[O] (DnaJ) COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain 9 genomes BUD0458 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0489 rrnAC3334 HVO_1589 Hbo3252 Hmu1012 Hut0979 hla2620 NP0346A HQ2641A

Pairwise sequence scores
Consensus score	2992	HVO_1589	Hbo3252	HQ2641A	hla2620	VNG0489	NP0346A	Hut0979	Hmu1012	rrnAC3334
2203	HVO_1589	3010	2086	1892	1877	1847	1932	1901	1988	1890
2496	Hbo3252	2086	3017	2405	2101	2084	2080	2180	2107	2166
2388	HQ2641A	1892	2405	3011	1965	2036	2075	2049	2065	2063
2300	hla2620	1877	2101	1965	2977	2027	2065	2111	2035	2114
2361	VNG0489	1847	2084	2036	2027	3037	2097	2117	2174	2086
2378	NP0346A	1932	2080	2075	2065	2097	2957	2165	2143	2148
2482	Hut0979	1901	2180	2049	2111	2117	2165	3016	2218	2324
2477	Hmu1012	1988	2107	2065	2035	2174	2143	2218	3008	2257
2508	rrnAC3334	1890	2166	2063	2114	2086	2148	2324	2257	2992

398 symbols
consensus       MSEDFYDVLGVSRDASEDEIKQAYRKKAAEYHPDVSDDPDAEEKFKKIKKAKEVLTDEEK
#oth            ..21..21.....1.2211.24...211321......111...1..221...1..1.211
HVO_1589        ::::::::::::::::K::::N:::::::K:::::::ED::::::::VQ::::::::D::
Hbo3252         :::::::::::::::::::::::::::::Q:::::::E:::::::::V::::::::::Q:
HQ2641A         :::::::::::::N:DG:D::::::::::K:::::::::N:::::::::::::::::G::
hla2620         ::DN:::::::::::::E:::K::::Q:::H:::::::D::::R::A:Q:::::::::Q:
VNG0489         :::::::::::::::T::::M::::DQVS:::::::::::::::::::Q:::D::::::T
NP0346A         ::::::S::::::::D::::::::::::S::::::::::N::::::QV:::::::L:D::
Hut0979         :::::::::::::::::E::QE:::E::R::::::::::::::::::A::::::::::::
Hmu1012         ::::::E::::::::::::::D::::::Q::::::::::N::::::::Q:::::::::::
rrnAC3334       ::Q:::EI::::::::::::QE:::E::R:::::::::::::::::QA::::::::::::

consensus       RQMYDQLGHERFEQAEKRGGT---GGGGGAGG--GGGDPFGGAG-----GGGGGMEDIFD
#oth            .12..12..1..2112.1.152335.3.142.43332311..32121111233323...3
HVO_1589        ::::::V:::::Q:SQ::::GGGGR:Q:NPF::::::N::::M:::::::::::F::::N
Hbo3252         :RQ::::::D::::::::::V:::::A::M::::-R:N::::::G:::::Q:NPF::::S
HQ2641A         :::::::::D::Q:::::::V:::::::NSS:GSAR::::::M:::::::Q:SPFG:::E
hla2620         ::Q::::::D::TE:D:::A-:::T::::P::::-A:G::::::GA:::::A::F::::N
VNG0489         ::Q::::::::::E:::::A:G::N:::::::MG:A:G::::GMGG::::A::::G:::E
NP0346A         :R::::M:::::QE:::::A:DTDR:R::M::::-----M::--:::::::M:::N:::E
Hut0979         ::A::RM::D::::::::::FDDRS:R:::::RRA:::::::--:::::::F:SV:::::
Hmu1012         ::::::V::::::::::H::-:::V:::::::A:::SG::::::GGGPF::::::G::::
rrnAC3334       ::::::M:::::::::::::A::::::::R::::M:::::::G-:::::A::FD:Q::::

consensus       QFFGG-GG-GGRG--RNRPRQGQDLRTRLSIDLEEAYEGVEKQLTVRRPETCPDCDGAGH
#oth            11.11221512221132112..2113132422.21115.12122222.117.32.2.4.1
HVO_1589        NL:N-:::A::QQ::::::Q::R:VAQ:I:::::D::H:::RDV:I::R:V::E:::E::
Hbo3252         :::::G::M::Q:QQ::::::::N::::V:L::::::::::::FS:E:::R::E:::D::
HQ2641A         :::::GQ:QRRQ:::-:::::::N:Q::VQL::::V:T:::::F::::::K::::N:R::
hla2620         :::::G::R::G:::G:::::::::::G:T::::::F::AT:EV:LT::TQ:DT::::::
VNG0489         :::::A::G:::::::SG:E::R::::D:TVT:S:::R::S::V::::::S:A::G:S:Y
NP0346A         :::::::::RSQS:::SG::::S::K:::KV:::D::H::T:::::T:::E:::::::::
Hut0979         ::::::::::::::::D::::::::K:::::G:D:::::::::F::T:::::S::G:E::
Hmu1012         ::::-:--::::S::SSG:Q:::::K:SVT:::::::D::::E:::::::::S::N:R::
rrnAC3334       ::::::::R::::::GS:R::::::Q:::E:::::::N:AT:::N:T:::A:D:::::::

