| ||||||||||||||||||||||||||||||||||||||||
| Pairwise sequence scores | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Consensus score | 9823 | VNG2338 | HQ3461A | hla0374 | Hbo1434 | HVO_0065 | NP0476A | Hut2322 | rrnAC2691 | Hmu3098 |
| 7976 | VNG2338 | 10596 | 6993 | 7394 | 6723 | 6747 | 6758 | 6572 | 7334 | 7392 |
| 7741 | HQ3461A | 6993 | 17420 | 7296 | 6843 | 7285 | 6390 | 6343 | 6981 | 6917 |
| 8242 | hla0374 | 7394 | 7296 | 10511 | 7377 | 7295 | 6891 | 6770 | 7415 | 7548 |
| 7851 | Hbo1434 | 6723 | 6843 | 7377 | 9203 | 7572 | 6967 | 6725 | 6800 | 6909 |
| 7930 | HVO_0065 | 6747 | 7285 | 7295 | 7572 | 9258 | 6833 | 6728 | 6832 | 6953 |
| 7571 | NP0476A | 6758 | 6390 | 6891 | 6967 | 6833 | 9187 | 6837 | 6930 | 7031 |
| 7546 | Hut2322 | 6572 | 6343 | 6770 | 6725 | 6728 | 6837 | 9121 | 7161 | 7262 |
| 8184 | rrnAC2691 | 7334 | 6981 | 7415 | 6800 | 6832 | 6930 | 7161 | 10680 | 8508 |
| 8412 | Hmu3098 | 7392 | 6917 | 7548 | 6909 | 6953 | 7031 | 7262 | 8508 | 10580 |
2318 symbols consensus MREADERYFARLEDRLDEAFDVARAAKERGGDPKPEVEIPVAKDMADRVENILGIDGVAE #oth 1124122..321.35.14.332.24.142.4..3231...2.1..........1.11... VNG2338 ::PT::T::ET::TG::D::E::E::R:::E::T:N:::::::::::::::::::::::: HQ3461A ::D::KQ::ET::SH:EQ::AR::Q::GQ:Y:::::::::::R::::::::::A:PD::: hla0374 ::PD::::::QI:::::::W:::E::::Q:H::::KI:::I:R::::::::::::::::: Hbo1434 VH:D:::::::I:::::::::L:::::GQ:R::Q:::::::::::::::::::::P:::: HVO_0065 V::EET:::R:I:A:::::::L:E:::AT:Y:::T::::::::::::::::::::::::: NP0476A :::D::Q::R:::SD::T:LS:::E:RK:::::TEDI:::I::::::::::::::::::: Hut2322 ::D:::::::::::E::T:M::::S:R::::::TTD:::::::::::::::::::::::: rrnAC2691 ::::::Q::ET::TQ:EA:::::ER:::::::::::::::T:R::::::::::::::::: Hmu3098 :::V:::::D:::SQ::D::E::Q:::R:::::V::::::T:R::::::::::::::::: consensus RVRELEG--EMSREEAALELVTDFVEGTVGDYDSRAGKVEGAVRTAVALLTEGVVAAPIE #oth .1.11121122....1..1.14..1314....1121..1..................... VNG2338 :::D:D:::::::::::::::A:::D:R:::::TD:::I::::::::::::::::::::: HQ3461A :I:::DD:::R::::V:::::::::::::::::T:E::I::::::::::::::::::::: hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::Q:::::::::::N:::::S:::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::D:N:::::::E:::::::::::::::::::::::: NP0476A ::::M:ADPDL:::::::::AA::ANDE::::ET:::::::::::::::::::::::::: Hut2322 :::D::::::::::::::A::E:::A:::::::TK:::I::::::::::::::::::::: rrnAC2691 :::::::::Q:::::::::::E:::::::::::::E:::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::S:::::E::::::K::::::::::::::::::::::::: consensus GIDRVEILENDDGTEFVNVYYAGPIRSAGGTAQALSVLVADYARSLLGIDEYKARDDEIE #oth ......2121...111111.......................1.2111.12131.33.22 VNG2338 ::::::VND:::::QY:A::::::::::::::::::::::::::AM::::AF:P:::::: HQ3461A ::::::::SD:::S:::::::::::::::::::::::::::::::::D::::S::T::T: hla0374 ::::::L::::::::::::::::::::::::::::::::::::::::D:::::P::V:V: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::E::::::I:V: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::D:::::::T::V: NP0476A ::::::L:::::::::I:I:::::::::::::::::::::::T:T:I::::::::N::T: Hut2322 ::::::::D:::::Q:::::::::::::::::::::::::::::T::D::::H:::E::G rrnAC2691 ::::::L:::::::::I:::::::::::::::::::::::::::A:::::Q::::EE::G Hmu3098 ::::::::::::::::::::::::::::::::::::::::::::A::::E::E:::E::N consensus RYAEEIDLYDKETGLQYSPKDKETKFIAEHMPIMLDGEATGDEEVSGFRDLERVDTNSAR #oth ..1..23...41.....1..12.121.1311.1........2...1.1.....1.1.11. VNG2338 :::::V::::S::::::::::A::T::T::C:V::::::::N:::D:::::::I::::P: HQ3461A :::::VS:::R::::::::::::::::TK::::::::::::N:::::Y:::::::::A:: hla0374 ::::::S::::::::::::::::S::::Q:::V::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 ::V:::N::::::::::::::::SR::::N:::::::::::::::::Y:::::::::::: NP0476A :::::LS:::D::::::A:::E:::::::::::::::::::::::::::::::::::::: Hut2322 ::V:::E:::ED::::::::E:::RH:TD::::::::::::G:::::Y:::::::S:::: rrnAC2691 :::::::::::D::::::::E::::::::::::::::::::::::::Y:::::::S::P: Hmu3098 ::::::E:::::::::::::E::S:::::::::::::::::::::::::::::::::::: consensus GGMCLVLAEGIALKAPKIQRYTRQLDEVDWPWLQDLIDGT--IGKDEDDA---------- #oth ......21....1.........12.21.2.........1.111.4145555511112222 VNG2338 :::::::::::::::::::::::N::::A:::::::::::::::------:::::::::: HQ3461A :::::::::::::::::::::::::A::E:::::::::D:::::S::HSNNS::::VKNG hla0374 ::::::A::::::::::::::::D::::::::::::::::::::::GGG:SDEAPENAGA Hbo1434 ::::::M:::::::::::::::::::::::::::::::::::::::DG:KAD:::::::: HVO_0065 ::::::M:::::::::::::::::::::::::::::::::::::::D:N:AN:::::::: NP0476A :::::::G::::Q:::::::::S:::::::::::::::::YKT:E:T:E:DA:::::::: Hut2322 ::::::::::::::::::::::::::D:E:::::::::::::::A::SEDET:::::::: rrnAC2691 :::::::::::::::::::::::N:::::::::::::::::::::::A:E:::::::::: Hmu3098 ::::::A::::::::::::::::N:E::::::::::::::::::::----:::::::::: consensus -ADDDGDDDADAESDTDDDDDGDE--ADE--PAGPPRADPSTKFLRDLIAGRPVFGHPSE #oth 321335236443331443534325543231243213.23234.1...........2...2 VNG2338 ::::ADE:TP::G::S:AT:E::APS:ST:DAEE::::A::D:::::::::::::::::K HQ3461A E::IVKT:KDTN::E:E:GI:N:DYNDSGLE::NS::::ATN:Y:::::::::::::::A hla0374 EG:::SE:T:GN:::G::A::A:S:ET:G::::::L:PKS:Q:::::::::::::T:::: Hbo1434 ::::::::E-E:DAED:EA:::ETPDSP:::::::A:V::A::Y:::::::::::::::: HVO_0065 ::::A:::GDE::AE::P:AEA:DAES:A:::D::T:VE:A::::::::::::::::::A NP0476A DS::GT:E::ADD::I::SSA:::E:::A:::S::::P::QK:::::::::::::::::: Hut2322 GGEE:E:GS::G:R::Q:::----:::ST::VD:::::E::K:Y:::::::::::S:::: rrnAC2691 :G:SAE:ANG:DAGEGA:::G::::::::::Q:::::VE:AD:Y:::::::::::S:::K Hmu3098 :G:E::EE::AD:G:DG:E:E:::TSTS:::DD::::::::::::::::::::::S:::: consensus