[O] (DnaK) COG0443 Molecular chaperone 9 genomes BUD0156 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0491 rrnAC3339 HVO_1590 Hbo3251 Hmu1016 Hut0998 hla2619 NP0218A HQ2640A

Pairwise sequence scores
Consensus score	4688	VNG0491	NP0218A	Hut0998	rrnAC3339	Hmu1016	hla2619	HQ2640A	HVO_1590	Hbo3251
3961	VNG0491	4644	3756	3723	3685	3711	3854	3707	3652	3848
4227	NP0218A	3756	4857	4036	4017	4059	4049	3901	3796	4073
4264	Hut0998	3723	4036	4748	4023	4100	3959	3972	3821	4019
4199	rrnAC3339	3685	4017	4023	4686	4220	3950	3846	3802	3956
4159	Hmu1016	3711	4059	4100	4220	4694	3910	3876	3782	3943
4210	hla2619	3854	4049	3959	3950	3910	4742	3980	3866	4043
4203	HQ2640A	3707	3901	3972	3846	3876	3980	4723	3848	4112
4082	HVO_1590	3652	3796	3821	3802	3782	3866	3848	4620	4076
4354	Hbo3251	3848	4073	4019	3956	3943	4043	4112	4076	4706

657 symbols
consensus       MASNKILGIDLGTTNSAFAVMEGGDPEIIVNAEGDRTTPSVVAFTDDGERLVGKPAKNQA
#oth            ...1....1..............21....2.3..1.....1..22..2.2.........1
VNG0491         :::E::::V::::::::::::::S:::::T:E::::::::I::H-::::L::::::::::
NP0218A         :::::::::::::::::::::::::::::::S::E:::::::::::::::::::::::::
Hut0998         :::::::::::::::::::::::::::::::S::::::::::::-::::Q::::::::::
rrnAC3339       :::::::::::::::::::::::::::::::G::E:::::::::-:::::::::::::::
Hmu1016         :::::::::::::::::::::::::::::::S::E:::::::::-:::::::::::::::
hla2619         :::::::::::::::::::::::DE::::A::::::::::::::A:::::::::::::::
HQ2640A         :::::::::::::::::::::::D:::::::::::::::::::M:::E:::::::::::V
HVO_1590        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo3251         :::::::::::::::::::::::::::::::::::::::::::::::D::::::::::::

consensus       VQNPDETIQSIKRHMGEDDYTVELDGEEYTPEQVSAMILQKIKRDAEEYLGDEIEKAVIT
#oth            11..14..2.......111.1.322111....11..11.....1...1...1121.....
VNG0491         :::::Q::A::::::::E::::A:GDD:::::EI::R::::::::::::::QDV::::::
NP0218A         ::::ED:::::::::::::::::VGDD::::::I::::::::::::::::::D:::::::
Hut0998         :K:::::::::::::::E::::S:::::::::::::::::::::::::::::::::::::
rrnAC3339       :K::::::::::::::::::S::::::::::::::::::::::H::::::::::::::::
Hmu1016         :K::::::::::::::D:::S::::::D::::::::::::::::::::::::::::::::
hla2619         :::::R::::::::::::G::::IGD::::::::::::::::::::::::::DV::::::
HQ2640A         I::::Q::R::::::::E::::::G::D::::::::::::::::::::::::::::::::
HVO_1590        I:::ER::R:::::::::G:::DIE::::::::I:::::::::::::D:::::LQ:::::
Hbo3251         I::::H::R::::::::E:::::I:D:::::::I:::T:::::::::D:::::V::::::

consensus       VPAYFNDRQRQATKDAGEIAGFEVERIVNEPTAASMAYGLDDESDQTVLVYDLGGGTFDV
#oth            .......1.............11.1..1......1......1111..1............
VNG0491         ::::::::::::::::::::::D::::::::::::::::::EDR::::::::::::::::
NP0218A         ::::::::::::::::::::::::::::::::::A:::::::::::::::::::::::::
Hut0998         ::::::::::::::::::::::::D:::::::::::::::::::::::::::::::::::
rrnAC3339       ::::::::::::::::::::::::::::::::::A:::::::::::::::::::::::::
Hmu1016         ::::::::::::::::::::::::::::::::::A:::::::D:::::::::::::::::
hla2619         :::::::K::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ2640A         ::::::::::::::::::::::::D:::::::::::::::::::N::I::::::::::::
HVO_1590        :::::::K:::::::::::::LD:::::::::::::::::::::N:::::::::::::::
Hbo3251         :::::::::::::::::::::::::::I::::::::::::::D:::::::::::::::::

