[S] (-) COG1556 Uncharacterized conserved protein 7 genomes BUD1223 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG6381 pNG7018 HVO_1693 Hbo3143 - Hut1052 hla0625 NP1724A -

Pairwise sequence scores
Consensus score	1240	Hut1052	NP1724A	pNG7018	VNG6381	hla0625	HVO_1693	Hbo3143
763	Hut1052	1277	548	520	537	552	565	534
727	NP1724A	548	1267	496	575	579	520	546
674	pNG7018	520	496	1234	501	516	560	594
926	VNG6381	537	575	501	1374	1050	654	657
946	hla0625	552	579	516	1050	1226	645	647
877	HVO_1693	565	520	560	654	645	1289	972
870	Hbo3143	534	546	594	657	647	972	1263

196 symbols
consensus       ------------------MSASPIATFESSLERLGVEWTRTSADEFESTLAELLDEPAVG
#oth            11111111111111222223322212.15112323133321233321431423244.11.
Hut1052         ::::::::::::::MSSTQTE::VER:VT:::E:D:T::::D::AV:::V::::::::::
NP1724A         :::::::::::::::::::P::T:E:::RAVG:TADGCH::DTET::E::S:VVET::::
pNG7018         ::::::::::::::::::-ME:KR:S::GA::A:::TVSS::ES:L:AAVT:AVT:::::
VNG6381         MVGPGRKHPLTVGTIFWD:::E:::::::::DEV:::LV::T::::A:::SP:::A:T::
hla0625         ::::::::::::::::::::VE::::::::::DV:::LV::T::::::S::P:::S::::
HVO_1693        ::::::::::::::::::::TGTV::::D:::::E:G::HA:P:GLADV:E:HCP:::::
Hbo3143         ::::::::::::::::::::TGTV::::A::D::D:D::HA::A:::TV:RDVCSD:TI:

consensus       VPL-------PFDGVSLPD-AVETDPSPADLRAAATGVTAAGLGIADYGSVVIQGTADGE
#oth            3311111111232423213141321.2211123.41...3.21.11...11323234413
Hut1052         I:I::::::::I::A:::S:::D:::D::AV::::::::P:T:::::::::LLPSDDH:S
NP1724A         T:::::::::S:E:::FGEV:I:M:::::A:T::E::::P:::::::::T:T:D:R:A:D
pNG7018         :A:DETVGDGT:SL:ET:-:-ITV::T::A::E:T::::G:E::VG::::L:LSM:EQAS
VNG6381         TS::::::::::ET::::::S::::::I:::E::::::::::Y::::::::I:::GT:::
hla0625         A:::::::::::ENL:::::T:::E::V:::E::S:::::::Y::::::::::::G:N::
HVO_1693        :E:::::::::Y:::D::::W:N:::T:::::G:NA::::::::::::::::V:::P::I
Hbo3143         ::::::::::TH:-:T::::W:N:::T:D:::T::::::E::::::::::::L:::P::I

consensus       EPVSLFPDRHVAVVAESDIVPDMDAAFDRLGEDIR-DGHGSAIIATGPSATADMGALVKG
#oth            111..1423.1211432.1312.321133132422142522311.......1...31.3.
Hut1052         GLL::::ET:IP::S:R:V:GT:AD::GE::PQL:::DR:DV:::::::::S:::EI:R:
NP1724A         :L:::Y:P:::V::D::::::::A:::E:FEQT:GG::PD:CVL:::::::::::T::E:
pNG7018         :L::::VE::::ILY:E::Q::::::VAE:D:RFT:ETN:::::::::::::::::::::
VNG6381         :::::YA:E::::::A::VL:::::T::Q:A:::::N:V:QS::::::::::::::::T:
hla0625         :::::YV:E::::::A:::L:::::T::::A:::::G:T:Q::::::::::::::G::::
HVO_1693        ::::::G:L:I::LRR:::::G:PE:::W:::EF::T::S::::::::::::::::::::
Hbo3143         ::::::S::::::LRK:::A:G:G:::EW:::TF::T::S::::::::::::::::::::

consensus       AHGPKDVHVVILEE--
#oth            1...32.1.1211431
Hut1052         V:::T::::::V:Q::
NP1724A         V:::TE::::VV:R::
pNG7018         :::::E:::I:V::ED
VNG6381         ::::M::T::L::GK:
hla0625         ::::I::T::L::DR:
HVO_1693        ::::::::::::D:::
Hbo3143         :::::A::::::D:::