[H] (PDX2) COG0311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis 9 genomes BUD0591 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2598 rrnAC2369 HVO_0436 Hbo1069 Hmu0108 Hut2109 hla0177 NP0464A HQ1301A

Pairwise sequence scores
Consensus score	1464	NP0464A	hla0177	HQ1301A	rrnAC2369	VNG2598	Hut2109	Hmu0108	HVO_0436	Hbo1069
1099	NP0464A	1415	1010	988	990	1023	954	1006	1029	1055
1199	hla0177	1010	1472	1008	1070	1022	1057	1036	1078	1106
1140	HQ1301A	988	1008	1523	1070	1104	1066	1026	1135	1119
1220	rrnAC2369	990	1070	1070	1472	1100	1118	1139	1134	1087
1214	VNG2598	1023	1022	1104	1100	1515	1109	1107	1100	1155
1190	Hut2109	954	1057	1066	1118	1109	1443	1104	1081	1082
1226	Hmu0108	1006	1036	1026	1139	1107	1104	1475	1140	1133
1254	HVO_0436	1029	1078	1135	1134	1100	1081	1140	1505	1183
1258	Hbo1069	1055	1106	1119	1087	1155	1082	1133	1183	1509

207 symbols
consensus       -MTLTAGVIAVQGDVSEHAAAIERAAAAHGEDAEVVEIRDAGVVPDCDVLLLPGGESTTI
#oth            12224...2......1..12.112.132.244321311.52.51.1..2..3......1.
NP0464A         :-M:K::::::::::A:::D::R:::DR::::CT:ES::S:::::E::L:::::::::::
hla0177         :--MQ::::::::::A:::::V:N:::::::P:::::V::::I::::::::M::::::::
HQ1301A         :-MIQ:::V:::::::::::::R::GES:SISV:I::::QS::::::::::I::::::A:
rrnAC2369       ::::R:::L:::::::::GD:::::::::DRT:::::::E::L:::::::::::::::::
VNG2598         ::::::::V:::::::::::::R:::D:::QP:D:R:::T:::::E::::::::::::A:
Hut2109         :::I:::::::::::::::T:V:A:::::DQTT:I:::::S:R::::::::V::::::::
Hmu0108         :::::::::::::::::::T::::::R:::::::IH:::HS:T::E::A:::::::::::
HVO_0436        MT::R:::V::::::::::D:V::::E:::V:::I::::SD:L::::::::M::::::::
Hbo1069         :-MIH:::V:::::::::::::R:::D::::NVD:::::QS:HI:::::::I::::::A:

consensus       SRLLRREGIDEEIRAHVAAGKPVLATCAGLIVASRDAKDDRVETLDLLDVSVDRNAFGRQ
#oth            ...142...14..3311211..2........1211.13....32.222112.1.......
NP0464A         ::::AE:::::::E:FA:::::L:::::::::::::::::::S:::I:::::::::::::
hla0177         :::I::::::::::E:::S:::::::::::::C:::::::::DA:G:VN:::::::::::
HQ1301A         ::::D:::::T::Q:::E:::::::::::::I:A::::::::::::II::T:::::::::
rrnAC2369       :::IH::::A:::ES::E::::::::::::::SAT::Q::::D::NVI::::E:::::::
VNG2598         ::::D:::::A:::S:::::::L:::::::::S:T::N::::::::V:::T:::::::::
Hut2109         ::::AE:::AP:::D:::::::M::::::::::A:::G::::::::V:::A:E:::::::
Hmu0108         :::::D:::AA::VD::D::::M:::::::::::T:PQ::::DE::::::T:E:::::::
HVO_0436        ::::E::::AD::::::E:E::::::::::::::::::::::T::::::AT:::::::::
Hbo1069         ::::::::::::::D:::::::::::::::::S::::::::::::::I::::::::::::

consensus       KDSFEAPLDVAGLDEPFPAVFIRAPVIDEVGEDVEVLAEWDGRPVAVRDGPVVGTSFHPE
#oth            3.....21123.1221.1.......1.131132131..41112...12112..1.1....
NP0464A         ::::::AI::E::::::::::::::L::::DAA::T::AV:D::::::QDN:::::::::
hla0177         ::::::KIPMT::::::H:::::::L::D:::G:::::TV:::::::::::::A:A::::
HQ1301A         I:::::::::D:::::::::::::::::AA:::AT:::Q:EDN::::Q::A::A:A::::
rrnAC2369       R:::::::::T::N:S::::::::::::Y:::::::::T::D::::::::::::::::::
VNG2598         V:::::::::D::AD::::::::::::::::A:AT:::S:::::::I::::::A::::::
Hut2109         ::::::::::D:::D::H:::::::::E:::-:AD:::T:E::::::::::::::A::::
Hmu0108         ::::::::::::::::::::::::::::A:::G:A::::::::::::KQ:::::::::::
HVO_0436        V:::::::::::::S::::::::::L::::::G:::::::::N:::::::::::::::::
Hbo1069         V::::::::I::M:D::::::::::L::D:DDG:::::::::T:::::Q:::::::::::

consensus       LTADSRIHDLAFFDEVEA---------
#oth            ..4.3.1.2....45444442422111
NP0464A         ::D:::::G::::S----:::::::::
hla0177         ::D::::::::::P:Q:VVA:::::::
HQ1301A         ::P::::::::::ANQNNNVDTAVSTD
rrnAC2369       ::E:P:::::::::S::S:::::::::
VNG2598         ::::V:L:E:::::RTPSAQAGDA:::
Hut2109         ::G:H::::::::E----:::::::::
Hmu0108         ::E:::L::::::ES::::::::::::
HVO_0436        ::P:::L::::::::LAVEIDA:::::
Hbo1069         ::::::L:::::::H:::EAAD:::::