consensus       SILDLGGGVYEVVATNGDNDLGGDDWDEAIIDWLADEFENEHGIDLREDRQALQRLKDAA
#oth            .1..........1..............4.2.12..44.232......1........21..
VNG0491         ::::::::::::A::::::::::::::H::::H:::N:::::::::::::::::::TE::
NP0218A         ::::::::::::::::::::::::::::::::Y:::S::E::::::::::::::::HE::
Hut0998         :::::::::::::::::::::::::::R:::::::ED:AE::::::::::::::::::::
rrnAC3339       :::::::::::::::::::::::::::H::::Y::::::A:::::::D::::::::TE::
Hmu1016         :::::::::::::::::::::::::::H::::Y:::Q::D:::::::D::::::::TE::
hla2619         :V:::::::::::::::::::::::::::L::H::K::K:N:::::::::::::::::::
HQ2640A         :V:::::::::::::::::::::::::D:V:::::G:::DN::::::D::::::::::::
HVO_1590        :V:::::::::::::::::::::::::::::E:::T::::D:::::::::::::::::::
Hbo3251         :V:::::::::::::::::::::::::Q:::::::E::::N:::::::::::::::::::

consensus       EEAKIELSSRKETTINLPFITATDSGPVHLEEDITRAKFESLTEDLIERTVGPTEQALED
#oth            ....1....1...31....112..2..12..3311..1..11.2..11...2......3.
VNG0491         ::::::::::::::V::::V:::::::::::Q:::::T:::I::::::::::::::::::
NP0218A         :::::::::::::N::::::A:::E::LN:::S:S::::::::S::V:::::::::::D:
Hut0998         ::::V::::::::E:::::::S::D::::::T:::::::::::S:::::::E::::::::
rrnAC3339       :::::::::::::R::::::AT::D::LD::QK:::::::::::::::::::::::::A:
Hmu1016         :::::::::::::RV:::::AT::D::LD:::K::::T::::::::::::::::::::A:
hla2619         :::::::::K::::V::::::::::::::::QS::::T::N::S:::::::N::::::S:
HQ2640A         ::::::::::::::::::::::::::::::::TLS:::::::::::::::::::::::::
HVO_1590        :::::::::::::::::::::::::::::::Y:L:::::::::A:::D:::E::::::::
Hbo3251         ::::::::::::::::::::::::::::::::KL:::::::::S:::D::::::::::::

consensus       AGYSKSDIDEVILVGGSTRMPQVQEKVEELTGQEPKKNVNPDEAVALGAAIQGGVLSGDV
#oth            .11222...1.1.........1.221..212.3....1.......1....1.1...2.1.
VNG0491         ::L::::::D::::::::::::::AQ::D:V:::::::::::::::::::V:::::::E:
NP0218A         :::::G:::::::::::::::M:::::::::::::::::::::::G::::::::::::::
Hut0998         :D:::::::::L::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC3339       :D:T::::::::::::::::::::DQ:::M::::::::::::::::::::::A:::::::
Hmu1016         :D:DE:::::::::::::::::::D::::M::::::::::::::::::::::::::A:::
hla2619         :D:::::::::::::::::::::::Q::A:V:::::::::::::::::::V:::::::::
HQ2640A         :::DD::::::::::::::::::R::::D:L:T:::::::::::::::::::::::A:::
HVO_1590        :::D:G:::D:::::::::::::RD:::::L:S::::S::::::::::::::::::G:E:
Hbo3251         :::T:E:::D:::::::::::::H:::::ML:I:::::::::::::::::::::::G:E:

consensus       DDIVLLDVTPLSLGIEVKGGLFERLIEKNTTIPTEESKIFTTAADNQTSVQIRVFQGERE
#oth            .....1........1...........1...1...11..1....11...2.11........
VNG0491         :::::V::::::::::::::::::::::::A:::TA::V:::::::::::::::::::::
NP0218A         ::::::::::::::::::::::::::D::::::::A::V:::::::::::N:::::::::
Hut0998         ::::::::::::::V:::::::::::::::::::::::::::::A:::::::::::::::
rrnAC3339       ::::::::::::::V:::::::::::D::::::::::::::::Q::::Q:::::::::::
Hmu1016         ::::::::::::::V:::::::::::::::::::::::::::::A:::Q:::::::::::
hla2619         ::::::::::::::::::::::::::::::::::::::V:::::::::::NV::::::::
HQ2640A         ::::::::::::::::::::::::::D:::::::::::V:::::A:::::NV::::::::
HVO_1590        ::::::::::::::::::::::::::::::::::::::::::::::::T::V::::::::
Hbo3251         :::::::::::::::::::::::::::::::::::::::::::::::::::V::::::::

