[O] (PRE1) COG0638 20S proteasome, alpha and beta subunits 9 genomes BUD0058 12 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0166 rrnAC1174 rrnAC1773 HVO_1091 Hbo0596 Hmu0625 Hmu1462 Hut0320 Hut0458 hla2367 NP3738A HQ1516A

Pairwise sequence scores
Consensus score	1886	VNG0166	Hut0320	rrnAC1773	Hmu0625	Hut0458	NP3738A	Hmu1462	rrnAC1174	hla2367	HQ1516A	HVO_1091	Hbo0596
1404	VNG0166	1892	1159	1226	1241	1283	1293	1225	1314	1274	1264	1294	1310
1373	Hut0320	1159	1842	1293	1311	1215	1311	1222	1262	1231	1207	1272	1225
1433	rrnAC1773	1226	1293	1805	1565	1275	1329	1258	1321	1255	1270	1263	1297
1531	Hmu0625	1241	1311	1565	1836	1355	1372	1310	1402	1323	1337	1325	1373
1559	Hut0458	1283	1215	1275	1355	2024	1506	1440	1507	1424	1364	1400	1345
1586	NP3738A	1293	1311	1329	1372	1506	1907	1500	1590	1458	1425	1446	1407
1534	Hmu1462	1225	1222	1258	1310	1440	1500	1846	1521	1368	1321	1363	1338
1634	rrnAC1174	1314	1262	1321	1402	1507	1590	1521	1944	1464	1392	1430	1417
1501	hla2367	1274	1231	1255	1323	1424	1458	1368	1464	1991	1445	1411	1409
1525	HQ1516A	1264	1207	1270	1337	1364	1425	1321	1392	1445	1860	1536	1622
1552	HVO_1091	1294	1272	1263	1325	1400	1446	1363	1430	1411	1536	1884	1657
1548	Hbo0596	1310	1225	1297	1373	1345	1407	1338	1417	1409	1622	1657	1910

272 symbols
consensus       MQGQNQQQAYDRGITIFSPDGRLYQVEYAREAVKRGTASIGVRTPDGVVLAADKRIRSPL
#oth            ...231.......1......................1..1.1.142.1.111.123..1.
VNG0166         :::::::::::::::::::::::::::::::::::::::::::::E::::VV::QT::::
Hut0320         :::NQ:::::::::::::::::::::::::::::::S::V::::DE:::::::RQT::S:
rrnAC1773       :::-:E:::::::::::::::::::::::::::::::::V::::E::::I:::RHA::::
Hmu0625         :::::::::::::::::::::::::::::::::::::::V::::A::::::::RHA::::
Hut0458         ::::::::::::::::::::::::::::::::::::::::::::A::::::V::::::::
NP3738A         ::::S::::::::::::::::::::::::::::::::::::I::E:::::VV::::::::
Hmu1462         :::::::::::::S::::::::::::::::::::::::::::::SG:::::V::::::::
rrnAC1174       ::::::::::::::::::::::::::::::::::::::::::::S::::::V::::::::
hla2367         ::::S::::::::::::::::::::::::::::::::::V:::AE::::::::::A::::
HQ1516A         ::::A::::::::::::::::::::::::::::::::::V:I:::::I:::::::S::::
HVO_1091        ::::A::::::::::::::::::::::::::::::::::::::::E:::::::::S::::
Hbo0596         ::::A::::::::::::::::::::::::::::::::::::::::E:::::::::S::::

consensus       MERDSVEKIHKADDHIGIASAGHVADARQLIDFARRQAQVNRLRYGEPIGVETLTKEVTD
#oth            2.23.1..2.13.1.112..........1.1.21.111.1121..21331112...41..
VNG0166         L:GS::::L::I:::V:A::::::::::::V::::Q:S::E:V::D:::::R::::S:::
Hut0320         I::::I::T::I::::A:::::::::::K:::::::R:::E::::DQ:M:::A:::AI::
rrnAC1773       I::::I::::EI:S:V:V::::::::::::::V::::S:::::::D::AS::S::::I::
Hmu0625         L::::I:::::::::V::::::::::::::::L::::::::H:::::E::::S:::::::
Hut0458         :::::::::::::::::::::::::::::::::S:::::::::::D:A::::::::Q:::
NP3738A         :::T:::::::::::::::::::::::::::::::::::::Q:::D::::::::::A:::
Hmu1462         :::S::::::::::::::::::::::::::::L:::R::I:::::E:R:::::::::I::
rrnAC1174       :::S:::::::::::::::::::::::::::::::::::::Q::::::V::::::::I::
hla2367         ::PE:I::L::::::V:V:::::::::::::::::::::I:::::::A::I:::::NI::
HQ1516A         ::PT:::::::T:::V::::::::::::::::::::::::::::::::V:I:::::N:::
HVO_1091        ::PT:::::::::::::::::::::::::::::::::S::::::::::::I:::::::::
Hbo0596         ::PT:::::::S:::::::::::::::::::::::::S::::::::::::I:::::::::

