Halo-Ed: Extreme Microbiology and Astrobiology Education and Outreach

DasSarma Lab

Halo-Ed Portal

Halo-Gen

HaloWeb

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Introduction

 

Introduction

 

Extremophilic microorganisms offer an ideal way to teach and learn about astrobiology, life in extreme environments on Earth, and fundamental concepts of microbiology and molecular genetics. We have developed Halobacterium sp. NRC-1, a salt-loving member of the Domain Archaea, which we use as a model organism for research in our laboratory, for extreme microbiology, and astrobiology education. Both inquiry-based educational kits for the classroom, The Model Microbe, and a companion genomic database, HaloWeb, serve as resources for students and teachers. In addition, MolGenT, an electronic tutor illustrating concepts of life on Earth, is available to the community. Upon completion of the MolGenT Test, participants can obtain a certificate. Activities for younger students are also available. These resources are ideal for understanding principles of extreme microbiology, the new field of astrobiology, and are suitable for students of all ages.

 

journalcovers

 

Covers highlighting Haloarchaeal research from our laboratory

 

Our hands-on laboratory modules available through Carolina Biological Supply Co. are called Microbiology I, Life in Extreme Environments, and Antibiotics in Action. Please note, to order pre-poured plates for growing the microbes, you will need to call Carolina and request the following (currently unlisted) item number: 821536. We are working on getting this listed in the near future!

 

In addition to the programmed exercises, students can explore research questions, many of which are currently engaging scientists in various fields, from microbiology to astrobiology. Students are encouraged to ask outstanding questions like 'How did life originate on Earth?', 'What conditions limit life on Earth?' and 'Is there life elsewhere in the universe?'. The exercises have been recognized and certified by the AP Board, see The American Biology Teacher.

 

All of our exercises are based on the extremely halophilic microbe Halobacterium NRC-1, which has the remarkable ability to survive under multiple extreme conditions. Moreover, the nearly saturating concentration of salts makes its growth medium safer by inhibiting most harmful contaminants. The microbe is also colorful, easy to culture, grows well at standard temperatures, and is widely distributed in nature. It is also genetically tractable and the genome has been completely sequenced. NRC-1 has several applications in biotechnology and medicine.

 

Students and teachers may also be interested in talks and webinars from the DasSarma Lab:

Ancient Pink and Purple Microbes for Research and Education (18 minutes)

Evolution and Survival of Ancient Microbes: Deep Underground, Above the Atmosphere, and Possibly on Mars (47 minutes)

Earth's Extremophiles and the Search for Life on Mars (36 minutes)

Diversity of Archaeal Photo Pigments and Implications for Biosignatures (13 minutes)

Extreme Biotech: Understanding Extremophile Biology to Impact Human Health (27 minutes)

Professor Shiladitya DasSarma's tribute lecture for Prof Khorana on his birth centenary in January 2022 (53 minutes)

Haloarchaea - Novel Microbes for Integrating Bioinformatics with Laboratory Experiments: From Astrobiology to Zoonotics (47 minutes)

Haloarchaea: Potential for space travel (22 minutes)

 

Fig22.1. World map with isolation countries of Haloarchaea with full genome and proteome public sequences.jpg

Map of the World, showing the countries from which the 100+ Haloarchaea with publically available complete genomes and proteomes are available (Purple color). @ Priya DasSarma, Created and reproduced with permission, using mapchart.net.

 

For Questions and Suggestions, contact the Halo-Ed Team

MolGenT

Microbiology

DNA Extraction

Mutations

Life in Extremes

Antibiotics

Bioinformatics

Teachers

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Copyright © Shiladitya DasSarma & Priya DasSarma