[E] (PotA) COG3842 ABC-type spermidine/putrescine transport systems, ATPase components 9 genomes BUD0343 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0921 rrnAC0908 HVO_1707 Hbo3129 Hmu1588 Hut2580 hla0066 NP3648A HQ2543A

Pairwise sequence scores
Consensus score	2802	Hut2580	NP3648A	HVO_1707	Hbo3129	HQ2543A	hla0066	VNG0921	rrnAC0908	Hmu1588
1912	Hut2580	2842	1638	1625	1636	1564	1685	1669	1591	1654
1992	NP3648A	1638	2904	1777	1907	1787	1682	1632	1660	1582
1998	HVO_1707	1625	1777	2940	2146	1952	1539	1632	1609	1647
2149	Hbo3129	1636	1907	2146	2833	2187	1676	1722	1623	1634
1996	HQ2543A	1564	1787	1952	2187	3308	1659	1606	1531	1588
2019	hla0066	1685	1682	1539	1676	1659	2920	1803	1773	1792
2066	VNG0921	1669	1632	1632	1722	1606	1803	2800	1847	1871
2022	rrnAC0908	1591	1660	1609	1623	1531	1773	1847	2820	2228
2101	Hmu1588	1654	1582	1647	1634	1588	1792	1871	2228	2821

463 symbols
consensus       M-----SKPDQ---DTRRSTA----------DSATAAPSDTVLELDGVTKEYGAETAVDD
#oth            24434345465111553543432232111116446447554.11.212314114131143
Hut2580         VTASQH:T:VD:::AQP:::G::::::::::A:EP:EKGRA::::::::RQF::::::AN
NP3648A         -:::::-MSSE:::LK:TDQSA:::::::::GP:A::AGQ::::::D:Q:S:DGMDVIR:
HVO_1707        :SNSTL:TT:R:::SN:AEATD:::::::::SETDD:DAGG:::::::S:S::T:SVI::
Hbo3129         :N::::-----::::QSA:AS::::::::::::E:RSE:EA::::::LK:S::T::VIH:
HQ2543A         -::MNS::TT::::E::::P-::::::::::V:DESNHT:E::::CDLQ:H::T::V::H
hla0066         :AHTQSV::T:SAG:ASE:P:EANESHAGATE:::D:SP:P::S:S:::::F:P:::::G
VNG0921         :AESASRRHAD:::::S::::EF::::::::-----SG::::::::::::::::::::R:
rrnAC0908       -:::::-MSR::::TRTQQ:SDFDDV::::::A:V:N:NR::::::D:S:D::H:V::EN
Hmu1588         -:::::ME::I::::::NT::AFDSV:::::E::VDD::A::V::::I:R::::::::::

consensus       LSLSVRDGELLTLLGPSGCGKTTTLRLIAGLERPDGGAIRLNGEVVAGGSTFVPPEERDV
#oth            11.3.43..1..1.............21...12124.51424455121533.121.3.31
Hut2580         :D:T:Q:::::::::::::::::::::L:::DE::A::::VA::T:::EG:::K::N:::
NP3648A         :::D:::::::::::::::::::::::::::::::N:TV::GSTP:S:SE-:::::Q:::
HVO_1707        :::::EE::I:::::::::::::::::::::D:::::EV::::N::S::D::RA::::G:
Hbo3129         ::::::E::I:::::::::::::::::L::::::::::V::::R::S:TE-:::::::G:
HQ2543A         :::::NS::I::::::::::::::::::::::AV:::IV::::KN:T:S:-:::::Q:G:
hla0066         V::D:NP:::::F:::::::::::::T:::::E:TE:Q:T:GD:T:S:DGA:::::Q:::
VNG0921         ::::::E:::::::::::::::::::ML::::::T::T:E:DAQR:::PD:::AA:D:EI
rrnAC0908       :::G:K::::::::::::::::::::M:::::::SD:Q:SIAD::I:D::S:RK::::N:
Hmu1588         :::::N::::::::::::::::::::M:::::::S::S:QIEERA::D::::RK::::N:

consensus       GIVFQEFALFPHLTVAENIAFGLTDRSEDETDERVDELLELVDLPDHGDKSPDELSGGQQ
#oth            .2...21......212..1...15163331534..211.2..115433133123.....2
Hut2580         :L:::::::::::::G::V:::IQ:::D::I:Q::TD:::::G:D:YREA::ED:::::R
NP3648A         :V:::::::::::SAR::::::IQEW::A:QQ::::::::::G:V:::::::E:::::::
HVO_1707        :V::::::::::::A::::::::K:L::S:R::::AD::D::G:ETQ::SY:::::::::
Hbo3129         :V::::::::::::AR:::::::A:::DA::EQ::::::::::::RQ::SY:::::::::
HQ2543A         :V::::::::::::AR::V::::::H:SA:::H:::::::::::::QSESY:::::::::
hla0066         :::::N:::::::::R:::::::G:-GA:A:AD::::M:D:::::E::E:T::Q:::::K
VNG0921         :::::D:::::::S::::V:::::::D::A:AA::::M:A:::M:EM::R:V:Q::::::
rrnAC0908       :::::DY:::::::::::::::::EME::AVA::::::::::::SA:H::M:SQ::::::
Hmu1588         :::::DY::::::N:::::::::R:ADSR:A::::T::::::::T::RE:M:SK::::::

