[L] (-) COG3436 Transposase and inactivated derivatives 1 genomes BUD4420 6 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0021 VNG0056 VNG5087 VNG5210 VNG6084 VNG6442 - - - - - - - -

Pairwise sequence scores
Consensus score	3562	VNG0021	VNG5087	VNG5210	VNG6084	VNG6442	VNG0056
3562	VNG0021	3562	3562	3562	3562	3562	3141
3562	VNG5087	3562	3562	3562	3562	3562	3141
3562	VNG5210	3562	3562	3562	3562	3562	3141
3562	VNG6084	3562	3562	3562	3562	3562	3141
3562	VNG6442	3562	3562	3562	3562	3562	3141
3141	VNG0056	3141	3141	3141	3141	3141	3696

468 symbols
consensus       MEERIDELEEKLEQKD--------------ERIEELETRLRKYENPHTPPSKRRSGTDES
#oth            ...........11...11111111111111..............................
VNG0021         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5087         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5210         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6442         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0056         :::::::::::IA:::KRIEEQNERIEEQQ::::::::::::::::::::::::::::::

consensus       PTSQDDEDDDVRTDGGTPGRKDGHDPEWRSTTDPDEEIEVTCDCCPECGDHFDESVGVSP
#oth            ........................1.....11.........1..................
VNG0021         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5087         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5210         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6442         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0056         ::::::::::::::::::::::::N:::::PP:::::::::S::::::::::::::::::

consensus       RLVEEIPDPQPPEITRYNRHYYQCDSCGTETVAAHPDCPDEGQFGVNVIAQSALSRYDHR
#oth            .....1.......1.1....1............1..........................
VNG0021         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5087         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5210         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6442         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0056         :::::V:::::::V:Q::::R::::::::::::T::::::::::::::::::::::::::

consensus       LPYRKIADRFEQLHELELSGASAWHATERAARAGRCEYEQIRREIQDADVVHIDETGIKR
#oth            ......1.......1...............................1.11..1.......
VNG0021         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5087         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5210         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6442         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0056         ::::::T:::::::G:::::::::::::::::::::::::::::::E:EI::V:::::::

consensus       DGEQAWIWTFKTAQHTLYAVRESRGSDVPAEVLGEDFAGTVICDGWTAYPAFSSNLQRCW
#oth            ..1.......1.11........................................1.....
VNG0021         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5087         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5210         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6442         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0056         ::D:::::::R:DE::::::::::::::::::::::::::::::::::::::::T:::::

consensus       AHILREAEDAAEKQAEGEPIYHALRQVYVALQARLESDPSPRERADLQRVARRELESLIE
#oth            ..1......1.1111.1..1.11.1.11.1..11..1..1..1..111.11111.1..1.
VNG0021         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5087         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5210         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6442         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0056         ::L::::::V:SDHE:A::V:RY:K:MF:G::SW::T::D::A::QMH:ACQDG:R::V:

consensus       RSVPDGPVATLLGKIEGGLDHWLTFVGEPAVSPTNNAAENALREPVVLRKIIGTLRNDRG
#oth            ...1.1......................................................
VNG0021         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5087         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG5210         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6084         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6442         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0056         :::T:E::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       MFVHETVLSLLATWRQQGRNPYEELRRVVSSNEMLSRAHAVPAVETSG
#oth            ......1..................1...11...1..111..1.....
VNG0021         ::::::::::::::::::::::::::::::::::::::::::::::::
VNG5087         ::::::::::::::::::::::::::::::::::::::::::::::::
VNG5210         ::::::::::::::::::::::::::::::::::::::::::::::::
VNG6084         ::::::::::::::::::::::::::::::::::::::::::::::::
VNG6442         ::::::::::::::::::::::::::::::::::::::::::::::::
VNG0056         ::::::I::::::::::::::::::T:::HD:::I::EQT::V:::::