[S] (-) COG1912 Uncharacterized conserved protein 9 genomes BUD0649 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0300 rrnAC1911 HVO_0781 Hbo0127 Hmu0662 Hut0553 hla2292 NP0906A HQ1165A

Pairwise sequence scores
Consensus score	1956	hla2292	HQ1165A	HVO_0781	NP0906A	Hut0553	VNG0300	Hmu0662	Hbo0127	rrnAC1911
1241	hla2292	2128	1016	1092	1115	1060	971	1094	1030	1071
1276	HQ1165A	1016	2020	1163	1038	1123	925	1068	1048	1207
1312	HVO_0781	1092	1163	2003	1115	1170	1070	1126	1150	1136
1373	NP0906A	1115	1038	1115	1986	1106	1046	1097	1158	1211
1470	Hut0553	1060	1123	1170	1106	1972	1112	1271	1219	1301
1370	VNG0300	971	925	1070	1046	1112	1820	1224	1108	1191
1487	Hmu0662	1094	1068	1126	1097	1271	1224	1927	1214	1289
1431	Hbo0127	1030	1048	1150	1158	1219	1108	1214	1961	1278
1541	rrnAC1911	1071	1207	1136	1211	1301	1191	1289	1278	1982

297 symbols
consensus       ----------MITLSSDFGSPYPAAMKGVILQRTDARLVDVAHDFPRQDVRAAAFWLREV
#oth            1111111111111121111321111....23362.1112.12.11..1.1121...1121
hla2292         ::::::::::::::A:::::::::::::::RRH:::E:I:::::L::G:P::::::::F:
HQ1165A         ::::::::::::::::::::::::::::::::T:::::I::T:EL:::::::::::C::T
HVO_0781        ::::::::::::::A::::LA::::::::V:S:::G::::::::L::::::::::::::T
NP0906A         :::::::::::::::::::T:::::::::::KQC:::::::::::::::::ST::::TQT
Hut0553         :::::::::::::::::::T:::::::::LASG:::::I::S:E::::::::::::::::
VNG0300         ::::::::::---------------::::V::T:::::::I:::L:::::::::::::::
Hmu0662         :::::::::::::::::::::::::::::::RDS:::I:::S:E::::::PG::::::::
Hbo0127         MARGGRETDT:::::::::T:::::::::L:S::::::::::::::::::::T:::::::
rrnAC1911       ::::::::::::::::::::::::::::::C:A::::IE:I::::::::::::::::TQT

consensus       LPYFPPAVHLVVVDPGVGTDRDAIVVRAGDHALVGPDNGVLLPAARALAGDADD------
#oth            2.2..2.1.22.1......1.3.22211.2.2211....124.21.42146643441111
hla2292         ::E::::::CA:I::::::::::L:::::S:V::A::::LAM:P:::::REKEQD:::::
HQ1165A         I::::S:::VI:::::::::::::MI:V:::::I:::::::R:V::Q:SEQLQ:ETMGLK
HVO_0781        :::::::::::::::::::::R:V:L:V:::VF::::::::R:P::RV:AEL::D:::::
NP0906A         ::E:::::::I::::::::G:::L:::::::V:::::::::F:P::::::GD::YS::::
Hut0553         ::H::::::::::::::::::A:LAI:::E:V::::::::::::::K::DA::SEA::::
VNG0300         V:::::::::A::::::::::S:V:::::S::I:A:::::AV::::RI::::--::::::
Hmu0662         :::::::::C:::::::::::A:::::V::::I:A:::::A::::::I:D:G--::::::
Hbo0127         :::::A:T:::::::::::::A::::E::E:TF:A:::::V:::V:EI::----::::::
rrnAC1911       :::::::::C:::::::::::::::::::::::::::::::::V::E::ETEN:AP::::