consensus       QRVALARSLAPEPDILLLDEPFSNLDVRLRVEMREEVRRILKEAGVTAISVTHDQEEALS
#oth            ....1........22............2..12..1...3.1.21....1.........1.
Hut2580         ::::::::::::::V::::::::::::G::E:::R:::::I::T::::V:::::::::::
NP3648A         :::::::::::::KL::::::::::::D::::::::::D:::::::::::::::::::M:
HVO_1707        :::::::::::::A:::::::::::::D:::Q::::::::::::::::V:::::::::M:
Hbo3129         :::::::::::::::::::::::::::D:::Q::::::::::::::::::::::::::::
HQ2543A         :::::::::::::::::::::::::::D:::A::::::::::::::::::::::::::::
hla0066         ::::::::::::::V:::::::::::::::::::::::Q:::A:::::V:::::::::::
VNG0921         ::::V:::::::::::::::::::::::::::::::::::::::::::V:::::::::::
rrnAC0908       ::::::::::::::V:::::::::::::::::::::::K:::R:::::::::::::::::
Hmu1588         ::::::::::::::V:::::::::::::::::::::::K:::R:::::::::::::::::

consensus       ISDRVAVMNDGRIEQVGDPEEVFQHPESRFVASFLGQASFLSGRVAGDRVETGLGTFDRE
#oth            ......1222.621.1.4.15..13.1.1...2...3.2.22133541612.43.43343
Hut2580         :::::::VR:::V::I:R::I:::Q:::::::E:::::G:V::TF:EGC:D:P::CL:AD
NP3648A         :::::::::N:::::::T::G:::Q:K:::::G:::H:::V::Y:EDGC::::V:CVPL:
HVO_1707        :::::::::::DL::::E::Q:::::::::::G:::Y:G::P::I:::A:::E:::V::D
Hbo3129         :::::::::::NL::::E::S:::::K:::::G:::Y:::IP:Y:S::::::D::NLP::
HQ2543A         ::::::::S::H:::::K::A:::::::::::::::Y:::IP:Y:S::V:Q:EV::VP::
hla0066         :::::::::E:Q:::::R::S::ER:::K:::::::R::::E:HLRDGK::::I:R::AV
VNG0921         :::::::L:::C::::::::G::E::::::::::::::A:::A::GS:T:D:AV:SY::A
rrnAC0908       ::::::I::::T:A:I:::A:::EN:::::::::::::::::A::TN::I:::::S:NV:
Hmu1588         ::::::I::::T:::::::A:::EN:::::::::::::::::A:::::DI:::M:::RTA

consensus       QINGLADEYDGARVDVLVRPDDLRARPAAP------------------------------
#oth            323.2353.33251.21.....23172444311111111111111111111111111111
Hut2580         R:E::DT::E::D:::::::::I::V::D:::::::::::::::::::::::::::::::
NP3648A         :V:::T:V:::SEI:LM:::::VC::::S:::::::::::::::::::::::::::::::
HVO_1707        ::H:::P:::DTDI:I::::::VS:H:CDG::::::::::::::::::::::::::::::
Hbo3129         ::H:::A:::NT:I::::::::VS::ACE:G:::::::::::::::::::::::::::::
HQ2543A         ::H:::S::NQT:I:L::::::VSVCQSN:DRNDRQTRDHGNMTADGAGAHAQFTNTTKT
hla0066         TLE:YDTV:::TP::::::::::::S::SA::::::::::::::::::::::::::::::
VNG0921         LLA::T:G:Q::M::::::::::::A:V:DA:::::::::::::::::::::::::::::
rrnAC0908       LL::PVEA:N::M::::::::::Q:M:TNE::::::::::::::::::::::::::::::
Hmu1588         RL::PVEA:N::T::::::::::::I:T:E::::::::::::::::::::::::::::::

consensus       -------------------EEANGRVVARQYLGPSFLYRVELESGDVVHCMHNHAEEFPL
#oth            11111111111111111123734.411611.3..122.3.1123.2414.2...314456
Hut2580         :::::::::::::::::::AGT:::I:D:::T::::V:T:::D::AIL::E::::::LGM
NP3648A         ::::::::::::::::::::::::E::H:R::::TV:::::I::::::G::::::D:VS:
HVO_1707        :::::::::::::::::::GDGH:K::GKR::::TI::E:::HG::TLL:::::D:TV:T
Hbo3129         :::::::::::::::::::::PS::::::R::::T:::E::::T:ER:Q:::::D:DV:D
HQ2543A         TSSPISGTTADEYADTQIN:YGC:E::::R::::T:::E::::T:ES:Q:::::D:DI:E
hla0066         ::::::::::::::::::::L:D:TI:S:::V::::I:::::::::::::L:::V:::D:
VNG0921         ::::::::::::::::::TGAG::TI:K:::T::::I:H:::DN::::R:L::::DNMAI
rrnAC0908       :::::::::::::::::::SK:D:Y::H:::N::::V:::::H:::::::::::V:T:EP
Hmu1588         :::::::::::::::::::ST:D:Y:TQ:::N::::V:::T:H:::::::L:::S:S:EP

consensus       DEPVEVELDADHELAWFPRE-----------------------
#oth            244.5241421.3...1.2221111111123111331111111
Hut2580         :KR:R:R:AT::P:::::A::::::::::::::::::::::::
NP3648A         :D::F:SI:::::::::::GERKMADGGPDS:::TA:::::::
HVO_1707        :GC:::T:::G:::::::::QR::::::PESGLYSD:::::::
Hbo3129         :G::A::I::G:::::::::QR::::::PEA:::EQ:::::::
HQ2543A         SGV:DI:IN:::::::::::QR::::::PDE:::TDERYPRGI
hla0066         ::S:GL::T:::P:::Y::-:::::::::::::::::::::::
VNG0921         G:::A:S:VS::A:::Y:T::::::::::::::::::::::::
rrnAC0908       GQ::::D:V:::D:::Y:T::::::::::::::::::::::::
Hmu1588         G::::ID:T:::P:::Y:T::::::::::::::::::::::::