[S] (-) COG1860 Uncharacterized protein conserved in archaea 9 genomes BUD0778 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1401 rrnAC1064 HVO_2851 Hbo2617 Hmu1636 Hut1107 hla0955 NP3406A HQ3004A

Pairwise sequence scores
Consensus score	1193	Hut1107	VNG1401	HQ3004A	NP3406A	Hmu1636	rrnAC1064	hla0955	HVO_2851	Hbo2617
914	Hut1107	1194	747	761	794	823	831	775	775	790
908	VNG1401	747	1197	806	786	836	802	760	867	839
876	HQ3004A	761	806	1208	807	822	806	805	874	855
926	NP3406A	794	786	807	1157	855	873	815	813	859
1025	Hmu1636	823	836	822	855	1205	969	808	891	860
1034	rrnAC1064	831	802	806	873	969	1186	836	895	893
897	hla0955	775	760	805	815	808	836	1184	850	863
1001	HVO_2851	775	867	874	813	891	895	850	1197	939
981	Hbo2617	790	839	855	859	860	893	863	939	1183

153 symbols
consensus       MTTVTLIGTRLAEPGTEFVYRGESSACEGCPYRDQCLNLTEGVRYRVTDVRENGQTLDCA
#oth            1251..2.5..133.31...4.1232.1.....5.....42.3..21131.23223.1..
Hut1107         ::QI::L:::::::::::::Q:::P::D:::::::::::DV:R::H::SI:DGAS:::::
VNG1401         -MPI::L:P:::D:::::::H:PADD:::::::Q:::::::::::E::::::G::V::::
HQ3004A         :SH:::::D:::ST::::::E:::V::::::::K:::::::::::EI::::DD::L::::
NP3406A         :S::::L:E::::V::::::G::TD::::::::E::::::::R:::::G::DS:-::E::
Hmu1636         ::::::::S:::TA:E:::::::A:G:D::::::::::::::::::I:::::S::I::::
rrnAC1064       ::::::V::::::V:A:::::::A:G::::::::::::::T:N:::I:N::QS:::::::
hla0955         ::::::::::::DT:R::::Q:::PD:::::::S:::::S::T:::::GI:::A::::::
HVO_2851        ::S:::V:A::TD:::::::H::::::::::::R:::::I:::::::L:::::T:V::::
Hbo2617         ::K:::::D:::::::Q:::::P::::::::::K:::::EV::::E::GI:::A:L::::

consensus       VHDEGVRAVEVEPAPVQANVPSKGAYAGSKASLAGPCPHTECPSHEYCEPAGADFDEEYR
#oth            ..14.13.11...1215.1.5234....1223.4.2..112....22.1.2..2.13112
Hut1107         ::::::T:I::::::I::::T:QS::::::VE:E:T:::E:::::GL::::::::ETP::
VNG1401         :::::AV::D:::TTIP:T:::::::::::GK::::::::::::::F::::::S::T::Q
HQ3004A         :::T:::::::::TS:V:::ATRE::::G::E:P:S::::::::::::V:D::E::T::Q
NP3406A         :::T::T:::::::::L:::DANA:::::::::V::::Y:::::::F:::D::::::::Q
Hmu1636         :::S::K::::::::IK:::SA:::::::S:T:E::::Y:G::::::::::::S::::::
rrnAC1064       ::EN:::::::::::I:::::::::::::::::P:::::::::::P:::::::E::::::
hla0955         :::A::::::::::::P:::L::Q::::GRV::::::::::::::G::V:D:::::D:RV
HVO_2851        ::::::::::::::::T::::::::::::::::Q::::::::::::::V:E::E::Q:::
Hbo2617         :::T::::::::::::V:::::::::::::::::::::::Q:::::::V:E:::::::::

consensus       IDEVVGDPPHDYCMLDRDLTLVEFAPPEE----
#oth            .5415.1...13.5...2.11.11312363121
Hut1107         ::S:I:::::E:::::::::K::L::::SE:::
VNG1401         :A:ID:E::::H:A::::::::::::A:R::::
HQ3004A         :ET:H:::::EH:Q:::E::::::K::DTTSN:
NP3406A         :T:::::::::::::::E:Q::Q::AE:-::::
Hmu1636         :::I:::::::::G:::::::::L:::::RSGR
rrnAC1064       :S:I:::::::::::::::::::LEA:G:::::
hla0955         ::Q:L:E::::V:A::::::::::RAEDG::::
HVO_2851        :HD:L::::::H:H:::N::::::E:AD:::::
Hbo2617         :A::R::::::F:Y:::::::::::AESD::::