AGGFRLRYGRARNHGFATAGVHPATMHLVDDFLATGTQIKTERPGKAAGVVPVDSIEGPT #oth 3.1.......1....1..1.....1..12...1.1...1........2.11...1.1... VNG2338 N::::::::::::::N::::::::::::L::::::::::::::::::::I:::::::::: HQ3461A ::A::::::::::::::::::::::::I::::I:::::L::::::::G::::::::K::: hla0374 ::::::::::::::::::G:::::::::::::::A::::::::::::H::I::::::::: Hbo1434 ::::::::::S::::::::::::::::::::::::::::::::::::G::I::::::::: HVO_0065 P::::::::::::::::::::::::::I::::I::::::::::::::G:::::::::::: NP0476A P:::::::::::::::::::::::A:::I:::::::::::::::::::::::::T::::: Hut2322 S::::::::::::::N::::::::::::::::::::::::::::::::::::::T::::: rrnAC2691 S:::::::::S:::::::::::::::::::::::::::::::::::::::::::T::::: Hmu3098 P::::::::::::::N::::::::::::::::::::::::::::::::::::::T::::: consensus VRLANGDVRRIDDPEEALEVRNGVEKILDLGEYLVNYGEFVENNHPLAPASYVVEWWIQE #oth .1....1..211.111.3321...1311.1......1...1....1.2..1.23...4.1 VNG2338 :K:::::::H:N::AD::D:::::AE:::V:::::::::::::::E::::::AP:::::D HQ3461A :::::::::C:N:::::EKLQ:::::::::::::::F:::I:::::::::A::F:::::: hla0374 ::::::E::::::::::K:I::::::V::::::::::::::::::::::::::Y:::V:: Hbo1434 :::::::::::::::::::::::::E:I::::::::F::::::::::::::::Y:::V:: HVO_0065 :::::::::::::::::K:LQ:::::::::::::::F::::::::::::::::F:::::: NP0476A :K::::::::V::::::::I:::::A:::::::::::::::::::::S::A:AP:::T:D Hut2322 :::::::::::::::::K:::::::SV:::::::::::::I:::::::::::T::::V:: rrnAC2691 :::::::::::::A::::A:::::::::::::::::::::::::::::::::T::::E:D Hmu3098 :K::::::::V:::A::I::::::::V::::::::::::::::::::V::::T::::R:: consensus FEAAGADVQALRDDPHVDLEDPTAEQALEWATEYDAPLHPKYTYLWHDVSVEAFDALADA #oth 12222121..14.1161..34.2323.34..332.21...4...21..22133241..1. VNG2338 LD:::::::::::S:Y:::TA:::D::MA:::D:::::::A:::::::ID::Q:R::::: HQ3461A :::SN::::::::::T::::S::F:N:MR::KKH:I::::A:::::::I::TE::H:::: hla0374 ::T:::::::M:::::::::H:DVDE::A::R:::C::::E::::::::::D::E::::: Hbo1434 ::::::PI:::E:::S::::H::P:R:F:::::::CH:::D::::::::::AE:E::::: HVO_0065 :::TE:N::::::::A::::E:SV::::S::::F::::::V:::::::I:::R::::::: NP0476A LA:::::::::A:S:R::::H:S::::::::ER:::::::E:::::::LD::R:E:::A: Hut2322 ::::::::::MT:SVEI::D:::PSR::Q::R::::::::::::VY:::::::I:::::: rrnAC2691 LA::::::::MQ:S::I::A::S::E:I::::::::::::::::::::::I:QVC::::: Hmu3098 :DD::G:::::Q::V::::A:::::E::R:::D:::::::::::C::::T:D:VG:::A: consensus VADGEIA--EADGATA------TAAPDDGTDGTLVLDRTEAVRETLEHLLVEHTQTEDTL #oth 223144333342235553133356855574324.322333533311.5..14.3133221 VNG2338 :::AH--::-------:::::::D:S::DDR:V::::H:TT::::::A:::T:H:GD::I HQ3461A ::A:::TMN:VSDTNSAS:GNTSLRANTN::D::TI:T:P:I:::M:R::I::H:DS:SI hla0374 ::A:DVV::-------::::::--------E:V:AIE:::TTQHA::S:::Q:VA:P:A: Hbo1434 :SS:R::DV::::GVVV:::::RPTDT:P:::I:E:::::D:TR:::Q:::::::::E:: HVO_0065 ::A:::VAA::::G:TAA:LEHDNE:EH:LE::::::NAPEI::A::::::A:R::DEA: NP0476A