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[S] (-) COG4715 Uncharacterized conserved protein
6 genomes BUD1514 8 proteins
a Hsa
Halobacterium
sp. NRC-1		 b Hma
Haloarcula
marismortui		 f Hvo
Haloferax
volcanii		 g Hbo
Halogeometricum
borinquense		 h Hmu
Halomicrobium
mukohataei		 i Hut
Halorhabdus
utahensis		 j Hla
Halorubrum
lacusprofundi		 q Nph
Natronomonas
pharaonis		 x Hwa
Haloquadratum
walsbyi

VNG6400

 -

HVO_1735

HVO_1743

HVO_A0396

 -

Hmu2389

Hut1828

hla2124

NP3842A

 -

Pairwise sequence scores
Consensus score2099 HVO_A0396 VNG6400 hla2124 HVO_1743 Hut1828 Hmu2389 HVO_1735 NP3842A
1697HVO_A0396 2104 1768 1820 854 911 698 688 675
1702VNG6400 1768 2114 1876 789 888 708 699 644
1739hla2124 1820 1876 2107 827 904 741 719 679
1039HVO_1743 854 789 827 2028 1237 599 660 607
1083Hut1828 911 888 904 1237 2044 580 657 582
943Hmu2389 698 708 741 599 580 5024 1780 1773
939HVO_1735 688 699 719 660 657 1780 5069 3466
878NP3842A 675 644 679 607 582 1773 3466 5114 

701 symbols
consensus       ----------------MDPTRDAIRDICTDAVFERGERYREDGRIQEIDRFGTTVTATVS
#oth            1111111111111112352213411231.211.1..34.34211125132514423.212
HVO_A0396       ::::::::::::::::::V:E::V:::::::::::::::::E:::HG:H:ID:::::V::
VNG6400         :::::::::::::::::EV:E::V:::::::::::::::LA::C:H::H:VDS::I:V::
hla2124         ::::::::::::::::::V:E::V:::::::::::::::LAE:::H::H:VD:::::V::
HVO_1743        :::::::::::::::::NID:ERVKNRS::::::::VN::DE::::QL::::EL::::I:
Hut1828         :::::::::::::::::QIDEAW:::R:::::::::QH::T::::RR:::::DV:::I:Q
Hmu2389         MTRSDPDSELDPDSRDLT:::::::S:::AQS:Q::VE:V::::VRDLTVT::EAE:::R
HVO_1735        :::::::::::::::MDY:A::E::SL::EQS::::AN:YHQD::::L:ID:SEIR:::R
NP3842A         :::::::::::::::MEY:::SK::SF::EQS::::VK:Y:QD:::KLEVE:GDI::I:R

consensus       GSRQYDVRVDLATDGFAPRCDCPYDGPGDCKHVVAVLLRCVDDPPEDEGDR---------
#oth            ..43.12311254532433.2....22.3...1.....4242321445312123311111
HVO_A0396       :::::::::::::N::::W:::::::::T::::::::::::::::Q::::::::::::::
VNG6400         ::::::::::::::::T:W:::::::::A::::::::::::::::PN:::::::::::::
hla2124         :::::::::::::G::::W:::::::::A::::::::::::::::S:N::::::::::::
HVO_1743        ::KL:::T:EFGGRSIDA::T:::::G:::::::::::DIAAS::Q::SE::::::::::
Hut1828         ::S::::T:E:DESNIES::T:::::::::::::::::EIAA:::A:DSE::::::::::
Hmu2389         ::HD:RTA:::SVE::D:Q:S::::HA:E:::::::::TVIEQSA:LFDEHAEHDFGVPD
HVO_1735        ::NY:::AI:IVD::VRS::S::::YA:::::::::::AVD:RD::TMS:T::DP:::::
NP3842A         :::D::ISI:IED:TIRTV:S::::YA:::::I:::::AVE:RS::STAETADSS:::::

