[J] (-) COG1500 Predicted exosome subunit 9 genomes BUD0589 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1276 rrnAC1173 HVO_1344 Hbo0206 Hmu1461 Hut0462 hla2471 NP3740A HQ2517A

Pairwise sequence scores
Consensus score	1826	VNG1276	NP3740A	Hut0462	rrnAC1173	Hmu1461	hla2471	HQ2517A	HVO_1344	Hbo0206
1454	VNG1276	1818	1331	1458	1357	1422	1451	1367	1386	1395
1621	NP3740A	1331	1820	1518	1566	1543	1504	1478	1471	1551
1614	Hut0462	1458	1518	1830	1606	1562	1529	1464	1476	1475
1671	rrnAC1173	1357	1566	1606	1846	1686	1477	1519	1493	1560
1635	Hmu1461	1422	1543	1562	1686	1832	1448	1480	1464	1515
1603	hla2471	1451	1504	1529	1477	1448	1818	1461	1510	1563
1584	HQ2517A	1367	1478	1464	1519	1480	1461	1819	1485	1588
1619	HVO_1344	1386	1471	1476	1493	1464	1510	1485	1787	1587
1660	Hbo0206	1395	1551	1475	1560	1515	1563	1588	1587	1812

242 symbols
consensus       MISLDEAVTARLESHGERFEVLVDPDAALAIKRDEFDGDLEDVIAAEDVFEDASRGDRPA
#oth            .....1.......1..2.....1......211.11.112111....1....1.11....1
VNG1276         :::::D:::::::T:::::::::::::::EMR::::::E:T:::::R::::N::::::::
NP3740A         :::::::::::::::::::::::::::::S:::G::::::::::::::::::::S::::P
Hut0462         :::::::::::::T:::::::::::::::SM:::D::::::::::::::::N:::::::P
rrnAC1173       ::::::::::::::::Q:::::::::::::::::D::D:::::::::::::::::::::P
Hmu1461         ::::::::::::::::Q:::::::::::::::::::::E::::::::::::::::::::P
hla2471         ::::::::::::::::::::::I:::::::M::G::E:N::::::::::::N::::::::
HQ2517A         ::::::::::::::::::::::I::::::EM::::::D:I:::::::::::N:A::::::
HVO_1344        ::::::::::::::::A:::::I::::::S:::G:::::::E::::::::::::::::::
Hbo0206         ::::::::::::::::::::::I::::::::::G::E::::E::::::::::::::::::

consensus       ENDLEEVFGTTEPLEIIPEVIKRGEIQITAEQRREMQEQKHKQLINRIARNAVNPQMDDA
#oth            .23.23..2..1.13...2.133.......1..12.111.222.123.2...1....121
VNG1276         :S:::T:::::::::::::::GQ:::::::D::EA::QR:KRS:::T:S:::I:::::G:
NP3740A         :SA:::::E::D::::::A:::::::::::::::K::::::N::V:K:::::::::::::
Hut0462         ::A::::::::::::::::::QD:::::::D:::::::R::RE:VQ::T:::::::::::
rrnAC1173       ::M:::::D::::MA:::::::::::::::D::::::::::::::Q::T:::::::::::
Hmu1461         ::S:T:::D:::::::::::::Q:::::::D::::::::::R:::QQ:T:::::::::::
hla2471         :E:::T:::::D::::::::VE:::::::::::E::M:R::N::VTT:T::::::::::S
HQ2517A         :E::KA::E:::::S:::T:V:D:::::::::::::::::R:::::Q:::::::::::N:
HVO_1344        :::::K:::::D::Q:::::V:K:::::::::::::::::R:S::::::::::::::N:S
Hbo0206         :::::T::E::D:M::::::V:::::::::::::::::::R:::::T:::::::::::N:

consensus       PHPPERIERALEEAGFRVDPMEPVENQVDDALDALRPVIPIRFDEVTVAVQLPADYAGSG
#oth            ....1...1..1.11.31...11114.1.1..11....1..1.2.111...2.121..22
VNG1276         ::::D:::S::D::::T::::T:ADE::::::E::::::::::E:M::::::::::::::
NP3740A         ::::::::::::::::Q::::::::::::E:::D::::::::::::VM:::V:::::::A
Hut0462         ::::D:::S:::::::QI:::::::T:::::::::::::::::::::::::::P::::::
rrnAC1173       ::::::::S::::TD::::::::::A:::::::::::::::::::::::::V:::::::A
Hmu1461         ::::D:::S::::TD:::::::::D::::::::::::::::::::::::::V::::::AA
hla2471         ::::::::::::::::QI::::::::::::::E::::::::::E:::M::::::::::::
HQ2517A         :::::::::::::::::::::::::S:I:::::D:::::::::::::::::V::SD::KT
HVO_1344        ::::::::::::::::KI:::::::S::::::::::::L::K:A::::::::::E:::::
Hbo0206         ::::::::::::::::K:::::K::S:::E:::::::::::::::::::::I::::::KT

consensus       QAQIREFGDLEREEWQNDGSWVGVITFPAGLQNDFYDLVNEHTSGEAETRIVKDEDEIST
#oth            .122.21.1.11....3....1..31....1.1111241.1411.2111222.11.1142
VNG1276         ::KL::::E:::::::A:::::::::::::M:DE::GR:::VSE:NG::SV:::K::LK:
NP3740A         :::::Q::E:QS::::S:::::::LK:::::::E::::::::::::::::T:::::::G:
Hut0462         ::K::::::::S::::S:::::::L::::::::::FE:A::VS::::::::I::::D:K:
rrnAC1173       :::::Q::::::::::S:::::::M::::::::::::V:::::::::::::I::::D:::
Hmu1461         :SR::Q::::::::::A::::I::::::::M::E:::V:::::::::::Q:::::::::I
hla2471         ::::::::::::::::::::::::L:::::::::L::::::V::::GDA:VI::K::LR:
HQ2517A         :::V::Y:::::::::P:::::::V:::::M::::::::::L:::::::::L:NK:::::
HVO_1344        :::::SY:::::::::::::::::::::::M::::::K::NI:::T:::::::::::L--
Hbo0206         :::V::Y:::::::::::::::::V::::::::::::M:::Y::::::::::::K::L::

consensus       R-
#oth            11
VNG1276         ::
NP3740A         ::
Hut0462         ::
rrnAC1173       :G
Hmu1461         ::
hla2471         ::
HQ2517A         ::
HVO_1344        -:
Hbo0206         ::