[S] (-) COG1469 Uncharacterized conserved protein 9 genomes BUD0604 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1901 rrnAC3309 HVO_2348 Hbo2031 Hmu2283 Hut2979 hla0996 NP2514A HQ3317A

Pairwise sequence scores
Consensus score	2313	VNG1901	hla0996	HQ3317A	HVO_2348	Hbo2031	NP2514A	rrnAC3309	Hut2979	Hmu2283
1820	VNG1901	2330	1680	1623	1689	1716	1692	1633	1614	1675
1973	hla0996	1680	2302	1716	1899	1832	1661	1716	1684	1694
1876	HQ3317A	1623	1716	2307	1881	1887	1614	1666	1600	1656
1988	HVO_2348	1689	1899	1881	2297	2020	1693	1687	1645	1677
1992	Hbo2031	1716	1832	1887	2020	2322	1742	1731	1652	1732
1885	NP2514A	1692	1661	1614	1693	1742	2353	1768	1807	1810
1925	rrnAC3309	1633	1716	1666	1687	1731	1768	2308	1835	1844
1913	Hut2979	1614	1684	1600	1645	1652	1807	1835	2578	1870
1924	Hmu2283	1675	1694	1656	1677	1732	1810	1844	1870	2313

341 symbols
consensus       MSQQLPDVQASSPDVTVGLSRVGVTGVEKLVKIARDDKRPIVLMAEFEVFVDLPSGRKGI
#oth            ..2....1..24.1.2...12....1.1...114.5242.11...1.1.1....31...1
VNG1901         ::::::::::TE:::S::::E::::::::::E:::E:D:::::::::::Y::::R:::::
hla0996         ::H::::::::A:::S::::Q::::::::::::::G::::::::::::::::::::::::
HQ3317A         ::H::::I:::R::::::::Q::::D:D:::::E::GET:L:::::::::::::::::::
HVO_2348        ::H::::::::Q::::::::Q:::::::::::::::G:::L:::::::::::::G:::::
Hbo2031         ::H::::::::R::::::::Q::::::D::::::::G:::LI::::::::::::::::::
NP2514A         :::::::::::::::S::::::::::::::::LH:PND:::::::::D:::::::W:::A
rrnAC3309       :::::::::::::::::::N::::::::::::LG:R:RD::::::::::::::::W:::A
Hut2979         ::K:::::::N::E:A:::N:::::::::::E:D:E:R:::::::T:D::::::TW:::A
Hmu2283         :::::::::::::::::::N:::::::::::::D:A:Q:::::::T:::::::::W:::A

consensus       DMSRNMEVIDETLEAAVSEPAYRVEDVCGDAAERLLEKHDYTTTAEVRMEAELVTREDTP
#oth            .....1311..3..311333422..21..12..1.12..1..24.1.2.3.11141.3..
VNG1901         ::::::R:::::::D::R::I::::EM::EV::::::::::::::T:E:N:::ML::E::
hla0996         :::::LAT:::I::EITR:E:::::E:::::::::::::::::::::S:S::::::::::
HQ3317A         ::::::Q:::::::::::GSVS::::M:::V::::::::E:::::T:E:T:D::MH::::
HVO_2348        ::::::Q::::V::::::::::::::M:::::::::A::E:::::::S:T::::V:::::
Hbo2031         ::::::Q::::I::D::A::T:::::M:::T:::::A:::::SK:::::T::::L:::::
NP2514A         ::::::::V::M::E::::::LS:::::::V::::I:::::::Q::::::::YMI::E::
rrnAC3309       ::::::::::::::T::::E:::::::::::::L:::::::::K::::::::Y::H:S::
Hut2979         :::::::::::::::::DNTG:::::::::::::::D:::::DR::::::::Y::::R::
Hmu2283         :::::::::::::::::RDEVSG::A:::E::::::D::::::N::::::::Y::::E::

