[Q] (HutI) COG1228 Imidazolonepropionase and related amidohydrolases 4 genomes BUD1911 4 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1211 rrnAC1790 HVO_A0560 Hbo2707 - - - - -

Pairwise sequence scores
Consensus score	3036	HVO_A0560	VNG1211	rrnAC1790	Hbo2707
2284	HVO_A0560	3060	1847	1904	1838
2336	VNG1211	1847	3117	1974	1806
2478	rrnAC1790	1904	1974	3148	2046
2302	Hbo2707	1838	1806	2046	3012

431 symbols
consensus       MTDLDA-----VVHGAAELVVGPAADGRRLETHEDAAVAIVDGAVAAVGPTAEVLAEYPA
#oth            122122111111122.2.1.21112213212231.1.1.22..311...1.21.112..3
HVO_A0560       V::AGSTAGLT:::D::::::::-DE:TGVVVL::::F:AL::E:V::::::::::D::V
VNG1211         :SS:::::::::::::R::::::::G:DT::::A:G:::V:::::::::D::D:::A:::
rrnAC1790       ::T::::::::::Y::D:::A:::T:::::::Y::G:::::::T:::::::T::T::::P
Hbo2707         :I::--:::::LLTN:::V:TY--::HE::DSI:::::::E::HIV:::::D::TS:::E

consensus       EDAETAIDATGQAVLPGFVDPHTHALFAGDRSDEFAAKLRGKTYQDILAEGGGILRTVDA
#oth            12.2212.1211112....................2...1.12.11..11........2.
HVO_A0560       ::::::::::DKT::::::::::::::::::::::V:::Q:A::E::::D::::::::::
VNG1211         :N:T:::::::KT:::::::::::::::::::::::::::::P::E::::::::::::::
rrnAC1790       :S:NH:V::D::::I:::::::::::::::::::::::::::S:::::::::::::::R:
Hbo2707         S:::NVL:CA:::IV::::::::::::::::::::E:::::::::E::S:::::::::E:

consensus       VRDASDDELVANLLAQLDVMLAHGTTTAEVKSGYGLDTETELRMLRAIDAAAARHPVDVV
#oth            ..211222.231.2211.2........1...1.........11..31.12.223..11.1
HVO_A0560       ::GV:::::AVT:ADH::A::::::::V:::T:::::::::::::SV::::GSD:::::I
VNG1211         ::A:::AA:::::T:::::::::::::::::T:::::::::C:::D::A::::E::::::
rrnAC1790       ::::DEET:LS::::H::T::::::::V::::::::::::::Q:::V::S:D:V::::::
Hbo2707         :::::T::::E:::E:F::::::::::::::::::::::::::::E:::R::D:::IR::

consensus       PTFMGAHAVPRGTDADDYTEAVVDDQLPAVAAQGIAEFCDVFCEEGVFTVEQSRRILDAG
#oth            1..1......312.112.121.111.2.12121.1.1.......21..211....1.1..
HVO_A0560       ::::::::::::A::EE:::S::S::::::::::::::::::::R::::A::::::::::
VNG1211         T::L::::::DD::::A:VD::I::::::-::N:P:R:::::::AD::::::::::::::
rrnAC1790       ::::::::::E:W:T::::A::::E:V:::ES::::::::::::::::S:A::::V:E::
Hbo2707         ::::::::::N:::T:::V:S::SE:I:KA:E::::::::::::::::D::::::V:E::

consensus       REHGLTPKVHAEELAHIGGTQLAADVGAASADHLLHATGEDIDALVDAGVTPVLLPGTAF
#oth            221..1..2..1.1121..111..21..1.......112.1211.11.21......1...
HVO_A0560       :D::::::I::D:F:A::::DV::S:::::::::::TDD:GR:T::::::::::::::::
VNG1211         :::::A::L::::FTRL::A:::::L::T:::::::::P::AA::A::::::::::A:::
rrnAC1790       AAA:::::::::::::::::::::::::::::::::::::::::::::A:::::::::::
Hbo2707         K:::::::::::::T:L:::::::E:::T:::::::T:::::::::A:DT::::::::::

consensus       GLGAAYADARAFLDA-----GAPVALATDLNPNCYSHSMGFAASLACVEMRMTPAEALRA
#oth            1.112...132.12211111.11..11..1....222..2.131.1111.111.12.231
HVO_A0560       ::::D::::::::::::::::HE::::::F::::FAR::S:V:T::S:G:::::H::I:G
VNG1211         V:DE::::PQQ::A:ADNRT::::::G::::::::T:::::VV::::NG:::A::D:VL:
rrnAC1790       :::::::::T::R:R::::::::::V:::F::::H:::::::L:::::::GL::::::I:
Hbo2707         ::::E::::EM::EH:::::::::::::::::::::Q::P::MT:G::::G::::Q::G:

consensus       ATAAAARALDRA-DGTGTLREGAPADAVVLDAPSHVHLPYNFGTNNVDAVLKDGEVARD-
#oth            3.33..3.1..31112.1.11.211.22.111.121.11.2211.31211121.3.1332
HVO_A0560       V:S:::G::::D::::::::T::::::::::V:TAS::S:R:D::P:ST:::S:V:::E:
VNG1211         :::W::S::::GR:::::::::TDG:VL:V:::::::::::P:V:::E:::T::T::VGG
rrnAC1790       G:KH::L::::T:::L::::::::G:::::A::::::I::QY:::V:::I::::S:VSTP
Hbo2707         S:VN::::I::::EA-:R:ET:S:::LA::::::Y:::S::::V:SI:T:VI:::::H::

consensus       -----------
#oth            22211111111
HVO_A0560       :::::::::::
VNG1211         GGA::::::::
rrnAC1790       THESYDREVQP
Hbo2707         :::::::::::