[C] (Tas) COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) 8 genomes BUD0975 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2023 rrnAC2912 HVO_1874 Hbo1753 Hmu2801 - hla0990 NP4488A HQ1093A

Pairwise sequence scores
Consensus score	2716	VNG2023	hla0990	rrnAC2912	Hmu2801	NP4488A	HVO_1874	Hbo1753	HQ1093A
2069	VNG2023	2728	1822	1870	1857	1908	1925	1861	1821
2060	hla0990	1822	2773	1927	1921	1929	1896	1799	1798
2214	rrnAC2912	1870	1927	2724	2230	1982	1954	1976	1913
2194	Hmu2801	1857	1921	2230	2831	1946	1987	1889	1901
2227	NP4488A	1908	1929	1982	1946	2712	1980	2085	2024
2370	HVO_1874	1925	1896	1954	1987	1980	2749	2193	2174
2283	Hbo1753	1861	1799	1976	1889	2085	2193	2774	2345
2294	HQ1093A	1821	1798	1913	1901	2024	2174	2345	2827

382 symbols
consensus       -----MNYRELGNSGVEVSEVGFGAWVVGTDWWGDRTRDDAIEMVHHAIDQGITYFDTGD
#oth            11111.3211..3.12....1........1......23311221232.21311111....
VNG2023         ::::::QH::::D:::::::::::::::::::::::DE:::L:::EY:L:H:::::::::
hla0990         ::::::QH::::::::::::I:::::::::::::::SDEQ:VG::ED:L:A:V::V::::
rrnAC2912       ::::::E:AT::::::::::::::::::::::::::::::::D::Q::L:EDV:F:::::
Hmu2801         :::::::E::::T:::::::I:::::::::::::::S::Q::::::::::::V:::::::
NP4488A         :::::::::T::E::L::::I::::::::S:::::::EQQ::D::RY:V:::::::::::
HVO_1874        ::::::H:::::T::I::::::::::::::::::::SDE:S:::L::::E:::DF:::::
Hbo1753         :::::::::T::::D::::::::::::::::::::::K::S:::I::::EE:::::::::
HQ1093A         MHCFG:H::T::T:::::::::::::::::::::::::S:S::LI:::::::::::::::

consensus       VYGHGDSEEIIGEALAEYRDEVTVATKIGYDFYNNPQAGHGELPKEITGEWLREATEKSL
#oth            .....4..322.3.12331111.11..1.................233311224.322.1
VNG2023         :::::R:::LL::::::HG::M:::::V::::::::::::::::::MGVDY::D:V:::M
hla0990         ::::::::::::R:IGGR:::::L::::::::::::::::::::::LDR:Y:ET:F:R::
rrnAC2912       :::::::::::::::::H::::::S::::::::::::::::::::KV:P::VHT:VDR::
Hmu2801         :::::A:::L:::::::::ED:::S::V:::::::::::::::::R:D:::I:::LDD::
NP4488A         ::::::::QLL:K::EPV::::::::::::::::::::::::::::MHRDY:E::F::::
HVO_1874        :::::H:::VV:::::D::::::::::::::::::::::::::::::::::V::::::::
Hbo1753         :::::E::KV::::I:D::::::L:::V::::::::::::::::::M::::V:S::::::
HQ1093A         ::::::::S:::D:::P::::::::::V:::::::::::::::::::::::I:N::RR::

consensus       DRLDMDYVDLLQLHNANVDEVDADVLEALDELREEGRVDAIGWALGPSIGWLAEGDAAIE
#oth            1..1212.12.1...111.12121.123.111111.222.2.2..........1..4.13
VNG2023         :::GV:H::V:::::PD:::LTP:::DL::D::AD::A::::V:::::::::::::H:::
hla0990         ::::T::::::::::::::DITPE:RDL:R:WKAD:::R:L:::::::::::::::::V:
rrnAC2912       :::G::H:E::M::::::::::E:::::::::::::K:::::::::::::::::::::VA
Hmu2801         E::::E:::M:M:::::A::::::::AT::::::::K:E::::::::::::::D::::VQ
NP4488A         :::G::S:EM:::::::A::I::::::F::::::::::::::M:::::::::::::L:::
HVO_1874        E::::E:::::::::::::::TP:::::::::K:::LIE:T:::::::::::::::V:::
Hbo1753         E::GV:H:EV::::::::::::E:::::::::::::L:::::::::::::::::::M:::
HQ1093A         :::::E:::V:::::::::::::::::T::::::::L:::::::::::::::::::L::T

