[H] (CobL) COG2242 Precorrin-6B methylase 2 8 genomes BUD0990 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1550 rrnAC2998 HVO_B0062 Hbo1627 Hmu1991 - hla2064 NP1124A HQ1834A

Pairwise sequence scores
Consensus score	1366	HQ1834A	NP1124A	HVO_B0062	Hbo1627	VNG1550	hla2064	rrnAC2998	Hmu1991
952	HQ1834A	1365	856	1016	983	817	865	858	894
988	NP1124A	856	1313	922	879	946	918	956	943
1134	HVO_B0062	1016	922	1367	1157	935	980	1010	1005
1132	Hbo1627	983	879	1157	1364	885	1025	988	970
1095	VNG1550	817	946	935	885	1370	1006	1071	1049
1144	hla2064	865	918	980	1025	1006	1564	1118	1096
1186	rrnAC2998	858	956	1010	988	1071	1118	1469	1120
1156	Hmu1991	894	943	1005	970	1049	1096	1120	1367

211 symbols
consensus       MSRVSLPHDAKAGPTKPEVRAVTLDKLALTPDDHFVEVGSCTGAVTIEAARRAGRVTALE
#oth            .2323.....1.....1...11243..4.423...11..2...111.4.123132...2.
HQ1834A         :TQIT:::::R::::::::::I:IQ::Q:Q::::::D::T::::IS::::PYVTH:::I:
NP1124A         :T:TA:::::::::::::::S:::G::N:::E:::A:::A:::::::::::Q::T:::V:
HVO_B0062       ::Q:T::::::::::::::::::::::G:R:T::::D::::::S::::::::VE::::V:
Hbo1627         ::::T:::::::::::S::::::::::D:R:T::::D::::::S:S::::Q:VK::::V:
VNG1550         :AQTQ:::::::::::::::::VRS:::::D::::::::::::::::A:::D::::::::
hla2064         ::N:::::::::::::S:::::LQG::D:A:::::::::::::::::D::::::::::::
rrnAC2998       ::::::::::::::::::::::LAS:::::GS:::A:::::::::::T::::::::::::
Hmu1991         :AH:::::::::::::::::::L::::::G:::::A:::::::::::Q:S::::::::::

consensus       RKADRLEVTRKNLAANDYDADVTLREAEAPAGLPDDADALFLGGSRNYEAVLDHAVETGV
#oth            ..46123212..11..36422.41221...31..41..11.2.....1211..1122321
HQ1834A         ::SQ:VTAAK::I:::NQTET:SVE:::::N:::RN::V::::::::F:S::::::::D:
NP1124A         ::ET:I:TAA:::D::GI-E::D::Q::::N:::T:::::::::::::G::::F:A:N:I
HVO_B0062       ::P:::D:::::::::::::::::::::::D:::T::::M:V:::::F::::::::::::
Hbo1627         :::K::::::::::::E:::::A:H::::::::::::::M:I:::::F::::::::KSEI
VNG1550         :::::::T::::::::GLADA:E::N:::::E::A::::::I::::::D::::::A::::
hla2064         ::PE::A::::::::::TS:::::::T:::::::E:::::::::::::::I:::VGAHD:
rrnAC2998       ::GN::D::::::::::V::::E:::::::E:::::::V:::::::::::I:::::::::
Hmu1991         :::SKVAT:::::::::AA::::V::::::D:::::::::::::::::::I:::::::E:

consensus       DRIVMNVSRLEVAGAATEAFRERDLLDEVVQFQVSHGYELAGATSFDSNNPVYMLVGRA-
#oth            ..1......1.11.2.22...1.21131.2.3..12..........413....22..222
HQ1834A         ::V::::::V:P::D:I::::::E::SA:L:V::ND::::::::::NA:::::VI:::R:
NP1124A         ::::::::::::::D:VR:::::::FE::I:L:::T::::::::::E:D::::VI::G:Q
HVO_B0062       :::::::::V:P::D:I::::::G::SA:::L::::::::::::::R::::::VV:::R:
Hbo1627         ::V::::::V:PT:::I::::::::::::::M::::::::::::::K::::::II:::R:
VNG1550         :::::::::::::::::Q:::D::I:T:::::::::::::::::::::E::::::::S::
hla2064         ::V:::::::::::::::::::::::::::::::::::::::::::::Q::::::::GTE
rrnAC2998       ::::::::::::::::::::::::I:E:::::::::::::::::::N:E::::::::S::
Hmu1991         ::::::::::::::S::::::::EI::::::::::::::::::::::AE::::::::G::

consensus       ------------------------DAGGLR-
#oth            1111111122111211122222333422441
HQ1834A         :::::::::::::::::::::::::::::T:
NP1124A         ::::::::::::::::::::::::------:
HVO_B0062       ::::::::::::::::::::::::::E::-:
Hbo1627         :::::::::::::::::::::::::::::D:
VNG1550         ::::::::::::::::::::::SG:TEAD::
hla2064         ATANDLHVDDDVATDGGRANASRL::::DDR
rrnAC2998       ::::::::SEDVAADGGSPTETEATD::Q::
Hmu1991         :::::::::::::::::::::::GNRE:EQ: