[E] (TrpC) COG0134 Indole-3-glycerol phosphate synthase 9 genomes BUD0390 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0305 rrnAC1886 HVO_0787 Hbo0748 Hmu0823 Hut1869 hla1974 NP3166A HQ1159A

Pairwise sequence scores
Consensus score	1850	HQ1159A	VNG0305	HVO_0787	Hbo0748	NP3166A	rrnAC1886	Hmu0823	Hut1869	hla1974
1302	HQ1159A	1975	1010	1156	1274	1117	1165	1163	1127	1163
1301	VNG0305	1010	1843	1080	1140	1197	1133	1111	1101	1175
1358	HVO_0787	1156	1080	1735	1358	1223	1189	1147	1128	1193
1489	Hbo0748	1274	1140	1358	1886	1243	1271	1218	1189	1296
1424	NP3166A	1117	1197	1223	1243	1831	1327	1184	1180	1233
1501	rrnAC1886	1165	1133	1189	1271	1327	1974	1458	1274	1335
1464	Hmu0823	1163	1111	1147	1218	1184	1458	1933	1317	1284
1382	Hut1869	1127	1101	1128	1189	1180	1274	1317	1898	1319
1507	hla1974	1163	1175	1193	1296	1233	1335	1284	1319	1963

286 symbols
consensus       -MDDSEELAPAVRSILSAARER--GGGDGRVSVDARSLPDAFAAAEAAGRVPVIAEVKPT
#oth            13343522224.21..41.24.1141345313.3121143.3441122.13.311.2...
HQ1159A         MDASE:S:::::Q:::T::KQ:::A::TS:C::::T:FQS:IS:T::::QT:::::I:::
VNG0305         :::::SS::SP:Q:::A:::R:::DPPTR:CT:S:::::A:LHS:A:D::T:I:::::::
HVO_0787        :----------::A::E:::::::P::ET::::::::F:E:V:ET:::::::::::::::
Hbo0748         MNASEDS:::E:::::D:::::::P:::EP:A:T:::F:::V::T:::::I::V::::::
NP3166A         :::T:G::S::::::::::E::::D::ET:CT:::::::::LD::ADG::A:::::L:::
rrnAC1886       :::::::I::::Q:::D::::::::::GD::::TPK::::::E::AD:::T::V::I:::
Hmu0823         ::G::::I::::E:::AT::::::::A::::D:EP:::T::::D:::D::::::::::::
Hut1869         :::A:D:I::D:::::::::D:::::AS:T:D:T::::SA::DR::RD::::T:T:::::
hla1974         ::::QT::::::::::::::N:ATE:RS:E:A:EP:D:RA::DR:::D::::L:::::::

consensus       SPTTDGERTDDPVELAREMVAGGAAALSVLTEPEHFGGSTETLRRIREAVDVPVLRKDFI
#oth            ...1314142..12..43..11..1.1......3..1..322.221.31.2..1.....2
HQ1159A         ::::::K:D::::A::SA::E:::T::::::::::::::V:::AQ::NV:E::I::::::
VNG0305         :::::T:HSG::A:::::::::::::V::::::H::D:::DA::A::D:::::::::::L
HVO_0787        ::::E:V:E:::::::::::::::T::::::::::::::A:S::::::::::::::::::
Hbo0748         ::::A:::::::::::::::::::T::::::::D:::::V:S:::::::::::::::::V
NP3166A         ::::::::::::::::E::::::::::::::::::::::::::::V::::S::::::::L
rrnAC1886       :::A::::A::::D::QQ::E::::::::::::D::::::A::E:V::::::::::::::
Hmu0823         :::AV::::E:::A::EQ::E::::::::::::::::::AA::A:::::::::::::::V
Hut1869         ::::E:RHDG::::::TA::EN:::::::::::::::::P:::A:V:A:::::I:::::V
hla1974         ::::E:T:E::::A::QG:::::::::::::::A::::::D::E:V:::::::::::::L

consensus       LHEAQLDAVEADVVLLIARFLG----DDLADLLTAARDRGFQVLVEVHTRDELARALDAG
#oth            24.4...1.21.31...1..13322121.531351.22....2...2.325.244.2211
HQ1159A         V::S:::::A::MI:::::::DRPET:S:EE:YNV:QN::::P::::::::::E::IEI:
VNG0305         :T:P:::::A::A::::::::::::::::G:M:A::::::::A:::::SPR:::::V::D
HVO_0787        MN:::::V:QS:L:::::::V:::::E::PA:VE::::::::P:::::::E::TA::A::
Hbo0748         VN:S::::::S:L::::::::::::::::S::V:::KE::::P:::::D::::G::::::
NP3166A         :R:::::::AS:::::::::V-:::::::DG::A:::E:::::::::::PG:ART:::::
rrnAC1886       :::N:::V:::::I:::V:::EADGT:::::::::::E::::::::T::AA:VEK:::::
Hmu0823         :::E:::V:::::I:::V:::DEPGTG::::::S:::E::::::::T::A::::::VE::
Hut1869         :::::::V::::L::::V:::EEDGT:::E::ID::::::::::::A:A:S:V:A:V:::
hla1974         VA:S::::::S:::::::::V::::::::P::::::::::::::::::D::::EH:::::

consensus       ADIIGVNNRDLAELAVDLGTFESVAPHVPD----DVTLIAESGIQTPADVRRMRAAGADA
#oth            .3.1.1.....24.5.1.4..14111421211112.1.2....151431132..4....1
HQ1159A         :S:::::::::GR:::T:Q:::QL::::::::::::::::::::K:IEH:QQ::::::::
VNG0305         :::::::::::TA:T:::D::GA:::EA:A::::::::V:::::A::T:A:T:::::::G
HVO_0787        :::V:I:::::GK:E:::::::EL::EA:E::::::L:V::::V::VD:A::::E:::::
Hbo0748         ::::::::::::T:::::E:::::::::::::::::::L::::VTSAE:A::::::::::
NP3166A         ::::::::::::::S:::S:::::VES::ELRDGS:::::::::E:RE::T:::S::::G
rrnAC1886       :::::::::::G::::::::::A:::DI:E::::::::::::::::AD::T:::D:::::
Hmu0823         :E:V::::::::K:::::D:::R:::DA:E::::G:::V::::::S::::A:::R:::::
Hut1869         :E::::::::::K:D:::E:::::::A:D:::::::::::::::E:::::Q::::::::G
hla1974         :T::::::::::::V:::::::::::::::::::::::::::::GS::::::::::::::

consensus       LLVGSAIMD-------GDVRANTRRLTTA-----------TET-T-
#oth            ..1.1...1121211111.441.33124311213323442122432
HQ1159A         ::I:T:::H::::::::::QT::::F::V::TDTDIQDTT:::H:S
VNG0305         :::::::::::::::::P::DT::::V:::::::::::::---:-:
HVO_0787        ::::T:::::::::::::::Q::ET::Q-:::::::::::---:-:
Hbo0748         ::I:T::::::::::::::::::D:FSN:::::::::TAK::LSE:
NP3166A         ::::::::::::::::::::E::E:::DV:::::::::::---:-:
rrnAC1886       ::I::::::HDAA:::T::E:::::::R:::::NTDAVET:T:D::
Hmu0823         :::::::::HGAPAEET::T:::::::::::::::::::::T:HE:
Hut1869         ::I::::::::::::::::A:::QA:::P::::::::::::::PNQ
hla1974         :::::::::::::::::::E::::E:VR:EADDESDTRDT:::P::