ASE:HW::::T:::QQ:::::::RP::GAAES:::VP:S:P:::A::V:::::::G:E:: Hut2322 I:::::V::TG:::::EP:GD:H:DRAGTAT:D:::P:S:IA:R:::S::::::::DAS: rrnAC2691 :E:AQV:::Q::::Y:DPEMDG::GDAHSD::A:::P:SD::QQ::::::IG:::D:E:I Hmu3098 :E:A:R::::T:::V:P::::::PS::R::::D:::PNR:P:AQ:::::::::::R:::I consensus RVPDWRPLVRSLGLTDDLE-------RTWSLDDLSEAARTW-----------------DD #oth 4124131.121..344423111111124.3342..33.1321111111111111111132 VNG2338 ::D::L::A::::V:ES:D::::::::E:--ET:::::AE::::::::::::::::::-- HQ3461A HI:A::A:AL:::IKIESDNDTGIGD:M:::T:::KH::KQ::::::::::::::::::: hla0374 :I:T::::A::::ID:G:R:::::::K:::A::::A:::E:::::::::::::::::::: Hbo1434 :I:E:::::::::::EE:::::::::Q::--::::AE::E:::::::::::::::::::G HVO_0065 :::V::::A::::::::R:::::::::::E::::::R::::::::::::::::::::::: NP0476A T:::AE:::::::::EG::::::::::::--:E::T:::SY::::::::::::::::::: Hut2322 I::T:::::ET::FN:::T::::::::P:T:S::::::::Y::::::::::::::::::: rrnAC2691 T:T::V::::T::FSRS::::::::::D:TRE::::H:::YGESESLDAIGVAEDAERE: Hmu3098 V::::E::::T::FDAA::::::::::E:::G::::H:::Y:::::::::::::::::A: consensus GDNAVEAVNEVAPFDVRERAPTRIGNRMGRPEKSESRDLSPAVHTLFPIGEAGGSQRDVA #oth 141.13.1..1...521........2.........4.1........1..211..3..222 VNG2338 -P:::R::::::::S:Q:::::::::::::::::::::::::::::::::D::::::::: HQ3461A :KS:IA::::::::Q::::::::::S:::::::::D::::::::::::::::::N::NLS hla0374 :E:::K:I::::::EI:::::::::::::::::::::::::::::::::N::::P::::: Hbo1434 :::::K:::::::::::::::::::::::::::::::::::::::::::::M:::::::G HVO_0065 ::::::::::::::N::::::::::::::::::::R:::::::::::::::::::::::G NP0476A :::::R::::::::E::::::::::C:::::::::K::::::::::::::::::::::I: Hut2322 :E::I:::::I::::::::::::::::::::::::E:E::::::::::::::::N::::: rrnAC2691 :Q::IK:I::::::Q::::::::::::::::::::R::::::::::S:::::::A::::: Hmu3098 ::::I::I::I:::RL:::::::::::::::::::E:E:::::::::::D::::A::S:: consensus DAARHADDMGDRPGEVEVEVGRRRCPDCGTETFRARCPDCGGHTEPHYVCPDCGSVVEPD #oth 2.14434334432.32413123.3.23.32412344.11.354.13411.51.342431. VNG2338 ::::Y:P::S:T:::IP:R::D:V::S:DEH:YES::::::DW:D:::E:R:::A:AT:: HQ3461A :::QSFG:NTE:-:QIS:QL:K::::Y:E:VG:ELQ:AE::R::::QF::RE:E::LS:: hla0374 E::GTM::S:H:-:RLDL::SD:V:::::EH:Y::Q:::::V::DL::E:G:::T:C::: Hbo1434 E:::ERNER:A:-:::N:L::D:Q::::::Q:YKNV::E:ET::::::E:EE::T::::: HVO_0065 :::::RGES:K:-:QIS:RL:Q:K:::::AFG:KSK::::::::::::E:D:::::I::: NP0476A E::T::ES:Q:T::::::Q::::Q::A:D:::::::::::ESV:D:R:::Y::NID:D:: Hut2322 K::G:::E:::A:::::L:::::::T::A:::YQ::::::N:I::TI::::::DRE:D:: rrnAC2691 K:TK:::::S:T::Q:::::A:::::::::::HQ:N:AE:S:T:::V::::::EAE::R: Hmu3098 ::TK::EK:N:QQ:L::::::::::R::::::::G:::::N:V:DAV::::::D:E:::: consensus ESGRVECPRCERDADPAQWQAIDLNEEYRDALENVGERESAFDILKGVKGLTSANKTPEP #oth .1..14.42.12424334454212343224.15411...311321.1.2..2.42.3... VNG2338 ::::::::N:G::L:NVTT:V::I:D::HG::RA:::::N:::Q:::::::L::E::::: HQ3461A :::::H:D:::::VTS:E::D:::HQR:::::DR:D::::S:E::::::::::S:::::: hla0374 :A:::::::::WEVTA:TY:EV:::DA::S:::T::::::::E:::::Q::::R:::::: Hbo1434 :::::F:E::::EVESPD:Y:::IGA:L:A::::L:::::SYP::::::::::S:::::: HVO_0065 :::::Y:E:::W:VES:E::DV:::S:::::::R::::::S:Q::::::::::::::::: NP0476A ::::AI::N:::E::AV:NRTVNVH::::S::S::::::N:::V:::::::S:EH:V::: Hut2322 ::::A::::::TI:S:TRMTT::VG:V:QQ:MDS:::::V:::V:::::::::KE:M::: rrnAC2691 ::::A::G:::TL:S:T:YKVL::Q:A:::::Q::::::T::EQ::A::::::EE:V::: Hmu3098 ::::A::AH::TM:Y:T:YE::::G::F::::GA:::::T::::V:::E::::KE:I::: consensus IEKGVLRAKHDVSAFKDGTVRYDMTDLPVTAVRPAELDVTADQFRELGYETDIHGDPLRH #oth 21..1....11111................1.113...111321.21..33..3.2..41 VNG2338 MA::::::::::T:::::::::::::::::::T::::::::G:::::::NQ:::::::E: HQ3461A L:::I:::::G::S::::::::::::::::::::K::::::AH::::::Q:::N:N::QF hla0374 :::::::::NG:TS::::::::::::::::S::AE:::I:::HL::I::::::D:E:::: Hbo1434 ::::::::::G::S::::::::::::::::S:::::::::::H::::::::::N:E::QF HVO_0065 :::::::::::::S::::::::::::::::::::E:::::::H::::::::::D:E:::F NP0476A ::::::::::G:::::::::::::::::::S::A:::::::::L:S:::::::::E::T: Hut2322 M::::::::::I::::::::::::::::::S:::::::::VE::::::::A::Q::::I: rrnAC2691 M:::I::::::::::::::::::::::::::::AS::::S:ERL:G:::TE:::::::T: Hmu3098 M:::I::::::::::::::::::::::::::::AS::::SV::L:G::::A::::::::: consensus DDQLVELRVQDIVLSDGAAEHMLKTADFVDDLLEQYYGLDRFYELDDRDDLVGELVFGMA #oth 1......2...1..11...2..12..3.1....221.1.231.2431.1.11........ VNG2338 :::::::::::V:::::::D:::::::::::::T::::::A::D:::::::::::::::: HQ3461A :::::::K::::::P:::::::M::::::::::::F:E:NQ::QI:E::::I:::::::: hla0374 ::::::::::::::::::::::::::G::::::::F::::::::FNE::::::::::::: Hbo1434 :::::::K:::::::::::::::::::::::::TEF:::EP:::VSE::::::::::::: HVO_0065 :::::::K:::::::N:::Q::MQ:::::::::D:F::::::::IEE::::I:::::::: NP0476A E::::::::::V:::N:::::::R:::::::::::::::EP::DAE::::I::::::::: Hut2322 :::::::N:::V::::::::::::::A:I:::::S:::::PY:::E:::::::::::::: rrnAC2691 E::::::K:::::::::::::::Q::R::::::::::::E::::F:::E::::::::::: Hmu3098 E::::::::::V:::::::::::Q::A:::::::::::::::::::::E::::::::::: consensus PHTSAAVVGRVVGFTSAAVGYAHPYFHAAKRRNCFHPET--W--D----W----I---VE #oth ......1...12...1.1................11122432221343213332134211 VNG2338 :::::::::::A:::::S:::::::::::::::::::::NV:FR:ESGE:HHDP:ETL:: HQ3461A ::::::::::I::::::::::::::::::::::::::::KI:FR:TDNE:HHET:QTF:: hla0374 ::::::T::::::::::::::::::::::::::::::::EIEYR:DAG::HRET:EKF:: Hbo1434 ::::::::::::::::::::::::::::::::::-----::-::-::::-::::-:::-- HVO_0065 :::::::::::::::T::::::::::::::::::-----::-::-::::-::::-:::-- NP0476A :::::::::::I::::::::::::::::::::::-----::-::-::::-::::-:::-- Hut2322 ::::::T:::::::::::::::::::::::::::-----::-::-::::-::::-:::-- rrnAC2691 ::::::T::::::::::::::::::::::::::::::D:RL:YE:ENDD:EYGT:EEL:: Hmu3098 ::::::T:::::::::::::::::::::::::::::::SRL:YE:EAGD:QYGP:ADL:: consensus -RLD--DP--DDFGTLV-ELDG-------VPS----G----Q-V-AVSKH-APDHLV--E #oth 411211224312212113221211113341213333133432313111114222122422 VNG2338 A:::PDTADE::::A::QA:::::::DVF:::VTED:EETL:R:E:::::P:::::LAV: HQ3461A D:::::::EI:AV::::Q:V:DNTDREIS:::IDDN:NERL:S:T:::::R::N:::QI: hla0374 E::N::::QT:::::::N::::::::NVE:::IDEH:NKST:P:T:::::LSQ::::QV: Hbo1434 :---::--::-------:----:::::::---::::-::::-:-:-----:------::- HVO_0065 :---::--::-------:----:::::::---::::-::::-:-:-----:------::- NP0476A :---::--::-------:----:::::::---::::-::::-:-:-----:------::- Hut2322 :---::--::-------:----:::::::---::::-::::-:-:-----:------::- rrnAC2691 S:::::::QE:::::::Q::::::::DLT:S:LGEN::PCR:P:D:::::P::::::EVA Hmu3098 E:::::::RE:::::::E::::::::EVT:::VDAD:RPCRKP:E:::::H::::M:RI: consensus ----R---VTPDH-M-R----G-----A--L--GD--P---------------------- #oth 143213222111131325542233434133243125323122211111111111111111 VNG2338 TKRG:ELT:::::S:R:WTGD:IERVD:RE:TA::AL:APTQV::::::::::::::::: HQ3461A TISG:EITI::::E:HIFEQGNLVSKQ:SKITS:EYAVIPKRLQTISPSSHTPQHDLLRE hla0374 TQRG:SIR:::::T:L:VADG:VQKVA:NE:EI::SV:T::::::::::::::::::::: Hbo1434 ::::-:::-----:-:-::::-:::::-::-::--::-:::::::::::::::::::::: HVO_0065 ::::-:::-----:-:-::::-:::::-::-::--::-:::::::::::::::::::::: NP0476A ::::-:::-----:-:-::::-:::::-::-::--::-:::::::::::::::::::::: Hut2322 ::::-:::-----:-:-::::-:::::-::-::--::-:::::::::::::::::::::: rrnAC2691 :VGD:TLR:::::T:L:AGPD:IEEVP:SD:AA::DL:A::::::::::::::::::::: Hmu3098 :VGD:SLR:::::T:L:RSGD:LEEAP:SE:SA::EL:A::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A FLTRDELTADRLIIHTSDPVRLCNRVFPEEVTSCKDAVEIMQNTACHLDKNKETLIGWLG hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A EGRIPVALLRGFVETDEALLMSIPDDVQIGLRGEKVRIDRHIGFTEELTSLLGYYAAAGI hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A VHTQTNPISYESAQQEQSRITFYNIDTQTQTDLLNALNSVFEIEPIQYNLDGEILGVPGE hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A LIRRVFDTVFDVGTQPSHKRIPQALFDASESHITSYLRCFFSTHDSLTTDTRDISATTVS hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A REFKEDIIAALRRLGITAEVTTQQSRSVPEVLPDWYAIDDITHHDADNSLNLTRSYVISI hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus -----------------------------------------G------D-V--VE-V-SD #oth 111111111111122222222334345444443444533322444113232432232322 VNG2338 :::::::::::::PGDGETATSELRSESLDGTHPQRRFGDG:SVR::T:E:VS::P:R:S HQ3461A ASSDAVTLQRDRQAQEQIKYDAQGLIANNNAIHQSRQVTDG:RKDYITEPITDI:Y:DA: hla0374 :::::::::::::::::::::::TTLRHEMSVGATVDVTTD:GIE::A:T:AS:DFLE:: Hbo1434 :::::::::::::::::::::::::::::::::::::::::-::::::-:-::--:-:-- HVO_0065 :::::::::::::::::::::::::::::::::::::::::-::::::-:-::--:-:-- NP0476A :::::::::::::::::::::::::::::::::::::::::-::::::-:-::--:-:-- Hut2322 :::::::::::::::::::::::::::::::::::::::::-::::::-:-::--:-:-- rrnAC2691 :::::::::::::::::::YDGGETTTMTAR:GEASTAATD:AAP::T:T:EA::Y:E:: Hmu3098 :::::::::::::::::::YDGGETTVMTASDAPQPSAGADDGVP::F:E:VS::Y:D:: consensus --H-Y-LTVA-TH----------QCDGDEDCVMLLMDGLLNFSKTYLPDQRGGR------ #oth 3322131112212323322244311..........1...1...231..11...2111111 VNG2338 VD:T:S::::E:NTLVANGLFTG::::::::::::::::I::::S::::K:::::::::: HQ3461A IDYT:C:::SE::SLIVNDLSQK::::::::::::::::::::RE::::K:::SVAADSR hla0374 IE:T:N::::E::TLAANDLLVA::::::::::::::::::::::F:::::::::::::: Hbo1434 ::-:-:----:--::::::::::--:::::::::::::::::::EF:::K:::Q:::::: HVO_0065 ::-:-:----:--::::::::::--:::::::::::::::::::K::::K:::Q:::::: NP0476A ::-:-:----:--::::::::::--::::::::::L:::::::::F:::::::::::::: Hut2322 ::-:-:----:--::::::::::--::::::::::L:::::::VK:::N::::::::::: rrnAC2691 VD:V:C::::D::RVAVEGTYVG:::::::::::::::::::::S:::N::::Q:::::: Hmu3098 TN:V:C::::D::RVAIEGTYSG::::::::::::::::::::::F::N::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A LVAVSPDDKIVFTTIEDFWKKLNTPIERNGKFRKRTCVSEGWQTYAFDENHEASLRPIEK hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A AIRYTADESEQLRRITTQLGRSLDITDEHSLFRYDDGIEEVAGDDLTAGDIIVAPRTLDV hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A EVTQTTLDLSEYIHDNERCPSEQTGSGELNLASKSAISDSRNKETPGVTHNILPQRSKFT hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A DEMTTLSPTAVGGLESEQNETLRVGESTGAIERYINVDDSFGWLLGQFIAQRSISTDALT hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A MTVHTAAEKHAERIVATSDSVFGIKPTVNSIERGYEIVFPSVFDTIVSGLTAKEQSEPEQ hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A DVDHTHTDEIGIPECILHAPDDIVLSFLQGFILAENAQRKGNAASEASEMVSESETTVTL hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A ETPSVGVKDGLVFLCHRLGVITDISEKSGEEYSVHFEESRYTVSIATEGKTNPLDQILNG hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ------------------------------------------------------------ #oth 111111111111111111111111111111111111111111111111111111111111 VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A ERPTMPEGVSVPVPDALLTIHESIANSPHIDQVIPDTVVQQETVSLETLQSLLTGLSTVD hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus ----------------------------------------------------------MD #oth 1111111111111111111111111111111111111111111111111111111111.. VNG2338 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HQ3461A LPAQLEAKRDELTLLTEGDLSYLRVESVECVDYDGYLYDLQVGGEPVFTANWLYAHNS:: hla0374 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP0476A :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hut2322 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: rrnAC2691 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Hmu3098 :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: consensus APLVMSSRIDPSEIDDEAHNMDIVRQYPREFYEATREMADPEDVEDLITIAEDTLGTDEE #oth ...........1........2..333..21111..11121.3212332211.2111.14. VNG2338 :::::::::::A::::::::I::D:E:::::::::::L::::::A::::L::S:V::::: HQ3461A ::::::::::::::::::::::::::::::::::::R:E::DEW:EEV::::EY:D::N: hla0374 ::::::::::::::::::::V::A:E::::::D::L::::::S:::::Q:G::::::::: Hbo1434 ::::::::::::::::::::::::::::T::::::L:::::GE:::::QLG:::::::D: HVO_0065 :::::::::::::::::::::::::::::::::::LR:E::D:W::EV::::EY::::R: NP0476A :::::::::::A::::::::::::SS:::A:F:::::::::GE::S::QLG::::::AD: Hut2322 :::::::::::A::::::::I:::E:::L:L::::::::H::::D--VK::::::::::: rrnAC2691 :::::::::::::::::::::::MDA::::::::::::K::TE:::VMK:::E:::::R: Hmu3098 :::::::::::::::::::::::M:E::::::::::::::::::::VM::::E:::::H: consensus YTGFDHTHDTTDIAAGPDLSAYKTLGSMMDKMDAQLELARKLRAVDETDVAERVIEYHFL #oth .21.5...1.31112..1.......11.21......211.1..1.2.1.....1...... VNG2338 ::::G:::A:SN:HL::S:::::::::::::::::::::::::S:A:::::::::::::: HQ3461A ::::N::::::::::::::::::::D:::::::::::::::::::::::::::::::::: hla0374 :H::G:::::::::M:::::::::::D::E:::::::::::::::::::::::::::::: Hbo1434 :R::::::::S:::L::::::::::::::::::::::::::::::::::::::::::::: HVO_0065 ::::::::::::::::::::::::::::::::::::F::::::::::::::::::::::: NP0476A :R::E:::::V:L:::::::::::::D::E::::::::S::::S:::::::::::::::: Hut2322 ::::A:::::SN::L:::::::::::::E::::::::IS::::::::::::::I:::::: rrnAC2691 ::E:R:::::AN::::::::::::::::E::::::::IS::::::V:S:::::I:::::: Hmu3098 ::::::::::::::L:::::::::::::T:::::::D:S:T::::::::::::I:::::: consensus PDLIGNLRAFSRQETRCLDCGEKYRRMPLTGDCRECGGRVNLTVHEGSVNKYIDTAIRVA #oth ..1..........31...1...11..2..1.2......1......1...1..2...241. VNG2338 :::::::::::::::::::::::::::::S::::::::::::::::::::::M:::M::: HQ3461A :::::::::::::Q::::::::S::::::::E::::::::::::::::::::M::::HI: hla0374 ::I::::::::::K:::::::::::::::S:::::::::::::::::::S::V::::E:: Hbo1434 :::::::::::::::::::::::::::::::::::::::::::::Q::::::M::::Q:: HVO_0065 :::::::::::::::::::::::::::::S:::::::::::::::Q::::::M::::Q:: NP0476A ::I:::::::::::::::::::::::V::::::::::::::::::Q:::::::::::Q:: Hut2322 :::::::::::::DV:::G::::::::::::T::::::D:::::::::::::::::T::: rrnAC2691 ::::::::::::::V:::::::SF::A::::::::::::::::::::::::::::::::: Hmu3098 ::::::::::::::V:::::::::::::::::::::::::::::::::::::::::TM:: consensus EEFDCREYTKQRLEILDRSLESVFEDDTNKQSGIADFM #oth 21111.2......2111232111..1.21111112... VNG2338 T:Y::::::::::::M::R:::::::::::::::S::: HQ3461A ::::::::::::::V:E:::::I::::::::::::::: hla0374 DR:G::P::::::KV::Q::::I::::::::::::::: Hbo1434 ::::::P:::::::V:EK:::::::N:K::A:KLG::: HVO_0065 ::::::D:::::::V:EK:::::::N:K:::::::::: NP0476A ::YG:::::::::R::::AV::I::::::::::::::: Hut2322 :::GA:::::::::::::AIKR::::::SR:T::G::: rrnAC2691 D::GA:D::::::K::E:KI:::::N:H:::::::::: Hmu3098 :::::::::::::::::K:IKR:::N:K::::::::::