consensus       ------------------VEAALDGADADELRAFLRDELAEDADLRDRFLARVGEPTRKS
#oth            1111111111122222222232224232221.2.21232132532.11.11231244431
HVO_A0396       ::::::::::::::::::LDT::N::::::::::::E:::T::::::Q:::::S:S:TR:
VNG6400         ::::::::::::::::::LD:::::V:::::::::::::VA::N::::::::::::::Q:
hla2124         ::::::::::::::::::LD:::G::::::::::::::::T:T:::::::::::::M:Q:
HVO_1743        :::::::::::::::::::::VI:DVS:ED::G:A::A:::HPE::EQ::::F:DDH:-:
Hut1828         :::::::::::::::::::T:V::DVSPAD::::V:AV:::RPA::::::::Y:DAAV-:
Hmu2389         HEMLTSGVAVDDRSTRHA::R:V:E::PETM::::::V::::S:R:EQ::VA::T:AE::
HVO_1735        :::::::::::ERNETVDI:SLV:QTT:ED:::::L:IV:A:Q:I::::V:F:::D:G:T
NP3842A         :::::::::::DNSETVD:::LI:RTPD::::T::L:II:D:R:I::::V:FA::EPG:T

consensus       VDELRTEIDRLFEQANPRYGVVF--EPIDFSQWFDLAEEYRERGRHASAATVYRALAESI
#oth            1311143.222.1233434331322241..3124131341.2223553.222...24141
HVO_A0396       ::::::T:::R::ET::E:Y::::::::::TR:::::T::::Q::Y::::::::::V::L
VNG6400         ::::::A:::R::ET::E:H::::::::::T::::::N::::Q::D::::::::::V::L
hla2124         ::::::S:::R::ET::E:H::::::::::T::::::N:H::Q::A::::::::::T::L
HVO_1743        :E:Y:E::AQ::::HAD--P::::::A::::RFLEI::Q::D:E:YLA:::::::VF:E:
Hut1828         FE:::D::EA::D:YTQDHPA:T::DA:::WRF:EM::R::::D::FA::A::::IFTA:
Hmu2389         :ADY:R::::K::::TD:R:I:AYDTQL::R:YY:R:DT:::H:D:ER:L:I::::::G:
HVO_1735        :YDYKQ::::::DD:VS:R:M:EHGTH:::::YT::::TH::::HVDT:TDI:::VS:G:
NP3842A         :YDYKQ:::::::D:AG:G:MIEYDTR:::::YH::V:MH:S::NIGT:TDL::::::T:

consensus       DENMERIDGAYDHYARALSRALDGYVDCVAAAERDAEAVTDAVAFL--------------
#oth            2213311.1121.2222222.213111114343534223343343.23223322221222
HVO_A0396       :D::::V::::::FS::F::::::::::::FRG::-D:::::::::::::::::::::::
VNG6400         :D::::V::::::FS::F:::I:E::::::T:::::D:::::::::::::::::::::::
hla2124         ::::::V::::::FS::F:::::::::::::T::::D:::::::::::::::::::::::
HVO_1743        ::KYNW:::::::::K:IQT:::::A:::L:TNPTP:EFDTYAGV:::::::::::::::
Hut1828         :::EG::::::::H::::QS:::::::::I::DL:Q:RFETYAGV:::::::::::::::
Hmu2389         QQ:LD:::DSGG:::GQIE::M:VA:::INEM:S:::RRREFLDT:FEQYEATEYAFVME
HVO_1735        R::LD:V:DSSG::G:E:E::IEA:AET::EQ:FEH:RKELYIQY:CAEFVGADHGFASD
NP3842A         R:::N:::DSSG::G:E::::IE::AETITEQGYGHPEKRPHIEY:FGEFIDADYGFASE

consensus       ---------------------------------------------------------EER
#oth            212311122122311112222212212222322122122222122232312222111423
HVO_A0396       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::D::
VNG6400         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2124         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::T::
HVO_1743        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::A:
Hut1828         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::A:L
Hmu2389         YYDDALRSICETTADLEHLRSLLEPHLPSPVAE:::::::::::GDKRMDETE::::TSE
HVO_1735        DYDGALRTVCTEDADLEYWLEQLDAHVSGVTLD:AVLSGELSSKTDDRRDETED:::SAD
NP3842A         DYAEALRTICTTRADLEYWLELLDAHVSGVDLEPGALEASVGSSTETTQDDVQEDISSSE

