[I] (FadB) COG1250 3-hydroxyacyl-CoA dehydrogenase 8 genomes BUD0985 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0681 rrnAC0771 HVO_1444 Hbo0110 Hmu0952 - hla0823 NP1906A HQ2302A

Pairwise sequence scores
Consensus score	2142	HQ2302A	rrnAC0771	Hmu0952	NP1906A	VNG0681	hla0823	HVO_1444	Hbo0110
1632	HQ2302A	2146	1396	1388	1542	1438	1472	1505	1523
1667	rrnAC0771	1396	2116	1560	1494	1484	1479	1532	1534
1695	Hmu0952	1388	1560	2113	1522	1513	1520	1545	1577
1716	NP1906A	1542	1494	1522	2126	1612	1555	1612	1579
1756	VNG0681	1438	1484	1513	1612	2129	1602	1614	1669
1807	hla0823	1472	1479	1520	1555	1602	2119	1592	1661
1832	HVO_1444	1505	1532	1545	1612	1614	1592	2140	1740
1866	Hbo0110	1523	1534	1577	1579	1669	1661	1740	2149

288 symbols
consensus       --MRDLEDIDTVGVVGAGTMGNGIAQVAATAGYDVVMRDIEQEYVERGLDAIDDSLDRLV
#oth            1234425333211........2.....1.21..3..1..33622.34.133.31113131
HQ2302A         :MT::I:SVERI:::::::::S:::::T:A::::::L:::KTKF::D::V::A:R:::D:
rrnAC0771       ::-MH::KV::::::::::::::::::::::::N:::::MTD:L:AA:FEE:QS:FET::
Hmu0952         :::S:IGE:Q::A::::::::S::::::::H::::::::VAEDL:TE:FE::::::S:::
NP1906A         :::LTTDSL:R::::::::::S:::::::A:::::::::::::::DS:FET:A:::::K:
VNG0681         ::::S:A:TE:I:::::::::A:::::::::::T:::::::::::DA:F:S:ES::::F:
hla0823         ::::E:S::GV::::::::::::::::::::::E:::::::S::::::::S:::::A::D
HVO_1444        :::Y:T:::::::::::::::::::::::M:::::::::L:P:::::::S::::::S:F:
Hbo0110         MDI:E:P:VE:::::::::::::::::::M::::::::::KM:F::::::S:E:::S:F:

consensus       EKDRLTESEADAARDRITGTTDLDDLADADLVVEAAVEDMDVKRDIFADLDEVTDEDVVL
#oth            342432261332152.13...2122.2311111..11.1311.211.3...3435412..
HQ2302A         :AE:RS:::TAMIQ:::::::A::::TTC::I:::::::::I:Q:::S::::M:NN:T::
rrnAC0771       AR:TV::Q::E::TA::::::EM::::::::::::VT::::I:QSV:E:::A:CGP:T::
Hmu0952         AN:T:::::ST:::E::::::::::::::::::::V:::VE:::SV:S:::::CRSG:::
NP1906A         KSGDY::K::E:I::::E:::A:G::::CG::I::::::I:::K:V:::::GLV-D:A::
VNG0681         SN:D:S:AD:::IV:::::::::AE:::C:V:I:::::::EI:Q:::R:::DALP:::::
hla0823         ::G::D:-DPA:I::::E::::::A::A::V:::::::NL:::K:::::::G:::D::::
HVO_1444        S:EK::GD:::::KA:VA:::E:A::G:C:::::::::N::::::::::::DIVP:G:::
Hbo0110         :::Q:SQT:::D:L:::R:::E:A:::V::::::::::::::::::::::::::::::::

consensus       ATNTSTLSITTIASATDRPERVVGLHFMNPVPIMKGVEVVVGEKTADDVVAFAHEFAEDL
#oth            .1....1...1..12.22125.2.2.......2.2...2.2..1.345214212312341
HQ2302A         ::::::::::S:::I:EY:D::I:I:::::::V:D:::L:A::R:::::LS::QS:INI:
rrnAC0771       :S::::::::::::V:E:::Q:L:::::::::V:::::L::::::S:ET:TLGR:::H:I
Hmu0952         ::::::I:::::::::T:::H:::::::::::L:::::L::::R::EAT:EA:::::AS:
NP1906A         ::::::::::::::::TS::::::::::::::V:::::I::::::RPGI:D::::::AE:
VNG0681         ::::::::::::::V:::AS::::::::::::::T::::::::::DA:::::::AL::::
hla0823         ::::::::::::::::::ASD:I:::::::::::D::::::::R:::P::D:::A:::::
HVO_1444        :::::::::::::A::E:::L:::::::::::::::::::R::::D::::::::D:S:A:
Hbo0110         :::::::::::::A::::::N:::V:::::::L::::::::::::DSK::EL::::S:E:

consensus       GKETWESDDKPGFVTNRILMPWINEGIRAYDEGVASKEDIDRGMTLGTNVPMGPLELADH
#oth            1..1.11.......1..1....1...1..1..1..212...3.11....1.....1....
HQ2302A         :::A:V::::::::::::::::::::::::::D::T:::::K:::::::A:::::T::::
rrnAC0771       ::::::A:::::::V::V::::::::V::::::::D:A:::::L::::::::::::::::
Hmu0952         D:::::::::::::::::::::L::::::::::::T:D::::::K:::::::::::::::
NP1906A         ::::::::::::::::::::::L::::::F:::::::::::A::K:::::::::::::::
VNG0681         D:::::::::::::::::::::::::V::F:::::::D:::T::K:::::::::::::::
hla0823         ::::::A:::::::::::::::::::V::::::::DR:::::::::::::::::::::::
HVO_1444        ::::::::::::::::::::::L::::::::::::::::::::::::::::::::T::::
Hbo0110         D::::::::::::::::::::::::::::::::::T:::::::::::::::::::T::::

consensus       IGLDVCLDASETLHEELGDRYKPAYLLKRKVEAGDLGKKTGQGFYDYD
#oth            ....11.1.11..2211....1....12...2..1....1.5...2.1
HQ2302A         ::::I::H:T:::YN:F::::::::::::::::::::::::R::::::
rrnAC0771       :::::V:::::::Y:::::::::::::::::A:::::::S::::::::
Hmu0952         :::::V:::T:::::Q:::::Q:::::R::::::H::::S:N:::E:E
NP1906A         :::::::H:::::Y:::::::::::::::::::::::::::E::::::
VNG0681         :::::::::::::::::::::::::::Q:::D:::::::::A:::T::
hla0823         :::::V::::::::T:::::::::::V::::::::::::::K:::E:E
HVO_1444        ::::I::::::::F:::::::::::::::::A:::::::::K:::E::
Hbo0110         ::::I:::::Q::::::::::::::::::::D::::::::::::::::