consensus       ASELPTQSTADIIASATATEEG-TREEIGARVTGMTVCPCSQGMSASRARDVLADLDVDD
#oth            11234..3.14.2...1.22122.1..1.12.2.........1.1221..32163.3122
VNG1901         ::D::::G:I::::::::Q:DAP:::::::::V:::::::::Q:MSET::RK::E:G:GE
hla0996         ::GIE:::::T:V::::::::D::::::::E::::::::::::::E::::EK::::G::E
HQ3317A         :::::::N:IS:L::::::D::::::::::E:I:::::::::::::::::::MH:::IE:
HVO_2348        ::G:S:::::E::::::::D::::::::::E:V::::::::::::::::::::Q::A:::
Hbo2031         ::::Q:::::N:::::V:::D:::::::::E:V::::::::::::::::::::R::::E:
NP2514A         :TDR:::A::::::::::D:D:N::::::CH:V::::::::::::E:::::::EG::::R
rrnAC3309       :::MA:::::::::::::::D:::S:::::::::::::::::::::::::ET:KQ:N:E:
Hut2979         E:DR:::::::::::::::D:::::::L:::::::::::::::::E::::QT:N:::::R
Hmu2283         :::R::::::::V:::::DA::::::::::::::::::::::::::A:::ET:RG:::::

consensus       ETIEEFLEEVPQPGHSQRGHATLTVETDGSPDVDLRDLIDVARDSMSARIYNLAKRPDED
#oth            12223..251..1...........1224.3.111.422231..11...1...2.......
VNG1901         DAVR:::RD:::A:::::::::::::AG:D:::N:M::VS::::::::::::T:::::::
hla0996         ::T:::::A::::::::::::::::T:::H::I:::::::::::::::::::M:::::::
HQ3317A         ::::T:::Q::::::::::::::::TA::::::::IE:A:I:::A:::::::::::::::
HVO_2348        D::::::DK::::::::::::::::::Q:::E:::M::::I:::::::::::::::::::
Hbo2031         ::::::::Q::::::::::::::::::E:::::::I:IV:I:::::::::::::::::::
NP2514A         D::DA::::::::::::::::::::::S:D::::::T:::I:::::::::::::::::::
rrnAC3309       DV::::::TN::A::::::::::::QS::A:E:::NE::E::::::::::::::::::::
Hut2979         :::DT::D::::A:::::::::::I:S::::::::::V:A::::A:::H:::::::::::
Hmu2283         :::DS:::::::::::::::::::I:SE:A:::::L:V:E:::E::::::::::::::::

consensus       HMTYEAHADAKFVEDCVRSMAEGVVEEFDHLPDDAVVRMKQSNDESIHQHNAHAERVATL
#oth            1..111.21.........11.323234231.4211112.1................1142
VNG1901         :::::S::N::::::::::::R::::::::::E::::T::::::::::::::::::::EF
hla0996         ::::::::::::::::::AL:::TI:::G::S::::IH::::::::::::::::::EV:M
HQ3317A         Y:::H:::::::::::::::::Q::NS:E::D::::::::::::::::::::::::EV::
HVO_2348        ::::H:::N:::::::::::::LSL:AL:::G:::::H::::::::::::::::::EV::
Hbo2031         ::::H:::N::::::::::::DQ:LT:::::A:::::H::::::::::::::::::::S:
NP2514A         :::F:S:S:::::::::::::N:LL::YPD::::TI:::E::::::::::::::::::EF
rrnAC3309       :::::::K::::::::::AL:::::NT:PD:::::::T::::::::::::::::::::Q:
Hut2979         :::::::::::::::::::L::::::T:PD::EN::I::E::::::::::::::::::RF
Hmu2283         :::::S:KN::::::::::::::::DR:::::A::I:T:::::::::::::::::::::F

consensus       GDLRDEVDAD-------------------------------
#oth            22.24.16453111111111111111111111111111111
VNG1901         :Q::E::GSGE::::::::::::::::::::::::::::::
hla0996         ::::::L::E:::::::::::::::::::::::::::::::
HQ3317A         EQ::A::S:S:::::::::::::::::::::::::::::::
HVO_2348        :Q::::L::-:::::::::::::::::::::::::::::::
Hbo2031         :E::::LEERD::::::::::::::::::::::::::::::
NP2514A         :Q::R::RD-:::::::::::::::::::::::::::::::
rrnAC3309       D:::Q::SE::::::::::::::::::::::::::::::::
Hut2979         :::T:::NG:AEGGNPEPADSGVAGTETDAVDRRTNGSGDR
Hmu2283         :::EA:LAD::::::::::::::::::::::::::::::::