[S] (-) COG1738 Uncharacterized conserved protein 7 genomes BUD1222 7 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2264 rrnAC2855 HVO_0183 Hbo1311 - Hut1732 hla0140 NP1354A -

Pairwise sequence scores
Consensus score	1706	NP1354A	hla0140	HVO_0183	Hbo1311	Hut1732	VNG2264	rrnAC2855
1194	NP1354A	1782	1049	1001	1021	856	945	1012
1235	hla0140	1049	1747	1109	1039	826	1005	977
1340	HVO_0183	1001	1109	1751	1309	945	1043	1027
1273	Hbo1311	1021	1039	1309	1760	872	1017	965
1103	Hut1732	856	826	945	872	1719	966	1134
1265	VNG2264	945	1005	1043	1017	966	1728	1031
1230	rrnAC2855	1012	977	1027	965	1134	1031	1694

262 symbols
consensus       --MSEERS-----------------PVGQVALIALFVTALATAQLTASKLLAIPLPFA--
#oth            1112342323232111111111111333212.321.131.3.1.1..1.123231.3111
NP1354A         MRTMSDTARRPSP:::::::::::::A:A:F:A:V::AS::::::::A:V:SFD::::::
hla0140         :::::GTARAAGGEGPFAADPLDRSA:AA:G::T:::V:::::::::A:VI:L:::::::
HVO_0183        :::::G:::::::::::::::::::AI:::::VG::::::T::::::::::S::::S:VG
Hbo1311         :::::T:F:::::::::::::::::G::::::L:::IM::T:::::::::::::I:D:VG
Hut1732         ::::A:::ATPL::::::::::::::LARLG:::V:::::I:S:V:::::VG:DI::S::
VNG2264         :::TRNDT:::::::::::::::::::T:::::G::::::V::::::::::LFE::VS::
rrnAC2855       :::TS::::::::::::::::::::EAVR:G:V:::::::V:S:V:::::::FS:::S::

consensus       -LPLAGATLLLPGAALAYALTFFASDCYAELYGRRAAQVMVNVGFAMNFVLLALVWSTIA
#oth            2..32.32142.1..1...1..1.....2....1131122...1.21.121.1..12124
NP1354A         :::::::E:A::::::::::::L:::::T::::K:::::L:::A:::::LV::::::::L
hla0140         :::VV:PEIT::::::::::::L:::::::::::::T::V:::A:LA::LV:::::::L:
HVO_0183        E::FV::AI:M:::::::::::::::::S:::::::::::::::::::::::G:::::::
Hbo1311         S::IV:T:I:M:::::::::::::::::S::::::P::L::::::::::I::::::G::F
Hut1732         ::::::S::IV:A::F:::V::::::::::::::SE:TKL:::A::::::::G:::LA:E
VNG2264         :::VT::A:V:::::::::V:::::::::::::::D:::::::::V::L::::::Y::VR
rrnAC2855       ::::::S::V:::::::::::::::::::::::::::T:V:::::::::::::::::::F

consensus       APA----ANPEDAAAFATVLGSSTNIVAGSLLAYLVSQNWDVVVFHAIRDRTDGSHLWLR
#oth            ..2213324123333.331.322221111.11..11...2..22..41112.1343....
NP1354A         :::APSSID::---S:EL:::A::::::::::::V::::Y::::::RLGEL:::D:::::
hla0140         ::G::::ID::I::::D:A::PAA:V::::::::V:::::::::::::::::GRGM::::
HVO_0183        :::::::::::F::Q:::::S:G::V::::::::::::::::::::G::EL::::L::::
Hbo1311         :::::::::::F:GQ:R:::A:G:::I::::::::::::::::A::S::EL:GS::::::
Hut1732         ::I::FVGS:V:QSP::S::::::GV::::M::::::::L::FT::WL::::::RL::::
VNG2264         ::IAPFSGVGQ:--::::::L:AG::::::::::V:::::::IA::::::::GA::::::
rrnAC2855       ::GLPQA:Q:V:L:::RN:::A::A::VA::S:::I::::::F:::WL::Q:::KK::::

consensus       NIASTATSQAIDTVIFVGVAFWAAP-VLGIGDPLPAAVLLALIVGQYLLKLAIAVVDTPF
#oth            .12..11..32..2..1211.332154215.4431435322.32....1.221.23...1
NP1354A         :::::G:::LL::::::SI:::VF:QYV:L:PE::::AVVS:M::::::::L::::::::
hla0140         ::::::S::::::A:::::::Y:::L:::S::::::S:::::GL:::::::::::L:::I
HVO_0183        ::V::::::::::::::::G:Y:::T::::::V::WN::VG:A::::::::L::I:::::
Hbo1311         :::::::::::::F:::S:::AL::RFF:::EA::ENII:G:MI:::::::L::L:::::
Hut1732         :VG::::::FV:::::IT:::----:I:FK:--I:LGDAAG:::::::V:IGV::F::::
VNG2264         ::G::::::I:::::::T:::::::VL::V:Q:RTP:Q:::::::::::::::::G::::
rrnAC2855       ::G::::::L::::::I::G:----:::FQ:--V:PSEA:::::::::::V::::L::::

consensus       VYAVVGAVRR-RDVGADPAAAD
#oth            ..22132215354544544522
NP1354A         ::LIT:::::YT:PAPS::R--
hla0140         ::L::::::E:-----------
HVO_0183        ::GT:ALL:GDDESST:GWV::
Hbo1311         ::L::SL:GNSA:D:Q::W::E
Hut1732         :::::HF::D::E:::NVVPS:
VNG2264         :::::A:A:S::GL::PAP:::
rrnAC2855       ::::::FA:::NN:VTT::S::