[E] (GLY1) COG2008 Threonine aldolase 5 genomes BUD1675 5 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2447 - HVO_0243 Hbo1254 Hmu1813 - hla1966 - -

Pairwise sequence scores
Consensus score	2556	VNG2447	hla1966	Hmu1813	HVO_0243	Hbo1254
1483	VNG2447	2667	1258	1133	1108	1193
1943	hla1966	1258	2596	1586	1590	1604
1920	Hmu1813	1133	1586	2467	1555	1608
1986	HVO_0243	1108	1590	1555	2543	1778
2050	Hbo1254	1193	1604	1608	1778	2595

367 symbols
consensus       ------------------DMIDLRSDTVTTPSEAMREAARDAPVGDDVYGDDPTVNELEA
#oth            1111111111111222222311111111231222.....12.2.1111111..1.111.1
VNG2447         MFRNVTGRMTFPPGGGCP::::::::::A::T:::::::AQ:::EHGEH::::A:AAV::
hla1966         :::::::::::::MEIDE:T::::::::::::::::::::::E::::::R:::::::::R
Hmu1813         ::::::::::::::::::----------------::::::N:::::::::E::::A::::
HVO_0243        ::::::::::::::::::-::::::::::L::DE::::::::A:::::::::::::::::
Hbo1254         ::::::::::::::::::MS:::::::::R::::::::::::::::::::::::::::::

consensus       RAADLVGKEAALFVPSGTMGNQIAARVHTDRGQELLVDRESHIYRWELGGLAQLSGLQVR
#oth            2..211.211.11..11..1...1121.121..13.11131.2.21121.3111112.3.
VNG2447         T:::A::MA::V::::R::A:::G:Q:::A:::SV::E:A::S::RGS:::::HA:V:A:
hla1966         ::::A::T::::Y::::::A::::VH:::EP:::::LE::::::::::A:ASK:::T:T:
Hmu1813         :::G:L::AD::::::::::::::V:A::E::::::L:::::::::::::T::HAQV:C:
HVO_0243        :::E::::::::::::::::::::::::A:P:::A:::EKA:V:E::V::F:::::::::
Hbo1254         A::E:::M::::Y::T::::::::::::::::::I:::EQA:::K:::::::::::::::

consensus       TVDAGERAVPTPEQVRDGAVEEDLHRPGTGLLCLENTHNARGGVAVPVAAIDAAADAAHD
#oth            131111222..1211323421221.2111.1231.11.111..112134422..212.12
VNG2447         AF:G::TGC::A:::AAEITAGGG:::EV::A:V:IA:G:N:::VA::D:FA::VET::E
hla1966         :I:::D:C:::::S::E:L:::::::::::::S::::::Y:::T:I::NQ:T:::EV:R:
Hmu1813         ::::S::C::::::ISEAF:A::::::::::VT::::::Y:::::::ESHV:::C::::A
HVO_0243        AY::::::A:::A::::H:R::S::VA:::V::::::::::::::::K:D::::::::R:
Hbo1254         ::A::DA:::::Q:IQ::Y::QS::EA::::VAV::::::::::::SPET:::::::::E

consensus       LGVPVHLDGARLFNAAVALDVDPAALVRPVDSVMFCLSKGLGAPVGSILAGSEAFVEEAR
#oth            211...1..1.111.11..12112323331.1.23...1.....1.121..3121123.1
VNG2447         HD::::V::T:V:S::T::G::A:T:LS:::::AV:::T:::::M:AV:::::S::AS::
hla1966         AD:::::::::V:::::::G::ASEI:A:::T:T::::::::::::::V::D:::::D::
Hmu1813         ::::::::::::W:::::::TA::::A:EA::::A::::::::::::V:::T:S::D:::
HVO_0243        ::I::::::::::::C::::E::T:M:ER::T::C::::::::::::M:::P:::I:::V
Hbo1254         :::::::::::::::C::::::::RMT:A:::::::::::::::::::::::SEY::R::

consensus       RVRKLFGGGMRQAGMIAAPGLRALDNVDRLADDHENARRLAEGLDAIDGLSAPEPDTNIV
#oth            .11121....1...21..1.14..1.12.121..1..31..21..122.23111.1....
VNG2447         ::QEMY::::Q::::V::A:VC::E:RH:VHE::::::::::D:::LP:VT:A:::::::
hla1966         :::::::::::::::::::::L::E:::::V:::A::E:::T::::L::IH:::::::::
Hmu1813         :L:::::::::::::::::::E:::::::::::::::::::T::::::::RV:T:E::::
HVO_0243        ::::Q:::::::::L::::::V::::::::::::A::TV:::::::VS:::V:T::::::
Hbo1254         ::::::::::::::I::::::::::::E:::::::::A:::A:::D::::::::::::::

consensus       VVDSEDAGITAAAFVEGCEDAGVLGGAFGEYTTRFCTHLDVDRADVDAAVDRIGDVVEAA
#oth            212123.1211431123.323..2123322121.11.1111211.122112222311344
VNG2447         LA:TR::DV:::::LA:::EE::::T:D::::V:::::R:IGG::IA:V:SAA:E::---
hla1966         :AHT:::::::SDL:TA:K::::GCVE:A::::::T::::::GD:I:::I::::::IAEL
Hmu1813         :::::P::::SD::::::VAR::RC:SVS:::::L::N:::::::::::I::::R::R::
HVO_0243        :::::G::L::EE:::L:D:V:::::T::Q:H:::T:N:N:S::::ER:::LVA:A::SR
Hbo1254         Q:F:DE::LS:TS:::R::::::::::H:DHL:::::::::S:::::D::E::EAAI:GS

consensus       -------
#oth            3211111
VNG2447         :::::::
hla1966         A::::::
Hmu1813         TE:::::
HVO_0243        :::::::
Hbo1254         SQTSGSR