consensus       DDIEVFEIDYDDPASATFHGRDVFAPAAAAIH------------EAGVDTLEALDRLE--
#oth            35213154234214.5..........3..4211111111111112425443655444522
hla2292         EN::A:VV:VGE:::E::::::::::T::R:RTALDDNPAKATP::VSE::A:M:D:S::
HQ1165A         NN::Y:RYE:TE:Q::::::::::::::::::::::::::::::DC:IASV:T::AVTSV
HVO_0781        APV:AY:::VPN:E:T:::::::::::::DA:::::::::::::V::ASA:GSV::F:PI
NP0906A         A::DAYQL:MG::R:S::::::::::G:::V::::::::::::::T:I:R:PE::C:S::
Hut0553         :A::G::YA::::E:V:::::::::::::T:::::::::::::::::RSQF::G::FG::
VNG0300         A::D:::::VE::::::::::::::::::D:::::::::::::::R::::FDQYPEY:::
Hmu0662         :V::::::ET:E::::::::::::::M:::V::::::::::::::I:::S:HEVAD:V::
Hbo0127         ::FD:YDVA:::VP:N:::::::::::::NV:::::::::::::D:S--AVTDIE:IT::
rrnAC1911       :TF:::TWA::::::T::::::::::::::V:::::::::::::DT::::I:T:SEID::

consensus       PAEDYVDLTFPAPTVD----DDG--ATGEVLVVDDFGNAITNVPGEVLADRFGEQVRVNG
#oth            12545342511314251111424331312.111.2...31..2..442524312615121
hla2292         ::T:P:::VL:D:S:ERDDAG:PVAVD::::AI:R:::VV::::::LIRG:--DW::I::
HQ1165A         ::TAT:QCK::SA:I:::::A:DTS:::::::I:::::I:::I::SF::::A::MAT:GT
HVO_0781        :VGSLSECRLSEA::S:::::::RE:::::::::::::C::::::AFVR:AA::T:W:::
NP0906A         ::SSV::::L:S:EF:::::G:A::V:AA::A::::::V::::::T::G:S--DR:V:D:
Hut0553         :V:A:EG::::D::IR::::E:::::D:::::::::::::::::::I:TE::::A:T:::
VNG0300         :TA::ERVS::::A:T:::::G::::A:T:IA::G:::::::L:::IV:::V:DT:E:D:
Hmu0662         R:DG:EE:A::E:::S::::QT::::S:A:::::G:::::::::::AIE::::Q:::I::
Hbo0127         :V:EF::::::::V:G:::::GQ:::::::::::::::VV:::::R::DGL--:::S:::
rrnAC1911       :T:::A::R:::AA::::::G::::::::::::::::::V::I::::::GQ:::V:S:D:

consensus       EEAPVRRTYAAVDPGDRLVTVGSHGNVELAVNRGRGDEAFGVSAGDTVRLRW-----
#oth            2631163213422524311......2..21..3.1.122.41431231324642221
hla2292         :LT::AE:FG:::S:::::::::::Y::CD::D::::G::DLRP:ES:::VADNVSL
HQ1165A         TT:E:TS:F:D::T::P:L::::::F::CD::H:Q:T:I:ELEVK:::QI:F:::::
HVO_0781        :SV::G::FE::AR:EK:::::::::::CD::H::::::::LAP::R:E::VD::::
NP0906A         ::R::VDS:DHAAT:TAV:::::::::::::::::::D:::::::E::::DGIDAA:
Hut0553         VW::AK::::M:EADN::::::::::::::::Q:::::R:S::T:SRI::::T::::
VNG0300         VAT::::S::HT:::Q::L::::::::::::::::::D::::::::E:TVV::::::
Hmu0662         :P::::::::T::::Q::::::::::::::::::::::::R:G:::R:E:SY:::::
Hbo0127         :P:::GDS::::E:::::::::::::::F::::::::D:::LAV::::T:EY:::::
rrnAC1911       V::::H:A:::::KSQ:::::::::::::::::::::::::::T::::TISLC::::