[R] (-) COG2047 Uncharacterized protein (ATP-grasp superfamily) 9 genomes BUD0717 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0546 rrnAC3510 HVO_0697 Hbo0838 Hmu0980 Hut0447 hla2326 NP1624A HQ1257A

Pairwise sequence scores
Consensus score	1871	VNG0546	HVO_0697	Hbo0838	HQ1257A	NP1624A	hla2326	rrnAC3510	Hut0447	Hmu0980
1326	VNG0546	1853	1077	1089	1146	1150	1253	1177	1151	1215
1452	HVO_0697	1077	1882	1374	1391	1120	1310	1282	1227	1284
1443	Hbo0838	1089	1374	1872	1406	1242	1300	1278	1220	1270
1449	HQ1257A	1146	1391	1406	1879	1163	1282	1237	1226	1312
1401	NP1624A	1150	1120	1242	1163	1875	1230	1314	1252	1331
1478	hla2326	1253	1310	1300	1282	1230	1874	1346	1260	1313
1589	rrnAC3510	1177	1282	1278	1237	1314	1346	1889	1488	1532
1513	Hut0447	1151	1227	1220	1226	1252	1260	1488	1873	1475
1594	Hmu0980	1215	1284	1270	1312	1331	1313	1532	1475	1862

256 symbols
consensus       MDEIEIERVADPDLDDPVLVEGLPGVGHVGKLAAEHLLEELD-SELVRRVYSDHFPPQVT
#oth            .113221532233.32.1.1.......1....11..121.21122213111133.....1
VNG0546         :::LS::W::E:S::::A::::::::::::::V:::VIA:A::::::C::H:EY::::::
HVO_0697        ::D::::A:EEV::T::::I:::::::N:::::V::::::FEEAT::::::A:A:::::S
Hbo0838         :ED::V:TL:::::R::::::::::::::::::V:::::::::::P::YI:A:E::::::
HQ1257A         :ED::::T:GEAT:R::::::::::::::::::V:::V::F::::ELT:::A:E::::::
NP1624A         :::FD:::P:::E::N:::I::::::::::::::::::::F::A:::::I::E:::::::
hla2326         ::D:::DE::T:E::::::I::::::::::::::::::::F::G::::::::TE:::::S
rrnAC3510       :::FD::::::::::E:::::::::::::::::::::::::E::::::::::T::::::S
Hut0447         :::Y:T:VL::V::EE::::::::::::::::::::::::::::TP::::::Q::::::S
Hmu0980         :::F::::I::GE:T:::::::::::::::::::::::::::::V::A::::Q:::::::

consensus       V-DDGVAELACAEFHAVE-P-DGRDLLVLTGDHQAQDNAGHYGLTDTFLDIAEEFGVERV
#oth            23211421.141321.14122323.2.211.....2335.1.31121...2122112334
VNG0546         :G::S:::::A::I:::::T:G::::::V::::::::TV:Q:RV:EA:::A:A::DATD:
HVO_0697        I::E:::::THVAI::::T:GE:P:::L::::::::S:E:::H::::::::G:::::::L
Hbo0838         LN::S::Q::R::::::D:A:GD:::::::::::::T:S:::H:::A:::::::::::EG
HQ1257A         :D::::T:::H:S::::S:T:::P:::I::::::::SH::::H::::::::::DM:A:S:
NP1624A         ::E::RTQ:::::VY:IS:A:AE::C:::::::::A:GP:::R::EA:::V:AA:D:S:I
hla2326         IDG::::::T:::::::::T:::A:::::::::::GS:::::K::T::::::::::AT:A
rrnAC3510       I::E:Q:Q:::::::::T::EE:Q:::::S::::::N:Q:::::::::::::D:::IQ::
Hut0447         ::E::I-:::S:T::::T::E::Q:M:::S::::::::V:::::VE::::V:AD:D:::I
Hmu0980         ::E::TTQ::S::::::R::E::::M::::::::::::E:::::::::::V:::::::S:

consensus       FALGGVPTGELVEEPDVLGAVTTEDLIEELEDAGVEFRENEPAGGIVGVSGLLLGLGGRR
#oth            21.........11222.1..322434424.332112..23.....1..1...11.1131.
VNG0546         :S:::::::::::DH::I:::SSAA:KDG:A:::::::SE::::::::S::::V::::K:
HVO_0697        ::::::::::::D::S:::::AD:SRLD::DE::I::::G:::::V::::::::::::::
Hbo0838         Y:::::::::::D::S::::::D::DV:R::AVD:::::D:::::::::::::::::E::
HQ1257A         Y::::::::::::::::::::A:NGG:DP:S::::::::G::::::::::::::::::::
NP1624A         :::::::::::::T:::I::A::D:::::::AVD:::::::::::::::::::::::E::
hla2326         ::::::::::::::YT:::::SDG::::G:::V:::::PD::::::::::::V:::::::
rrnAC3510       :::::::::::I::Y:::::T::::FK:T::ES::A:::D::::::::::::::::SK::
Hut0447         V::::::::::I::Y::I::::::::ET:::::::D:::::::::::::::::::M:Q::
Hmu0980         Y::::::::::I::Y:::::S::DS:V::::SV::A::::::::::::::::::::S:::

consensus       GLDAACLMGETSGYLVDPKSAQAVLEVLQDLLGFEVDYESLEERAEEMEEVVRKIQEME-
#oth            24312.............21.21.112.334231221231.11..11.1..1521.2.13
VNG0546         :F:::::::::::::::::A:K:::A::GAR:D::M:E:A:DD:::::::::SRL:D:::
HVO_0697        ::::T:::::::::::::Q:::V:I:::::::Q:S::F::::::::::K::AA:::::QQ
Hbo0838         ::SV::::::::::::::Q:::V:::::::VID:::GF::::::::::K:::G:::::QS
HQ1257A         ::S:::::::::::::::T:::::::::ETVV::::G:::::::::::K:::E:::Q:QG
NP1624A         :YE::::::::::::::::::RV:::A:EETVPLDIG:D::::::D::::::KQ::Q::Q
hla2326         :F:::::::::::::::::::R::::::A:H:D:SI::::::D:::::::::G:::::Q:
rrnAC3510       DVP:S:::::::::::::::::::::I:::VI::::::S:::D::D:::::::::::::Q
Hut0447         EWP:::::::::::::::::::::::I:::::::::::A::::::DD:::::::::::::
Hmu0980         D:::::::::::::::::::::::::I::E:::::I:::A::D::D:::::A::::::::

consensus       QQQPS-PSDEDLRYIG
#oth            2542314511......
VNG0546         -ET::::G::::::::
HVO_0697        :::G:IA::D::::::
Hbo0838         :::GM:-N:D::::::
HQ1257A         :::GM::T:D::::::
NP1624A         NATAA:::E:::::::
hla2326         -DG:A:VP:D::::::
rrnAC3510       :NS::::A::::::::
Hut0447         :GA:::SP::::::::
Hmu0980         :GT:T:::::::::::