[J] (Tgt) COG0343 Queuine/archaeosine tRNA-ribosyltransferase 8 genomes BUD0833 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1959 rrnAC3258 HVO_2001 Hbo1874 Hmu2439 Hut2899 hla1106 NP2508A -

Pairwise sequence scores
Consensus score	3761	NP2508A	Hut2899	VNG1959	rrnAC3258	Hmu2439	hla1106	HVO_2001	Hbo1874
3000	NP2508A	4004	2544	2536	2580	2523	2500	2644	2705
2850	Hut2899	2544	3754	2447	2581	2487	2508	2521	2540
2968	VNG1959	2536	2447	3779	2634	2545	2540	2600	2586
2970	rrnAC3258	2580	2581	2634	3758	2791	2522	2533	2607
2988	Hmu2439	2523	2487	2545	2791	3775	2522	2666	2609
2992	hla1106	2500	2508	2540	2522	2522	3819	2764	2664
3072	HVO_2001	2644	2521	2600	2533	2666	2764	3928	3079
3086	Hbo1874	2705	2540	2586	2607	2609	2664	3079	3830

529 symbols
consensus       MRDHFEVRDGDAAGRIGELTVPRAGVTVETPALLPVVNPNIQTIEPARLASEFGAEILIT
#oth            1113..3233.321.1.1.3....11.....111..1..136.13.321231...12...
NP2508A         :::I::R::::::::::::S:::::T:::::::::::::H:R::A::E:E:T:::Q::::
Hut2899         ::::::LQAY::M::L::::::::D:::::::::::I::HHE::D:G:::-:::::::::
VNG1959         :::V:::GAQ:GLA:::::D:::::::::::T:M::::::LI:V::S:FVD:::::L:::
rrnAC3258       -MTN::::QY:::::L:::::::::::::::TI::::::HV::VA::T::::::::::::
Hmu2439         :::::::GRY:::::L:::::::::::::::::::::::HV:::::ST::::::::::::
hla1106         ::::::I::H:::::::R:E::::::::::::::::::::VL::::R:::E:::::M:::
HVO_2001        ::::::L::::L:::::R:S:::::::::::::::::::::D::S::::E::::::::::
Hbo1874         ::::::I::::V::::::::::::::::::::::::I::::V:VS::::E:::::Q::::

consensus       NSYIIHGSDDLRERALDQGLHDLLDFDGAIMTDSGSFQLAEYGEIDVTTEEILEFQRDIG
#oth            .1.11443.331121133...1211.2............1...1.212121.13..22..
NP2508A         :G::LY:::EY:::::AD:::::F::S::::::::::::S:::::S::N::::R::::::
Hut2899         :::V:Y:::EV::P::ED:::::::::::::::::::::::::::::N:T:::::::E::
VNG1959         :::::NSD:::::::::E:::EM:G:::::::::::::::::::::TD::A::R::H:::
rrnAC3258       ::::L::::::::PV:E:::::::G::::::::::::::::::D::::::::::::HE::
Hmu2439         ::::L:Q::::::P:ER::::E::::P::::::::::::::::::::::::::A:::E::
hla1106         :::::RST:RI:D:V:::::::F:G::::::::::::::::::D::::::::I::::Q::
HVO_2001        :::::KTN:H:::E:::V:::EM:::::::::::::::::::::::T::::::Q::::::
Hbo1874         ::::::KN:::H:E:::V:::EM::::::::::::::::::::D:T:::R:::Q::Y:::