consensus       ATSGS-----------------------------PLLAEHF-------------------
#oth            433131122222112211121112111321223213321411113112221222213332
HVO_A0396       ::::T::::::::::::::::::::::::::::::F:T::::::::::::::::::::::
VNG6400         ::::T::::::::::::::::::::::::::::::F::::::::::::::::::::::::
hla2124         :V::T::::::::::::::::::::::::::::::F::::::::::::::::::::::::
HVO_1743        ::AEP:::::::::::::::::::::::::::::RIND:Q::::::::::::::::::::
Hut1828         SSA::::::::::::::::::::::::::::::::VND:R::::::::::::::::::::
Hmu2389         GDE:G::::::::::::::::::::::LPDPTRDR:D:DLLTGGVLDIDRLSESPLDVSD
HVO_1735        TSD:::ARDDGSTDHP:::ERTDDVLYASDFTDG::STDD:TGGALDVEHLAVGTLQFEY
NP3842A         P:D::NAQSEDETDTTVENGRTDNVLYTSDFATG::STDD:TGGTLDVEHLAVGPLEIGY

consensus       ------------------------------------------------------------
#oth            111222211111222222322333233313323222223212112311122212112222
HVO_A0396       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6400         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2124         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1743        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1828         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu2389         FVGETL::::::ATKLASTEAGGATAGDSQHSQTGLSAEAQT::VVSTYAWVLSELDENE
HVO_1735        FVGDAFEELRVDEPTTVEKHTARVELTKSGTTDTDISSSLQKRRIFSTYVYILEELGDED
NP3842A         FVGDAFDELRVDAPTTVERHTVEIESPESSASESDLASKLQKRRVLSTYVYVLEELGEED

consensus       ------------------------------------------------------------
#oth            213322122221322212312221233232211322213122212232212221212122
HVO_A0396       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6400         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2124         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1743        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1828         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu2389         ALRAVLEPVATETPTLCCRYVEALLADGSDERAPAALECGLDRFGHSRELHRFAADCYRD
HVO_1735        ALSQLYEEIYLESKRFCKEYARRLIDEGNENRAIEVVEDGIHTFRSARELRWLAADLYED
NP3842A         VLDTLYEEIYLEDKRFCKAYAERLIEQDDEERALEVVEHGIDTFRSTTDLRWLAVDLYRN

consensus       ------------------------------------------------------------
#oth            123231222122212223213111212321313113122222223232312321232122
HVO_A0396       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG6400         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2124         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1743        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1828         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu2389         RDDERYRDLLQTMFVRFADWEAYDELVSACPDDEWESVFHGLVSQLGRLDADRLIDLYIR
HVO_1735        RDMDEYRATLKQLFLDHTEWAAYDDLKTICDDQEWQSIYGEFERHFERDDRKDLVALYVH
NP3842A         REPDKYKALLKQLFLDHSEWDAYDELKEACTDREWASIYGEFERTLDQRDRQRLISMYVH

consensus       ----EKALVELQEKADEQSCR---------------------------------------
#oth            232211.35214145433353212222123213211131113132221221112111322
HVO_A0396       :::::::V:::::::::::FE:::::::::::::::::::::::::::::::::::::::
VNG6400         :::::::A:::R::LG::::E:::::::::::::::::::::::::::::::::::::::
hla2124         :::::::A::::::I:::::K:::::::::::::::::::::::::::::::::::::::
HVO_1743        ::::RR::DD:E:RYE-----:::::::::::::::::::::::::::::::::::::::
Hut1828         ::::RR::E::E:RR------:::::::::::::::::::::::::::::::::::::::
Hmu2389         EGER::::SRVLDGE:PELL:QYQTDLADLDPEAYFETYREVLASHLADDTGRDHYRAVI
HVO_1735        DDDL:R:FA::K:N::LS:V:QYRDPVATTAPVEYFELYRELLVPFAAGDTGRRHYRDIA
NP3842A         EMDL:::FF::K:AENLSWM:RYQDPVATVDPIEYFEMYREQLIPFAAGETGRRHYREIA

consensus       -----------------------------------------
#oth            21122122123222122113212221111112111122121
HVO_A0396       :::::::::::::::::::::::::::::::::::::::::
VNG6400         :::::::::::::::::::::::::::::::::::::::::
hla2124         :::::::::::::::::::::::::::::::::::::::::
HVO_1743        :::::::::::::::::::::::::::::::::::::::::
Hut1828         :::::::::::::::::::::::::::::::::::::::::
Hmu2389         GHLREMSQLAFDEELAAFVARLRESHSNRPALLDELDDARF
HVO_1735        DHLEEMQGLVPEARLEEFVDFLKDKHSNRPAFLDELEKAGF
NP3842A         DHLESMQGLVSDARLEEFVEFLKDKHSNRPAFLDELEKAGF