[C] (LldD) COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases 2 genomes BUD4038 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG5084 VNG5213 VNG6081 VNG6445 - - - - - - NP0360A -

Pairwise sequence scores
Consensus score	2670	VNG5084	VNG5213	VNG6081	VNG6445	NP0360A
2670	VNG5084	2810	2810	2670	2670	2010
2670	VNG5213	2810	2810	2670	2670	2010
2670	VNG6081	2670	2670	2670	2670	2010
2670	VNG6445	2670	2670	2670	2670	2010
2010	NP0360A	2010	2010	2010	2010	2645

379 symbols
consensus       -------------------MTAQDSTQTEDRKDDHLQIVQERDVETTGTGFDDVHLVHNA
#oth            1111111111111111111.1111111........11.11.1...11...11..1...1.
VNG5084         MGESRYNSIVFPSLVQTRL:::::::::::::::::::::::::::::::::::::::::
VNG5213         MGESRYNSIVFPSLVQTRL:::::::::::::::::::::::::::::::::::::::::
VNG6081         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6445         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP0360A         ::::::::::::::::::::PDSEPSE::::::::VR:IR:E:::SG:::LG::R:::E:

consensus       LPELDYDAIDPSIDFLGHDLSAPIFIESMTGGHHNTTEINRALARAASETGIAMGLGSQR
#oth            ..111..1..1..1...11.1...1........1...1......1..1.......1....
VNG5084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5213         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6081         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6445         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP0360A         ::DVH::D::T::P:::AE:D:::V::::::::A:::D::::::A::A:::::::V::::

consensus       AGLELDDERVLESYTVVRDAAPDAFIYGNLGAAQLREYDIEMVEQAVEMIDADALAVHLN
#oth            ........1.........1......1.........1...1.1..1...............
VNG5084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5213         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6081         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6445         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP0360A         ::::::::G:::::::::E::::::L:::::::::K:::L:T::R:::::::::::::::

consensus       FLQEATQPEGDVDGRNCVAAIERVSEALSVPIIVKETGNGISGETARELTAAGVDALDVA
#oth            .....1.......1.1.11.....111....11.......111....1.11.....1...
VNG5084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5213         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6081         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6445         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP0360A         :::::V:::::::A:G:LP:::::VDG::::VV:::::::FAA::::R:AD:::::I:::

consensus       GKGGTTWSGIEAYRAAAANAPRQKQIGTLFREWGIPTAASTIECVAEHDCVIASGGVRTG
#oth            .........1.......11.1..111.1......1...1..1..1......1........
VNG5084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5213         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6081         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6445         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP0360A         :::::::::V:::::::VG:S::ERV:E::::::V:::V::L::A::::::V::::::::

consensus       LDVAKAIALGARAGGLAKPFLKPATDGPDAVIERVGDLIAELRTAMFVTGSGSIDELQQV
#oth            .....................1..11.11..1..11..11...........11111..11
VNG5084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5213         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6081         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6445         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP0360A         :::::::::::::::::::::E::AS:TE::V::IE::KT:::::::::::PTVAD::ET

consensus       EYVLHGKTREYVEQRTSSE
#oth            1...1.1..1.....1111
VNG5084         :::::::::::::::::::
VNG5213         :::::::::::::::::::
VNG6081         :::::::::::::::::::
VNG6445         :::::::::::::::::::
NP0360A         D:::L:G::Q:::::GD--