consensus       PPDADVRTCPQCNGQGQQTTVQQTPLGRVQQTQTCRRCDGEGELYSETCSTCRGDGVVRN
#oth            .311113..12.2.2.1212.13.12.....131.22.3.3.231312.13.2.3.3113
HVO_1589        :E::::N::SE:::S::::::::::F::::::T:::A:G::::T:::D::E:::S:R::R
Hbo3252         :A::E:H::::::::::T:::RD:::::::::::::Q:N:::QT:::R::Q:N::::::E
HQ2641A         :S:::::::::::::::T:::RE:A::::::::::P::::S::M:TQ:::::N::::T:Q
hla2620         ::::::E::S::::R::VQQ::::::::::::S::P::E:S::::::D:AD:G::::::E
VNG0489         :E::::::::::D:::VV:Q:R:::::::::R:E:S::G:::::H:::::::G:Q:QT:E
NP0346A         :::::S:::SA:D:R::::::R::A:::::::RE:PQ:::K:TI::::::::::::Q:::
Hut0979         :::::S::::E:E:R::V:R::R::M::::::T::S::::D:T::E::::::::::::::
Hmu1012         :::S:S:::::::::::::::::::M::::::::::::E:D:T::D::::::::::T:::
rrnAC3334       ::G::SE:::E::::::T:Q:::::M:::::RT:::::::::T::D::::::::N:::Q:

consensus       EATLSVEIPAGIRDGQTLRMEREGAPGENGGPNGDLLIEVSVRDHPDFERDGDDLHYRHA
#oth            42213121.2.122..2..131..1..13.112...11116122123.1...12.33441
HVO_1589        TRDVTIT::::F::::R::YRG::E:::::::::::FV::N::::DE:D::::::R:T:P
Hbo3252         ::::E:T::::::::::::::::::::::::::::::::::I:E:E::::::::::H:L:
HQ2641A         ::::::D::::::::::::::::::::D::::R:::::D::::::::::::::::Y::L:
hla2620         :::::::::::::S::S:::::::::::::::::::::::D:DVGDR::::::::RVNE:
VNG0489         R:::T:D::E:::T::::::DG::::::P:A::::::VD:T:EE::::::::::::H:::
NP0346A         :T::Q::V::::::::::::DG:::::::::RK::::V:IRID::ET::::::::RC::P
Hut0979         ::::::DV::::::::S:::::::::::H:::::::::::EIEE:D:::::::N:::TAP
Hmu1012         Q:::T::V::::Q:::::::NG:::::DR:AR::::::::::::::E:D:::A::::HLP
rrnAC3334       D:S:E::::S::A:::::::::::::::::::::::::::Q::::::::::::S:QHQQ:

consensus       ISFPQAVFGDTVEVPTLDGEVELDVPAGTQSGETFRLRGKGMPRLRRRGNGDLYVQVQVV
#oth            11....11.2121.1.21.43132223.....13.12312.1.1.21..5...2.3.311
HVO_1589        :::::::::A::::::::::E::K::::::::S::TVS:A:::H:DG::::::H:E:H::
Hbo3252         :::::::::A::::::VN:TT::EI:K::::::S::I:NE:::H::G::::::H::::::
HQ2641A         :::::::::S::::::VN::TT::IS:::::::E::I:NE:I:H::G::T::::::::I:
hla2620         V::::::::::I::E:V::S::M:::T::::::::::K:::::::::::R:::::K:G::
VNG0489         V::::::::AEI:::::::AATF:LD:::::::::::K:::::::::::::::::T::::
NP0346A         :::::::::::::::::::A::M::::::::::::::::::::::K:::H:::::::R::
Hut0979         :T::::AL::::::::F::P::V:I::::::::::::E:::::::::::Q:::L:T:::Y
Hmu1012         :::::::::::A::E:F::T::F:::S::::::V:::S:::::::::::E:::::E::::
rrnAC3334       :::::::::::IT:::::::::V:::S::::::V:::E:::::::::::H::::::::::

consensus       TPESLNDEQREALEAFAEAGGEEVDVEEGFFEKLKNSL
#oth            1.13.241.11..12....1..223.53.1.311.1.1
HVO_1589        :::D::S::::::KE::::::::--:K::L:Q::::::
Hbo3252         :::N::::::::::::::::::::N:N::::::I::::
HQ2641A         :::N:SQK::::::::::::::S:::SQ:::::I:S:F
hla2620         I:D:::E:::::::::::::::D:::GG:::K:::S:F
VNG0489         :::::S::::D:::Q::::::::I:::Q:::::::::F
NP0346A         ::::::E::::::::::::::::I:::Q:::::::S:F
Hut0979         :::::::::::::::::::S:::I:::K:::DR:::::
Hmu1012         ::DE:T::::D::KQ:::::::::S:D:::::::::::
rrnAC3334       ::D:::A::K::::Q:::::::::::D:::::::::::