consensus       SDIGTPVDIPTPPDVDREQAEAELETTQQRLEDAETVDTGEMLVNAPVQGSTYPDLREEA
#oth            1.11....1....113..12331122.321.25.23212.1..22..1..2.2.....2.
NP2508A         :::::::::::::EAS:::TA:D::::KA:::A:::::::::::::::::G:::::::::
Hut2899         :::A::::::::::A::::VGR:M::::A:::T:ADF:A::::L::::::A:::::::Q:
VNG1959         ::::::::::::::A:::::A:::::::::::L:::::V:D:::::::::A:Q:::::Q:
rrnAC3258       ::::::::::::::::::R:TE::K:::E:::H:A:::::::::S:::::A:::::::R:
Hmu2439         :::::::::::::::A::R::S::A:::E:::I:DG:::::::TT::I::::::::::R:
hla1106         ::VA::::V:::::::::R::R:::::K:A:A:::AAE::D:::::::::::F:::::::
HVO_2001        T::A:::::::::::A::::::D::I:R:A:A:::AA:::::::::::::::::::::::
Hbo1874         T::::::::::::::P:::::R::AV:EEA:Q:::D::::::::::::::::::::::::

consensus       ARHAYATDLDVFPVGAVVPLMNSYRYDDMVDAVAAAKRGLGEDAPVHLFGAGHPMMFALA
#oth            122.43.3..1..2..1..11.4...2123111211....1411.1..........1.1.
NP2508A         :E:::G:T::::::::::::::::::G::IE:ILG::::::A::::::::::::::::::
Hut2899         ::D::::G:::::I::::::L:D:::GE::::::G:::::::::::::::::::::::::
VNG1959         GA:::G:A::L:::::::::::Q::::::TE::L:::::::R::::::::::::::::::
rrnAC3258       :AD:VS:G:::::L::::::::E:::A:LA:V:::C::::::VG::::::::::::::M:
Hmu2439         :E::HG::::::::::::::::E:::::LA:V:::C::::::::::::::::::::::M:
hla1106         G:::S:::::::::::M:::L:::::AEV:E::R::::::DP::::::::::::::L:::
HVO_2001        G:::D::::::::::::::M::A::::::::::::::::::V::::::::::::::L:::
Hbo1874         G:A::E:::::::I:::::::::::::::::V::G::::::R:::I::::::::::::::

consensus       VALGCDLFDSAAYALYARDGRYLTVRGTEHLDDLDYFPCSCPVCAEHTPAELRAMD----
#oth            1.2...........11...1.....3..11.111311..4..1.3322.22123431111
NP2508A         ::A::::::::::::::::D:::::A::D:::::E:L::::::::D::::::Q:E:::::
Hut2899         ::A:::::::::::::::::::::::::::::E:EH:::E::::SAR::::::DRP::::
VNG1959         A:::::::::::::I::::D:::::S::::::::H::::D:::::::S:QAV:G:A::::
rrnAC3258       A::::::::::::::::::D:::::Q:::L::E:S::::H::::TD::::::D:::::::
Hmu2439         :::::::::::::::::::::::::::::::::M::::::::::V:YE::D:::::::::
hla1106         ::A::::::::::::M:::::::::S:::::E:ME:::::::::::Y::::::E::GSGG
HVO_2001        :::::::::::::::::::::::::::::::E::::L::T::I:T:YS:DD::EKG::::
Hbo1874         ::M::::::::::::::::::::::::::::E::::L:::::I:TS:S:D::::A:::::

consensus       ---DQERERLLAEHNLHVSFGELRRIKQAIRSGNLLELVERRARAHPAMLDGYRALLDHA
#oth            111454314...1.....113.2111.1..13.2.11..24..12..311..1.2..213
NP2508A         ::::T:::::::R:::::::Q:::T:::::KK::::::::::::G::::V:::::::EA:
Hut2899         :::TH::TK:::::::::::::M::::::::Q::::::::T::::::T::::::::::::
VNG1959         :::AGD::::::::::::::::I::V::::K::T:M:::AA::H:::ST::::::::::S
rrnAC3258       :::ADA::E:::R:::::TY::I:TV:::::::::M:::DS:::G::E:::::::::::S
Hmu2439         :::::RG:D:::R:::::TY::I:T::::::D:D:M:::DS::::::T::::::T:::::
hla1106         DSA::SA:Q:::::::::T:E::::V:A::::::::Q::D::::G:::::::F:V:::::
HVO_2001        :::SKRQ:Q:::::::::T:A::::::::::D:D:M::::E:::S::::::::::::A:V
Hbo1874         :::ET:Q:::::::::::::E::H:V::::::::::::::E:::S::::::::::::E:T

