::I::::::::::::::AS::GM::H::K::C:::S::::::::C::D::::::::I::
Hmu2999         ::::::::::A:::::::GR::GL::H::K::C::::T:::::::VE:D::::::::I::
NP2258A         ::::::::R:Y:::A::::YI::::::::::::E:::L:::::::LSI::::::::::::
Hbo1535         ::::::::::D:::::::E:I:D:::::::::GY::::H::::::TEIR::::::::A::
hla0591         ::::A::::Y::S:::::ES::::::V::D:::L:::H::::::::AI:T:D::::::::
HVO_2986        ::::::::F:::S:D::::Y::::::H::E:::M:::::::::::::::::D::::::::

consensus       LFKALARALDDATRIDPRR-SDTPSTKGEL
#oth            ...211.21.1..12.4..12121....2.
VNG2295         :::GVG::V:::::::Q::AGE::::::D:
HQ1026A         :::S:::T::E::QL:::::G:::::::::
Hut2840         :::G::::::::::::D:::A:A:::::::
rrnAC2555       :::S:::S::::::::E:::::VA::::::
Hmu2999         :::G::::::::::::E:::::VA::::::
NP2258A         :::::::S::::::V:D:::::::::::::
Hbo1535         ::::::::::::::V:::::::::::::::
hla0591         ::::::::::::::L:G:::::::::::::
HVO_2986        :::::::S::::::V:::::::::::::K: