[S] (-) COG2098 Uncharacterized protein conserved in archaea 9 genomes BUD0769 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0127 rrnAC2306 HVO_0510 Hbo1041 Hmu0082 Hut2533 hla0456 NP0408A HQ1136A

Pairwise sequence scores
Consensus score	869	Hut2533	HQ1136A	NP0408A	VNG0127	Hmu0082	rrnAC2306	hla0456	HVO_0510	Hbo1041
567	Hut2533	875	456	428	509	488	488	470	459	494
596	HQ1136A	456	932	532	493	528	548	539	554	559
606	NP0408A	428	532	879	510	597	602	468	502	494
601	VNG0127	509	493	510	831	469	507	576	511	552
661	Hmu0082	488	528	597	469	898	624	510	594	568
678	rrnAC2306	488	548	602	507	624	861	545	575	622
642	hla0456	470	539	468	576	510	545	877	588	562
655	HVO_0510	459	554	502	511	594	575	588	855	620
676	Hbo1041	494	559	494	552	568	622	562	620	855

124 symbols
consensus       ---MMPTDAQEACFEAGIKFGSLYHQFAGTPVSPASADSLAAAMEEAIENQPHCEAVTVD
#oth            111243.2125.1..1.1...2.........11.2.142.14.1121.2...2.14.3.5
Hut2533         ::::E::::HR:T::L:::::A:::::::::I:::::AE::S:I:S:::::::::E:S:G
HQ1136A         MQTTAA:T:E:::::::::::T:::::::::::::::ST:ED:IAD:::::::::::S:T
NP0408A         ::::K::TP::::::::::::T::::::::::A:E:S::::::::D::::::F:T:::::
VNG0127         :::-:A::::Q::::::::::A:::::::::::::::P::ET:I::S:R:::F::G:A::
Hmu0082         ::::D:::P:V::::::V:::::::::::::I::D:::::::::A::::::::::D:::E
rrnAC2306       ::::E::AP::::::::V:::::::::::::I::D:::::::::::::::::F::::::S
hla0456         :::-:T::::Q::::::::::::::::::::::::::R::E:::A:::::::F::S:::E
HVO_0510        :::-:V::P:T::::::::::T::::::::::::D::R::ER::A::::::::::S:S:H
Hbo1041         :::-::::::N:::::::::::::::::::::::E::::::R:I::S:A:::Y::::R:T

consensus       IRDDALEAALADQSADYTELTGRFMDVEMQIDYEGVTVRTSMAMDDGYPLMRLVSVDA--
#oth            2341324533226432...1..3241.12612.2.431325.3.211..1.422412634
Hut2533         MKTE:I:T:V-:PDVG:::F::E:A:::ILV::::LEA:GV:E::::::R::::GI:DTA
HQ1136A         V:T:R::T:::E:::E::::::K:F::T:::E:N:CR:Q:Q:T::GD::::EI:A:ESPT
NP0408A         :L:EK:RKT::E::::::::::EY:E::LI:E:D:C::AA:::::GD::R:QVDD::G::
VNG0127         :KTER:-----:VEHG::::::EY::::LR:::::T::AAE::::::::::::AEI:P::
Hmu0082         ::E:::R:EIE::::::::F::::AE:::TV:::::A:E:::R::GD::::AVDD:::PE
rrnAC2306       V:ME:::S:I:EGG::::::::::I::::::E::::::E:::::E::::::QVDA:QE::
hla0456         :H::RVAD:I-:HENG::::::SL:::::::A:::IE:::R:::R::::::E::::E:AK
HVO_0510        :L::::D:E::GST:::::::::::E:::E::::::R:::E:E:E::::::KI:::E-::
Hbo1041         ::R:E:::::E:AT::::::::::L::::D:E:::TA:Q:K:E:E::::::K::::EE::

consensus       ----
#oth            2111
Hut2533         ::::
HQ1136A         DDSS
NP0408A         ::::
VNG0127         ::::
Hmu0082         ::::
rrnAC2306       ::::
hla0456         SD::
HVO_0510        ::::
Hbo1041         ::::