consensus       DQLERTDPVSKDAFFYTSGESARRPEVRRHHDRLDRLDVDGD-VLLTEGD--SNADYDES
#oth            11..23.121.121.12151..3....5..12.13.14342542.112233243432.22
NP2508A         :::::D:::::GS:::L::::::::::K::::::S::S::::R:::S::G::D:SRF::T
Hut2899         E:::::::A:::::::L:::::A:::::::::::A::SPPA:LL:A:DP:AHAG::A:-V
VNG1959         ::::AS::A::::::::GAG:::::::H:::Q::::::::::D:::::::::::HR::::
rrnAC3258       E:::::::::::::::::T:::::::::::Q:::E::P:E:EE::::::S:::S:Q::::
Hmu2439         E:::T::RIA::TV:H::T::::::::V:::Q::::F:LS:S:I:::::E::RDEE::::
hla1106         :E::::::::::::::::H::::::::S::::::S::A:PDR:L::::S:AP::H:::AV
HVO_2001        :::::E::A::G::::A:N:::H::::A:::A:M:::TAE:H:::::::GVP:GD:F:AT
Hbo1874         :::::E:::::GS:::L:E:::F:::::::::::A:::AT:T:::::Q:GTPKGDQF:AT

consensus       WRVLPPFGPFPRALSDTYPLTAEVPERLDRAAYEAAAEGVARLAEENPDTAFTLAHDDWP
#oth            .415.....2.231232..1...2.2.31331123..4..41.126211233212222.1
NP2508A         ::LQ:::::::P::::S::::::L:::::DR::::::K::R::VDDH:E:E:AV::WG::
Hut2899         :A:E:::::V::G:DQ:::::::L:D:::DR::R:::R::N::::TS-:A:I::VD:G::
VNG1959         :N:::::::Y:S::AT:::::::T:A:M:::G::::::::C::::A::::::::::::::
rrnAC3258       :G:::::::Y::E:A::::::::T:D:T:::::::::T::R::V:LH::VS:::V:::::
Hmu2439         :Q:T:::::Y::EM::A::F::::::::SPQ:::T::D:::::::C:::ATV:::QFE::
hla1106         :::K:::::::::::E:::::::::::I:G::QV:::::::S:::S::::EL::G::::V
HVO_2001        :::V::::::::S::E::::::::::::::D:::Q::R::S::V:::::A::::::::::
Hbo1874         :::V:::::::::::E:::::::::D:T::::::M:::::::::A:::E:::V::::G::

consensus       ESALDRVPDGVELENLGADS-----------------------------
#oth            33.1231123.43453445443323233222211122222222211111
NP2508A         DA:::SL::::::LR:::::DHPERDSAQSDMDGDEPKEDYPPGEDENA
Hut2899         A::::LLAE::DIDTTVEE-:::::::::::::::::::::::::::::
VNG1959         ::::EA::QR:S:Y:AVRGE:::::::::::::::::::::::::::::
rrnAC3258       AT::::::E::R:RD:H:RD:::::::::::::::::::::::::::::
Hmu2439         ::::A::::S:TVRH::E:-:::::::::::::::::::::::::::::
hla1106         PR:V:A:::R::T:::RHLGR::::::::::::::::::::::::::::
HVO_2001        ::::A:::ES::::S:S:V:ERLGDEASVGGDDGDDGGSASSAE:::::
Hbo1874         ::::E::::D:TT:SIHSV:PENGEETV:::::::::::::::::::::