[QR] (SmtA) COG0500 SAM-dependent methyltransferases 9 genomes BUD0179 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2147 rrnAC3151 HVO_0309 Hbo1172 Hmu2599 Hut2130 hla0159 NP5034A HQ3251A

Pairwise sequence scores
Consensus score	1629	hla0159	Hut2130	VNG2147	HQ3251A	HVO_0309	Hbo1172	rrnAC3151	Hmu2599	NP5034A
1292	hla0159	1628	1071	1148	1109	1179	1167	1160	1142	1161
1241	Hut2130	1071	1609	1178	1071	1127	1084	1122	1144	1098
1259	VNG2147	1148	1178	1703	1108	1216	1101	1177	1192	1130
1312	HQ3251A	1109	1071	1108	1801	1279	1376	1147	1197	1168
1379	HVO_0309	1179	1127	1216	1279	1615	1364	1199	1223	1207
1349	Hbo1172	1167	1084	1101	1376	1364	1716	1200	1236	1171
1378	rrnAC3151	1160	1122	1177	1147	1199	1200	1616	1321	1276
1393	Hmu2599	1142	1144	1192	1197	1223	1236	1321	1618	1269
1326	NP5034A	1161	1098	1130	1168	1207	1171	1276	1269	1637

238 symbols
consensus       ---------MGVLENKARARLFYKYLSKVYDRVNPFIWNEEMRDEALAMLDIDPDDRVLD
#oth            111111111..1..1.21..1......11..21.211.211..21.15412243312...
hla0159         :::::::::::I::::SN:::::::::::::Q::R:T:T::::T:::SW:EFGD:PK:::
Hut2130         :::::::::::I::D:S::::::::::R::::::::::::R::T:::DL::::A::::::
VNG2147         MRVQANSRS:::::D:::::T:::::::::::::T:::T::::A:::S:::::AE:::::
HQ3251A         :::::::::::I::D:EN::::::::::::::I::::::A:::::::KE:::::T:::::
HVO_0309        :::::::::::::::::::::::::::::::::::::::::::::::E::::QQG:::::
Hbo1172         ::::::::::::::::S::::::::::::::QI::Y::::::::D::EL:G:Q:::::::
rrnAC3151       ::::::::::::::::::::T::::::::::QI:::::D:R:::::I::::LS:::K:::
Hmu2599         ::::::::::::::::S:::T:::::::::::::::::::::::::I:K:::E:::H:::
NP5034A         ::::::::::::::D:::::::::::::A::TI::::::::::::::TWF:::DG:::::

consensus       VGCGTGFATEGLLEHTDDVHGLDQSIHQLEKAFEKFGKHDPVRFHRGDAERLPFADDSFD
#oth            .......1...1.22322121....3..14..34.1.2514.4122........4211..
hla0159         :::::::G:::I:::A:::::::::V::M:::::::::::R:N:Y:::::::::R::T::
Hut2130         :::::::G:::I:::::::Y:::::P::::::TT:L:D-:::Q:CF::::::::::::::
VNG2147         :::::::G:::::K::EH:Y:::::P:::T::W:::::::::A::F::::::::KP::::
HQ3251A         :::::::::::::RYSQ:I:::::::::M::::S:::RT:D:K:Y:::::::::::N:::
HVO_0309        :::::::G:::::RY:::::::::::::MQ::W:::::::E:::Y::::::::::E::::
Hbo1172         :::::::::::::RYS::::A:::::::MQ:::G::::N:E:::Y:::::::::::N:::
rrnAC3151       :::::::::::::::V:T:Y:::::P:::S::::::::FGD::Y:L::::::::K:::::
Hmu2599         ::::::::::::::A:EH:Y:::::A::::::YA::::RG::A:::::::::::Q::T::
NP5034A         :::::::::::::::::::W:::::A:::A::YA::::RGT:N:::::::::::D:N:::

consensus       VVWSSGSIEYWPNPVDALRECRRVAKPGGRVLVVGPDYPNSTVFQKLADAIMLFYDEDEA
#oth            22..........1.141.3.3..221..33..1...11.72421122.........131.
hla0159         I:::::::::::::IEG:::L::::::::Q:::::::::HNP:L:RV:::::::::::::
Hut2130         :::::::::::::::S:::::::::R:::Q::::::N::R:SI:::::::::::::AED:
VNG2147         ::::::::::::H::QG:::L:::::::SQ:::::::::A::::R:::::::::::::::
HQ3251A         :I::::::::::::::::C:F:::V:::N::::::::::D:WI::Q:::::::::::T::
HVO_0309        :I:::::::::::::T::E:F:::V:::SK:::::::D:K:G:::::::::::::::E::
Hbo1172         :I::::::::::::::::E:F:::V:::R::::::::::E:GL::RV::::::::::H::
rrnAC3151       A:::::::::::::::::A::::LT::::K::I:::::::::::::M::::::::::E::
Hmu2599         ::::::::::::::::::E::::IT:::::::I::::::SQS::::::::::::::::::
NP5034A         AY::::::::::::::::A:A:::T::::T::::::::::::L:::::::::::::::::

consensus       DRMFEAAGFEDIEHHIQQARPGSPRAITTIARVPEE----------------------
#oth            11..34..13331.32225612214..1.1.111332122122222222111111111
hla0159         ::::::::Y:AY:::::R:S:Q:::::::V:::S::::::::::::::::::::::::
Hut2130         ::::AE:::D:V::VTMGPGYNPEI::::V::::A-::::::::::::::::::::::
VNG2147         ::::RE::Y:E:Q:RVLRKE:N::P::V:V::A:AADD::::::::::::::::::::
HQ3251A         QE:::T:::V:::::V:::Y::T:Q:::::::A:TADDTVDTPSQQQVSDPAAAPTTD
HVO_0309        :::::::::V::::::L:RQ:::::::V::::A:::::::::::::::::::::::::
Hbo1172         Q::::E:::V:::::::::Y::::K:::::::A::RDDADDEAAIEADT:::::::::
rrnAC3151       ::::TK::Y:EF::::::S::::::::::::E:::-::::::::::::::::::::::
Hmu2599         :::::D:::T:F::F:::N:::::K::::::::::-::::::::::::::::::::::
NP5034A         ::::A:::::TF::R:::RA::T::::::::E::D:K:::::::::::::::::::::