consensus       IAEENELLGAFQLTGIPPAPAGTPQIEVTFNIDENGIVNVEAEDQGSGNAESITIEGGAG
#oth            1.21.....2.4.3..............2.2..11.....1...1....2.2......1.
VNG0491         ::S::::::D:H::::::::::::::::::E::AD:::::::::::::::::::::::::
NP0218A         :::::::::::::::::::::::::::::::::::::::::::::::::K:D::::::V:
Hut0998         :::::::::::M:Q::::::::::::::::S:::::::::S::::::::S:E::::::V:
rrnAC3339       :::::::::::A:S::::::::::::::S:::::::::::::::K::::K:D::::::::
Hmu1016         ::N::::::E:A::::::::::::::::S:::::::::::S:::K::::K:D::::::::
hla2619         :::::::::::::S::::::::::::::S:::::::::::::::::::::::::::::V:
HQ2640A         :::::::::E:::A::::::::::::::::::::::::::::::::::::::::::::::
HVO_1590        M::D:::::E:T:S::::::::::::::G:::::::::::S:::K:::::::::::::::
Hbo3251         :::::::::E::::::::::::::::::::::::::::::::::K:::::::::::::::

consensus       LSDEEIEEMQEEAEQHAEEDEQRRERIEARNEAESAVQRAETLLEENEEEVDDD-LRADI
#oth            ...11.12..11..3.1...24..221....1..3221...2.11...152.111.4211
VNG0491         ::::Q:D::::D::A:::::::::R:::::::::T:I::::S:::::::L::E:::E::V
NP0218A         ::::::::::::::K::::::K:::::::::::::TL:::::::D:::DA::::::::::
Hut0998         ::::::::::::::E:::::Q:::::::::::::::I:::::::::::DA:::::::E::
rrnAC3339       :::DQ:::::Q:::::::::::::::::::::::AS:R::::::D:::::I:E:::QS::
Hmu1016         ::::Q:::::Q:::E::::::E::KT:::::::::::::::K:ID:::D:::::::V:::
hla2619         ::::::DQ::::::K:K::::A::::::::::::TSI:::::::::::::L:::E:V:::
HQ2640A         :::::::Q::::::A::::::R:::::::::S:::::::::::::::::DI:::::KES:
HVO_1590        ::::::DR::Q:::::::::KE::RAV:::::::G::::::::::::::N:::E::::::
Hbo3251         :::::::Q:::::::::::::::::::::::::::::::::::::::::Q::::::::::

consensus       EAAIEDVEAVLEDEDATKEELEDATEALSEELQEIGKQMYQQQAAAA--AAGAGA----A
#oth            1232131211111111331221511.3.234......11.24123221211221211222
VNG0491         ND::D::Q:::DEDEPEIDA::T:::E::DT:::::::A::::QD:Q:::GA::-::::-
NP0218A         ::SMD:LRE:V:::::DTD::TE:::::A:A:::::::::::::GEGGAG:::::AGGMG
Hut0998         :SE::A:QET:D:D:::::DY:Q:V:::T:S:::::::::D:AG:EG:::::::::::::
rrnAC3339       ::K:::::E::::::::::DY:AV::T::::::::::::::D::QQ::::G::--:::::
Hmu1016         ::E::N::::::::::DR:DY:A:::::T:Q::::::::::E:::EG:::::::-::::G
hla2619         ::::::::E:::::::DTD:I:S:::::T:::::::::::EG:::Q:GPGGAG:::::::
HQ2640A         :DEV:S::::::::::::::I::V::S::S::::::::::DA:Q:::::G:::::AGAG:
HVO_1590        :::V:::::::::D::STD::::V::E::K:::::::R::::::Q:Q:::G:P:G:::::
Hbo3251         :::MD::::T:::::::::::::::::::K::::::::::::::Q:Q::G:Q:::::::G

consensus       GAGP-----GGMGGMGGAG--GPGGAAGGAG-----DDEEYVDADFEDV-DEDDEDE
#oth            21.111111112.21.1121324223333442232322211....111121122323
VNG0491         --:A:::::::::::::MA:D::::::DAD::::::::::::::::::::::E----
NP0218A         ::::GGMGGA:P:::::::PG:M:::GP:::AGQQG:G::F::::::::D:::::::
Hut0998         :::A:::::::::::::::PA:A::P:::P:GAGDEAG:::::::::E:Q:::::::
rrnAC3339       ::::G:::::AA:-P:::A:::::::::::A::::EQG::::::::::::E:S::::
Hmu1016         A::A:::::::::::::::PG:AAD:G:A:::::::QG::::::::::::::::::-
hla2619         ::::::::::::::::::A:::::::G:AGPGGADA:::::::::::::::DE:DA-
HQ2640A         :::::::::::::D::DM:::DM:::::SGD:::::A:N::::::::::::D:TK::
HVO_1590        :::A::::::AA::P:::-::----------::::::P:DF::::-A:F:::::::N
Hbo3251         :::::::::::A:::::M::::Q::QSP:--:::::::D:::::::::::::::::A