consensus       -EEFDALQLVWNLFEQDVGNHFLDTIRETGSDTSLIARVPHSSGLLNEQVTPETELGEGD
#oth            121..11.3.2.31..4112..2112223213..121.......1.....1.1.22241.
VNG2023         :AA::SV:Y:G:VL::::H:::V:SV::R:AA::::P:::::::::::::::D:::::::
hla0990         Y:::::V:T:F:::::QP:R::V:::::::::::V:::::::::::::::::D:V:ED::
rrnAC2912       :N::::::T:F:::::TP:Q::I:::::QNA:::VL:::::::::::::::::::::K::
Hmu2801         :N::::::T:F:M:::VP:Q::::::::LDA:::VV::::::::::::::::D:::::::
NP4488A         ::::::V:::::ML::E::::::::LER:::A::::P:::::::::::::::::::D:::
HVO_1874        ::::::::I:::A::::::::::::::::::S::::::::::::::::::R::::::S::
Hbo1753         :::::S::::::M:::E::::::::VER:::P::::P:::::::::::::::::GHDLD:
HQ1093A         :::::SV::::::::::::::::N::KK:N:S::::P:::::::I:::::::::GYDLD:

consensus       HRGFRPDEWYETGWEKVEALRFLER--------------DGERTMGQAAIQWLLSHDEVA
#oth            ..22..41......1.2142....121121111111111113.1.2..1121..43.211
VNG2023         ::::::E::::::::::D:::::::::::::::::::::::::::::::::::::F::::
hla0990         ::SH::Q:::::::K::D:I::::DPDGV::::::::::E:T:::A::::R:::A:::::
rrnAC2912       ::SH::S:::::::::::EI:::::::::::::::::::::A::::::::::::YN::::
Hmu2801         ::SH::T::::::::::DSV:::::ADGASGDEPRGDHA::R:::A:::L::::Y:::::
NP4488A         ::AY::::::::::::I:S::::::::::::::::::::::::E:S:::L::::F::S::
HVO_1874        ::::::::::::::::L:Q::::::::::::::::::::::::::A::S:AY::GY::T:
Hbo1753         :::::::A::::::::L:T:::::::::::::::::::::::::::::::AY:::::A::
HQ1093A         :::::::A::::::::I:T:::::::::::::::::::::D:::::::::AY:::::A:P

consensus       SVTPTFRTKADIDEWAAASDVPKLSDEEYERVQELYADNFGIDRDDGM--DALRSSVDGE
#oth            2.....1252..41.13.121.2.122.331.32..22..11121...11141.1..1.2
VNG2023         T::::::S::::EA::S::ET:A:::A:R:::A::::::::V::F:::EKEDY:T::::D
hla0990         :::::::DGD::A::S::::::P::EA::D::E::::R::D::::::::::V::T:::::
rrnAC2912       ::::::::N:::::::G:P:T:P::::::D::::::R::::::::::::::::::::G:A
Hmu2801         ::::::::A:::::::G:PAT:A:::A::::::::::::::V:::::::::Q:::::G::
NP4488A         T:::::::RD::::::::::::P::::::::::S::::::::EG:::::::::::::G::
HVO_1874        A:::::::::::::::K:::::::T:G:MT::E:::::::::::F::::::::::::::D
Hbo1753         ::::::H::E::T::::::::::::E::MT::SD::E::::::C:::::::E:::::G:D
HQ1093A         T:::::H:SE::SA:::::::::::A::LSK:SS:::E:::::::::::::Q::::::::

consensus       DIRAAGIDKRAA-G--------
#oth            .1231.3434435321131211
VNG2023         :L:D:::LGS:D:-::::::::
hla0990         ::E:::L:::::SY::::::::
rrnAC2912       :LEET:MKSAGD:-::::::::
Hmu2801         :LDET:TAPADD:-::::::::
NP4488A         ::ES::L::ES:GS::::::::
HVO_1874        ::::::L:::V:K:ARNEA:::
Hbo1753         ::D::::::K:SA:PRNSAD::
HQ1093A         :::::::N:::TR:PRNTASSD