consensus       HIQQYTQVGGARPFGVALLIGGIEDGEPRLFETDPSGTPYEWKALAIGADRGDIQEYLEE
#oth            31.2...2........1.211.232.2.1.1.......11..2.111.23.4131421.2
VNG0166         ::::::::::::::::::::A:V:G:::::::::::::SN::::V:::SN::::::F::D
Hut0320         T::E:::T::::::::S:IV::M:N:::::::::::::::::S:::V:GG:EE::::F:D
rrnAC1773       Y::::::T:::::::::::VA:::::::::::::::::::::Q:V:::GS:E:::TF:::
Hmu0625         Y::::::T:::::::::::V::::::::::::::::::::::Q:V:::G::DE::TF:::
Hut0458         :V:::::I::::::::::M:A:VS::::S:Y:::::::::::::::::::::::R::::A
NP3738A         ::::::::::::::::::I:::::::::::Y:::::::::::Q:::V:::::::::::::
Hmu1462         :::R::::::::::::::I:A:VA::::::Y:::::::::::::::V::::A:TRA::::
rrnAC1174       Y:::::::::::::::::I::::VN:::::::::::::::::::::V:::::::RD::::
hla2367         :::::::I::::::::::IV::::N:::::::::::::::::Q::S::S::S:LRD::::
HQ1516A         N:::::::::::::::::::::::::S:::Y:::::::::::::VS:::::S:L::H:::
HVO_1091        ::::::::::::::::::::::V:N:T:::Y:::::::::::::VS:::::::H::H:::
Hbo0596         ::::::::::::::::::::::::N:T:::Y:::::::::::::VS:::::::L:GF:::

consensus       NYDEGLDLDEGIGLALRALASVNDDGLDPEGVDVATVDVETEQ-FRELSDDEIEAYLAER
#oth            2152413214124...42133431232434111221143134612852452233432425
VNG0166         E::A::SV:D::D::::::NEGRE:A:SGD::G:GI::AD:GT:Y:::AA::SQS:IDDI
Hut0320         ::ED:MT:EQ:V::::EG::EP:::::::D:::LQ:::E:G--:VLGV:Q:V::EH:E::
rrnAC1773       E:A::M::EG::E::::::::::E::::AT:::I::I:::S::::EK:AE:D:AER:E:F
Hmu0625         E::::M::EA:LS::::::G::S:::::AT::::::I:::S::::TA::E:::AERVT:L
Hut0458         ::::EMT:EA:V::::K::E::AEG::T::::GI::IP::DAE::H::T:A:T::::SDL
NP3738A         H:S:S::TEA::::::E::::::::S:T:::IGL:::T:DDDDG:SQ:::E::::H:E::
Hmu1462         H:S:T:A::GA:::::ET:::::::A:A::A:GL::::A:::::::T:::E:T:TH::::
rrnAC1174       H::::M:::::VD:::A::::::::E:S:::IG:::::::::T::GQ:T:E:K::H:::A
hla2367         E:E:::ST::AVA:::DT::QS::GE:S::::G:::IT:DD:E:YE:RPT::::SI::D:
HQ1516A         ::T:E:S::::V:::::TI:IS:::E:TAA:::::::ASD::E::I::TN:::S::I:DN
HVO_1091        :FRDD:T:::::E:::E:I::TS:E:TA:D:::::::SA:::R::V:::N::::S::EAN
Hbo0596         ::RDD:T:::::::::::I::T:::EIEEG::::::ISA:::A::V::DN:::SD:I::N

consensus       DLLADDEDDDD---------------------
#oth            11345233453333332313222221221111
VNG0166         EDA:::S::::DEE::::::::::::::::::
Hut0320         :::GG:DE---:::::::::::::::::::::
rrnAC1773       E:GGEE-----:::::::::::::::::::::
Hmu0625         E:EG::DE---:::::::::::::::::::::
Hut0458         ::::T::::ATADDDTDTTADEGDTDDDSVDE
NP3738A         :::EAED:A:EDDEE:::::::::::::::::
Hmu1462         :::::G::LEE:::::::::::::::::::::
rrnAC1174       :::DTG::A::EAEDEDATEE:::::::::::
hla2367         ::::S:::EA:DADADGETDDANAGDEE::::
HQ1516A         ::EPAE:T:SE:::::::::::::::::::::
HVO_1091        ::::TED:EQTEE:::::::::::::::::::
Hbo0596         E:EPSE:::ETDEPAE::::::::::::::::